The Peter Attia Drive

Kelsey Chittick, author of "Second Half: Surviving Loss and Finding Magic in the Missing," shares her impactful journey of healing after the sudden death of her husband, former NFL player Nate Hobgood-Chittick. She discusses the challenges of parenting through grief, her experiences with psychedelics, and the concept of radical acceptance. Kelsey reflects on navigating trauma, the complexities of mental health, and how she’s rediscovered happiness in life’s unpredictability, offering profound insights into healing and resilience.

Join Dr. Matt Kaeberlein, a leading researcher in aging from the University of Washington, as he dives into the fascinating world of anti-aging compounds. They explore the roles of NAD+, metformin, and rapamycin, discussing their potential in extending lifespan. Tune in for insights into aging biomarkers and the challenges in understanding epigenetic clocks. Kaeberlein shares skepticism surrounding commercial aging tests and emphasizes the need for thorough research models to make informed decisions in longevity science.

Explore the keys to longevity through exercise! Discover how strength training and techniques like deadlifts play a crucial role in maintaining muscle mass as we age. Learn about the benefits of zone 2 and zone 5 training for optimizing aerobic capacity and cardiovascular health. Delve into the concept of the 'Centenarian Olympics' and the importance of functional fitness tailored for a vibrant life into your 100s. Plus, gain insights into balancing exercise routines and why stability should be at the core of all movement.

Layne Norton, Ph.D., a leading expert in nutritional sciences and a renowned physique coach, dives deep into the science of energy balance and its impact on body composition. He explains how tracking calories can be tricky and offers tailored nutrition advice for individuals at different life stages. The conversation highlights the crucial role of protein and resistance training in muscle gain and metabolic health. Layne also discusses effective supplement options like whey protein and creatine, demystifying their benefits for fitness enthusiasts.

Nir Barzilai, M.D., the Director of the Institute for Aging Research at Albert Einstein College of Medicine, shares groundbreaking insights about longevity. He reveals genetic clues from centenarians, discussing how specific gene variants contribute to long lifespans. The conversation explores the TAME trial, emphasizing the potential of metformin as a longevity tool and its varied impacts on health. Barzilai also touches on epigenetic clocks and the controversial role of NAD precursors in aging, inviting listeners to reconsider their understanding of what it means to live a longer, healthier life.

Dive into the silent threat of atherosclerosis, the leading cause of heart disease. Discover how this condition can start early in life and the critical role cholesterol plays in our health. Learn about essential risk factors and the importance of preventive measures to combat this pervasive issue. Explore the significance of diagnostic tests like coronary artery calcium scores and their impact on understanding heart health. Finally, grasp key takeaways for effective prevention strategies against cardiovascular disease.

Join Nick Stenson as he chats with Peter Attia about his evolving views on health and wellness. They delve into advancements in cancer immunotherapy and the importance of aggressive screening for colorectal cancer. Peter discusses the significance of ApoB levels in cardiovascular risk and the role of genetics in Alzheimer’s disease. They also explore the benefits of time-restricted feeding, the complexity of nutrition, and the intriguing connection between psychedelics and mental health. Plus, don't miss a lively discussion on Formula 1 racing strategies!

In a heartfelt remembrance of Sarah Hallberg, a pioneering Medical Director at Virta Health, this conversation dives deep into her groundbreaking work on carbohydrate restriction for treating type 2 diabetes. Sarah challenges conventional dietary beliefs, illuminating the significant role of fatty acids and personalized health strategies. She openly shares her own battle with lung cancer, intertwining her professional insights with poignant personal reflections on resilience, family, and advocating for health equity, all while redefining diabetes management.

Iñigo San-Millán, an internationally renowned applied physiologist, dives into the intricacies of exercise metabolism and health. He shares insights from working with Tour de France champion Tadej Pogačar on lactate levels and fat oxidation. Discover how Zone 2 training enhances mitochondrial function and its implications for longevity. Iñigo explains methods for measuring Zone 2 thresholds, the benefits of incorporating high-intensity training, and discusses mitochondrial health in relation to long COVID and metabolic performance.

This discussion dives deep into hydration, covering water distribution in the body and the vital role of tonicity. Discover the differences between dehydration and volume depletion, and learn how they can impact your health. Explore hydration strategies and when to incorporate electrolytes or glucose. The speaker shares insights on various sports drinks, highlighting the standout options. Personal experiences lead to a renewed focus on hydration's importance for performance and overall well-being.