This Week in Virology

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Ashlee Bennett The TWiV crew discusses two reports on viruses that might have crossed kingdoms, from plants to honeybees and from plants to vertebrates. Links for this episode Tobacco ringspot virus in honeybees (mBio) Plant virus that switched to vertebrates (PNAS) CDC influenza activity and surveillance With Esmeralda at ASM Biodefense (jpg) Image credit: Virginia Tech Learning Resources Center Letters read on TWiV 271 Weekly Science Picks Alan - Nagasaki bombing (YouTube)Rich - GoPro Red Bull Stratos (YouTube)Dickson - Solar orbsVincent - Socrative Listener Pick of the Week Basel - Pathology course onlineRussell - Sochi 2014: Encyclopedia of spendingYegor - Visual Science Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Rich Condit Guests: Dennis Hruby and Yoshihiro Kawaoka Vincent and Rich discuss avian influenza virus and an antiviral drug against smallpox with Dennis and Yoshi at the ASM Biodefense and Emerging Diseases Research Meeting in Washington, DC. Links for this episode ASM Biodefense Meeting Influenza H5N1 transmission (Virus Res) Aerosol transmission of H5N1 virus in ferrets (Nature) Characterization of H7N9 virus from humans (Nature) ST-246 efficacy in primates (AAC) Antiviral options for biodefense (Curr Op Virol) ST-246 safety in humans (Antimicrob Agents Chemother) Gain-of-function experiments (Science) Letters read on TWiV 270 Video of this episode - view at Vimeo Weekly Science Picks Vincent - Quanta MagazineRich - Colour is in the eye of the beholder Listener Pick of the Week Kehau - Beautiful but deadly viruses Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16. Links for this episode IFI16 is a nuclear pathogen sensor (Cell Host Micr) Nuclear IFI16 sensing of and antagonism by herpesvirus (PNAS) Acetylation regulates IFI16 location (PNAS) Letters read on TWiV 269 Weekly Science Picks Kathy - Female conveners and speakersAlan - SandgrainsRich - 2013 Lamborghini AventadorVincent - Happy Birthday Mac and 128K Mac teardownDickson - Farmdominion Listener Pick of the Week Peter - The Microscope and The Next Global KillerRichard - Glass viruses Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Ashlee Bennett Vincent, Alan, Kathy, and Ashlee discuss fomites in physicians offices, plant virus factories involved in aphid transmission, and clues from the bat genome about flight and immunity. Links for this episode How viruses cause disease (Coursera) How clean is your iPad (Which?) Meeting announcement: From emerging to pandemic viruses CaMV virus factories involved in aphid transmission (J Virol) Caulimovirus (ViralZone) CaMV responds instantly to vector (eLIFE) Aphid acquiring CaMV (J Virol) Bat genomes, flight, and immunity (Science) Letters read on TWiV 268 Weekly Science Picks Kathy - Jean-Luc Doumont (slides, communicating science, website, Scitable)Alan - Wireless thermometerVincent - LORiOLA viral necklaces Listener Pick of the Week Jessica - Knit icosahedronRobert - Practical computing for biologists by Haddock and DunnStephen - Fourteen years of US weather (YouTube) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich and Kathy review a protease essential for influenza pathogenesis in mice, and directionality of rhinovirus RNA exit from the capsid. Links for this episode Protease essential for influenza pathogenesis in mice (PLoS Path) Rhinovirus uncoating is directional (PLoS Path) Fluorescence correlation spectroscopy Capillary electrophoresis (Wiki) Letters read on TWiV 267 Weekly Science Picks Kathy - Amazing mapsAlan - Florida to NJ in 156 seconds (YouTube)Rich - Whiteout over Great Lakes from SpaceVincent - LORiOLA viral necklaces Listener Pick of the Week Carol - Knit picornavirusRobert - RNA: Life's Indispensible Molecule by James Darnell,and Biochemical Pathways by Michal and Schomburg Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy discuss finding viruses in outer space, varying results obtained from personal genetic testing, and depletion of CD4 cells during HIV infection by pyroptosis. Links for this episode We should hunt for viruses in space (New Scientist) I had my DNA picture taken (NY Times) CD4 cell death by pyroptosis (Nature) Abortive HIV infection in lymphoid tissue (Cell) IFI16 sensor required for HIV mediated cell death (Science) PubMed Commons Preferential CTL targeting of Gag (Cell Rep) Exonic transcription protein binding (Science) Letters read on TWiV 266 Video of this episode - view at YouTube Weekly Science Picks Kathy - 17 mundane things, mind blowing viewsAlan - SnowovelVincent - Public's views on human evolution Listener Pick of the Week Emily - Dengue pillow Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler In their final episode of the year, the TWiV team reviews ten compelling virology stories from 2013. Links for this episode Antiviral RNAi (TWiV 255, 256, 263) MERS-CoV (TWiV 215, 223, 224, 233, 239, 247, 251, 258) Placental trophoblasts confer viral resistance (TWiV 241) Origin of REV (TWiV 248) Phage T7 gets a cat scan (TWiV 220) It's a cGAS! (TWiV 222) Dual virus-host arms race (TWiV 242) Pandoraviruses (TWiV 246, 261) CMV based SIV vaccine (TWiV 254) Threading the NEIDL Letters read on TWiV 265 Video of this episode - view at YouTube Weekly Science Picks Kathy - Women in ScienceAlan - ContagiumRich - RC helicopter (demo)Vincent - The athletic power of quadcopters Listener Pick of the Week Lindsay - Alcohol consumption and vaccines (Vaccine)Johnye - The Singing Microbiologist Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiVites read listener questions and comments about public engagement in science, vaccines, RNAi, reprogramming CD8 cells to treat cancer, rabies, and much more. Links for this episode Viral gifts Controlling plant viruses by vector control (Ann Rev Phyto) Flavivirus RNAi suppressor (J Virol) Entre probetas podcast (iTunes) Hedgehog central Reprogramming T cells for leukemia therapy (NEJM) Petri Dish podcast On Your Mind podcast Letters read on TWiV 264 Weekly Science Picks Kathy - Sorting algorithms visualizedAlan - StratodeanRich - Art in Science by Polyxeni PotterVincent - Pixel Genes Listener Pick of the Week Judi - Olympus BioScapes Winner Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Ben tenOever Ben joins the TWiV team to reveal the winner of his contest in which influenza viruses carrying different interferon-stimulated genes vie against one another in mice. Links for this episode Virusninja Game of clones (Vax Rep) Game of clones bracket Letters read on TWiV 263 Weekly Science Picks Kathy - The Brain Scoop, esp. Where My Ladies AtAlan - Say 'hi' to a spaceship (YouTube)Rich - Garmin BlueChart Mobile and Active CaptainVincent - Journal boycott (one, two)Dickson - Futurescape TV show Listener Pick of the Week Luis - Spillover by David QuammenKen - Gravity Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guest: Ann Palmenberg Vincent returns to the University of Wisconsin - Madison to speak with Ann Palmenberg about her career in virology. Links for this episode Palmenberg lab website - great resources Genome sequences of all rhinoviruses (J All Clin Imm) Cardioviral poly(C) tracts (Arch Virol Supp) EMCV disruption of nuclear transport (PNAS) Picornavirus protease in replicase gene (J Virol) Bacteriophage Qbeta replicase (J Virol) Thanks to Jordan for the episode title! Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv