Drs. Karl and Spencer discuss how semaglutide impacts the heart with new trial data available. Learn how semaglutide may reduce risks of heart attacks and also how it impacts your quality of life if you have heart failure.

Dr. Andrea Love, a microbiome expert, joins the hosts to discuss the importance of the microbiome and debunk myths surrounding it. They delve into its impact on digestion, immunity, body weight, and metabolism. The episode also explores the factors that influence the microbiome, questions marketing claims, and emphasizes the need for reliable tests and research.

Drs. Karl and Spencer chat with Amy Goekel about her history of her eating disorder. Amy has her own podcast where she discusses it is more depth as well https://podcasts.apple.com/us/podcast/the-eating-disorder-diaries/id1666122772

Dr. Andrea Love, a cancer immunologist, joins the hosts to discuss the controversy surrounding the recent headlines about aspartame being listed as a possible carcinogen by the WHO. They explore the classifications of the International Agency for Research on Cancer, the safety of aspartame consumption, and the controversy surrounding diet soda.

Expert in internalized bias, Dr. Rebecca Pearl discusses addressing weight bias and stigma, methods and results of weight loss studies, practical strategies for clinicians, and understanding biases in medicine.

Drs. Karl and Spencer chat with Dr. Jesse Richards all about BBS (Bardet Biedl Syndrome), an unknown cause of genetic obesity.

Dr. Nagra, an expert in artificial sweeteners, joins Drs. Karl and Spencer to discuss the recent WHO news about artificial sweeteners. They clarify the confusion around WHO's recommendations, emphasize the need for further discussion, and highlight the importance of replacing sugary drinks with artificial sweeteners for weight loss.

Drs. Karl and Spencer discuss with cardiologist Dr. Luke Laffin about his recent study looking at statins versus various supplements touted as cholesterol-lowering. We also discuss the claim about saunas being better than drugs at lowering mortality.

Drs. Karl and Spencer chat with Dr. Angela Fitch, the president of the Obesity Medicine Association and a fellow doc who lifts! They discuss Dr. Fitch's journey into lifting along with the importance of body composition in obesity management. Dr. Fitch is also the CMO of her new company KnownWell. Need an online workout program? Check out LiftRx

Drs. Karl and Spencer bring back Dr. Grant Tinsley, a body composition researcher, to go over the GLP-1 data (semaglutide and tirzepatide) in terms of lean body mass loss. Learn:- How much lean body mass is lost in these trials- How body composition is measured- How is muscle loss assessed- Should you be worried if you're taking a GLP-1 agonist Read Dr. Tinsley's blog