Beth Shapiro, Chief Scientific Officer at Colossal Biosciences and author of How to Clone a Mammoth, dives into the thrilling world of de-extinction. She discusses the quest to resurrect iconic species like the woolly mammoth and dodo through genetic engineering and ancient DNA analysis. The ethical implications and scientific hurdles of this ambitious endeavor are explored, along with the innovative technologies fueling the revival. Plus, Beth shares humorous tales about collecting ancient DNA, showcasing the adventurous side of cutting-edge science.
Beth Shapiro discusses the complexity of de-extinction, emphasizing that recreating species involves integrating engineered traits into modern ecosystems rather than achieving exact replicas.
Innovative genetic technologies, such as stem cell manipulation and genome editing, hold significant potential for conservation efforts and the revival of extinct species like the woolly mammoth and dodo.
Deep dives
Exploring Shoe Trends for Fall
The podcast highlights the exciting shoe trends for the fall season, emphasizing styles that cater to various preferences. Bold snake print boots and retro sneakers with animal print details make a statement for those feeling fierce. On a softer note, kitten heels are presented as fashionable yet comfortable options, appealing to those seeking a more demure look. The variety offered, including edgy moto boots and simple ballet flats, ensures that there is a perfect choice for every wardrobe.
The Concept of De-Extinction
A notable focus of the discussion is the concept of de-extinction, particularly the efforts to bring back extinct species like the woolly mammoth and the dodo bird. Beth Shapiro, a leading expert in the field, explains the technical and biological hurdles involved in this complex scientific endeavor. She clarifies that achieving an exact replica of these species is impossible; instead, the goal lies in recreating traits that allow them to fit into modern ecosystems. This perspective shifts the conversation from mere revival to integrating engineered species into current ecological frameworks.
Innovative Genetic Techniques
The podcast delves into the innovative genetic techniques being developed to aid in de-extinction and conservation efforts. One significant advancement is the manipulation of induced pluripotent stem cells derived from living elephants, which could eventually replicate traits of the woolly mammoth. Additionally, discussions include methods for editing bird genomes to revive species like the dodo through intricate processes that involve preserving primordial germ cells. These technologies hold promise not only for de-extinction but also for broader applications in conservation biology.
Collaborative Conservation Efforts
The importance of collaboration between scientific endeavors and conservation initiatives is emphasized throughout the episode. Shapiro mentions partnerships with organizations like the Mauritian Wildlife Foundation, which are crucial for maintaining ecosystems where extinct species once thrived. Such collaborations are aimed at restoring habitats and ensuring that newly engineered species can thrive in environments similar to their historical surroundings. The excitement around these projects fosters community engagement and support for ongoing conservation efforts.
*Or at least, sort of bringing back mammoths and dodos.
Beth Shapiro is the chief scientific officer at Colossal Biosciences and the author of How to Clone a Mammoth: The Science of De-Extinction. Beth's problem is this: How do you use the tools of modern biology – and hundreds of millions of dollars – to bring back species that have been extinct for centuries? And on another level, Beth’s problem is explaining to the world what it really means (and doesn’t mean) to bring back an extinct species.