Biohacking Beauty: The Anti-Aging Skincare Podcast

Most people think menopause is just about hot flashes and mood swings—but what if I told you it’s actually one of the biggest drivers of skin aging? From collagen loss to increased sensitivity, breakouts, and inflammation, hormonal shifts can make you look older, faster. And yet, no one is talking about it.To uncover the real impact of menopause on skin health (and what you can do about it), I’m joined by Dr. Jessica Shepherd, an OB-GYN, menopause expert, and founder of Sanctum Med & Wellness. She’s on a mission to rewrite the menopause narrative, showing women how to take control of their skin, hormones, and longevity.In this episode, we dive into the real impact of estrogen decline on skin aging, why some women experience sudden breakouts or rosacea in midlife, and how hormone replacement therapy (HRT) can play a role in both skin health and longevity. We also explore the connection between gut health, inflammation, and skin vitality, as well as the cutting-edge treatments and biohacking strategies that are changing the game for menopausal women.Dr. Shepherd is also the author of Generation M, a book that serves as both a medical and lifestyle guide for women navigating this stage of life. She breaks down why menopause isn’t just a phase, it’s a long-term shift that requires a strategic approach to aging well.If you’re looking for science-backed strategies to optimize your skin, hormones, and overall well-being through perimenopause and menopause, this episode is a must-listen.We Also Discuss:(00:02) Women's Health and Skin Aging(09:31) Hormone Therapy and Skin Rejuvenation(17:29) Effective Skincare Ingredients and Approaches(21:46) Longevity and Gut Health for Skin(31:42) Importance of Sleep for Longevity(39:08) Future of Women's Health Therapies(52:16) Embracing Aging With Agency and CuriosityLearn more about:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/   Instagram: @young_goose_skincareDr. Jessica Shepherd➡️ Exclusive for Biohacking Beauty ListenersIf you’re serious about optimizing your skin health and hormones, here’s something special for you: Anyone who visits Dr. Jessica Shepherd’s clinic, and mentions the Biohacking Beauty Podcast will receive a complimentary skin consultation.Instagram: @jessicashepherdmd​Twitter: @JShepherd_MD​LinkedIn: Jessica Shepherd, MD, MBA, FACOG​Book: Get Dr. Jessica Shepherd’s Book Generation M

Discover the transformative effects of red light therapy on skin health, including its role in boosting collagen and reducing inflammation. Learn why using red light alone isn't enough and how the right biochemical environment enhances results. The hosts delve into the powerful LADR serum, packed with DNA repair enzymes and antioxidants that work synergistically with red light to optimize skin regeneration. Get insights on creating an effective skincare routine and maximizing the benefits of these innovative treatments.

Anastasia Khodzhaeva, co-founder of Young Goose and a skincare entrepreneur, shares her journey with Botox and TMJ treatments. She reveals why Botox didn't work for her and discusses effective natural alternatives like peptides and NAD precursors for youthful skin. The conversation dives into the science of Botox, its risks, and the myth of its preventative benefits. Anastasia also highlights the importance of autophagy for skin rejuvenation and shares her techniques, including facial tapping and massage, for achieving a youthful glow without neurotoxins.

Discover the fascinating role of telomeres, the protective caps on chromosomes that shorten with age. Learn how oxidative stress and inflammation accelerate this process while uncovering ways to slow or potentially reverse telomere shortening. Dive into cutting-edge research on NAD metabolism and autophagy, as well as practical lifestyle changes and supplements that promote cellular longevity. Explore how skincare strategies can also impact telomere health, making it an essential conversation for anyone invested in their anti-aging journey.

In this enlightening discussion, Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Fatty15, reveals groundbreaking insights about C15, the essential fatty acid identified through studies of long-lived Navy dolphins. She explores how C15 strengthens cell membranes, combats oxidative stress, and influences epigenetic aging. Dr. Venn-Watson also explains why modern diets lack this vital nutrient and its role in enhancing skin health and metabolic function, advocating for its supplementation as a powerful addition to our diets.

Discover the future of skincare that goes beyond quick fixes! Learn how NAD+ acts as the 'molecule of life,' boosting skin repair at the cellular level. Dive into the benefits of spermidine, which activates autophagy to renew skin by eliminating aging cells. Uncover the game-changing role of copper peptides in collagen remodeling and why advanced vitamin C derivatives outperform traditional forms. Finally, explore how targeting senescent 'zombie cells' can dramatically slow aging and reduce inflammation. It's time to revolutionize your skincare routine!

