TWiV 269: Herpesvirus stops a nuclear attack

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16.

Links for this episode

• IFI16 is a nuclear pathogen sensor (Cell Host Micr)
• Nuclear IFI16 sensing of and antagonism by herpesvirus (PNAS)
• Acetylation regulates IFI16 location (PNAS)
• Letters read on TWiV 269

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