Today, we’re diving into something that goes way beyond skincare, how your skin is actually a powerful window into your overall health and longevity. Most people think of aging as just wrinkles and fine lines, but the reality is that what’s happening on the surface is a direct reflection of what’s going on at the cellular level.To explore this, I’m joined by Nick Engerer, a longevity scientist and the founder of A Longer Life, where he helps people take a data-driven, strategic approach to optimizing health and aging. Nick’s work is all about cutting through the noise, moving beyond trends and hype to focus on what actually works when it comes to extending healthspan and improving quality of life.In this episode, we get into why your skin and hair are some of the most revealing biomarkers of aging, how UV exposure accelerates biological aging in ways most people don’t realize, and what you can do to slow that process down. We also tackle one of the biggest challenges in wellness today, decision fatigue. With endless options for supplements, treatments, and interventions, how do you know what’s actually worth your time and money?Nick’s background is unique, he started as a solar radiation scientist before pivoting into longevity science, bringing a data-driven approach to proactive health. Through A Longer Life, he’s building a framework to help people apply longevity strategies in a practical, sustainable way.If you want to learn how to take control of your skin health, optimize your longevity, and navigate the overwhelming world of wellness with confidence, this episode is for you.We Also Discuss:(00:00) The Essence of Biohacking(14:36) Investing in Longevity and Skincare(22:16) The Science of Skincare and Aging(31:45) Reproductive Signals and Longevity Strategy(45:03) Navigating Wellness and Longevity Overwhelm(54:21) Optimizing Evening Routine for Wellness(01:00:12) Exploring New Mindset CourseLearn more about:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincareNick Engerer

Discover how true skin rejuvenation begins at the cellular level, not just the surface. Learn about mitochondrial dysfunction and the role of NAD decline in aging. Traditional anti-aging products often miss the mark; innovative biohacking ingredients like NAD+ and copper peptides are changing the landscape. Explore the science behind skin aging and the potential to actually reverse it. This podcast dives deep into reprogramming skin cells for longevity, moving beyond quick fixes to real solutions for ageless skin!

Welcome back to Biohacking Beauty! Today, we’re diving into the cutting-edge science of biological vs. chronological aging and how epigenetic testing is revolutionizing the way we understand skin longevity. Aging isn’t just about the number of birthdays you’ve had—it’s about how your cells are aging at the molecular level. And now, thanks to advancements in epigenetics and AI-driven diagnostics, we can measure and even influence that process.In this episode, I sit down with Hannah Went, an expert in biological age testing and the Director of Operations at TruDiagnostic, a leading epigenetics company. We explore how biological aging manifests in the skin, why epigenetic markers are more predictive of health than genetics, and how personalized interventions can actually slow or even reverse aging at the cellular level.Hannah also shares groundbreaking research on how lifestyle choices, like diet, sleep, and even skincare, can alter gene expression and influence the rate at which we age. Plus, we discuss how advanced testing methods can provide real-time feedback on how well anti-aging interventions are actually working. If you’ve ever wanted to take a data-driven approach to longevity, this episode is packed with insights you won’t want to miss.Hannah Went is the Director of Operations at TruDiagnostic, a company at the forefront of biological age testing and longevity research. With a background in epigenetics and functional medicine, she’s dedicated to helping individuals track and optimize their health using cutting-edge diagnostic tools.We Also Discuss:(00:01) Epigenetics and Biological Age Testing(13:47) Aging and Skin Link Exploration(26:13) Genetic Influence on Phenotype and Aging(31:37) Aging, Skin Health, and Lifestyle Factors(44:43) At-Home Genetic Testing SupportLearn more about:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincareHannah WentWebsite: everythingepigenetics.com Instagram: @everythingepigenetics

Have you ever wondered why traditional sunscreens aren’t enough to protect your skin from all forms of light damage? In this episode of Biohacking Beauty, I’m sitting down with Jamie McGuire to break down the truth about blue light exposure, SPF, and effective melasma protocols.We dive into why hyperpigmentation often worsens with artificial light exposure, the importance of full-spectrum protection, and how Young Goose’s innovative formulas address common skin concerns like melasma, sensitivity, and inflammation. Plus, we tackle the "clean beauty" debate—are some ingredients being unfairly criticized?Jamie McGuire is a skincare expert with over 15 years of experience in personalized skincare protocols. Her holistic approach focuses on helping clients achieve long-term skin health through science-backed recommendations and innovative biohacking products.Whether you’re dealing with melasma or looking for smarter protection against blue light, this episode offers valuable insights and real solutions to refine your routine for radiant, resilient skin.We Also Discuss:46:04 - 49:10 – The Reality of "Clean Beauty": Understanding Controversial Ingredients49:11 - 50:39 – Melasma and Hyperpigmentation: Understanding the Triggers50:40 - 54:30 – Melasma Protocol Breakdown: Step-by-Step Routine54:31 - 57:07 – The Power of BioShield SPF 40: Protection Beyond UV Rays57:08 - 01:00:13 – Why Retinol Sensitivity Happens (and How Bioretinol Prevents It)01:00:14 - 01:02:23 – Red Light Therapy Synergy with Green Tea Phyto SerumLearn More AboutJamie McGuireInstagram: @jamieanneaestheticsWebsite: www.jamieanne.co/Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincare