JAMA Network

In this engaging discussion, G. Caleb Alexander, MD, MS, from Johns Hopkins Bloomberg School of Public Health, and Hemalkumar B. Mehta, MS, PhD, dive into the burgeoning use of glucagon-like peptide-1 (GLP-1) agonists among bariatric surgery patients. They reveal that 14% of these patients initiate GLP-1 therapy due to insufficient weight loss, highlighting prescription trends and the evolving guidelines in this field. The conversation also emphasizes the vital need for better communication between patients and physicians about weight management post-surgery.

Interview with Margaret Infeld, MD, MS, author of Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction: Follow-Up of the myPACE Trial. Hosted by Robert Bonow, MD. Related Content: Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction

In this enlightening discussion, Alison J. Huang, a prominent professor at UCSF, and Stephanie Faubion, a leading expert at the Mayo Clinic, tackle the complexities of managing menopausal vasomotor symptoms like hot flashes and night sweats. They delve into FDA-approved non-hormonal medications and evaluate their effectiveness compared to traditional options. The conversation highlights the significant challenges women face, including insurance hurdles and the need for better healthcare provider training. Misinformation and the importance of evidence-based treatments are also key topics, emphasizing the need for informed patient-provider conversations.

Anna D. Ratzliff and Andrew J. Saxon, both experts from the University of Washington School of Medicine, discuss innovative collaborative care models for treating opioid use disorder. They address the alarming rise in opioid-related fatalities and the need for better healthcare access. The duo highlights their study, showcasing how structured collaborative care improves treatment outcomes and mental health quality of life. They also delve into the creation of a specialized registry aimed at optimizing care integration within existing primary care systems.

Three editorial fellows share their transformative experiences at a leading internal medicine journal. They delve into the challenges and rewards of the fellowship, highlighting personal growth and teamwork. The impact on their writing and understanding of scientific literature is profound, showcasing the importance of clear communication in medical contexts. They also reflect on honing research skills and the value of strong editorial processes. Friendships formed during the fellowship contribute to a richer understanding of the medical field.

Colin P. Derdeyn, a leading interventional neuroradiologist from the University of Virginia, joins the conversation to discuss groundbreaking treatments for acute ischemic stroke. He delves into the challenges of conducting trials for drugs like intravenous Argatroban and Eptifibatide, exploring their efficacy in improving neurologic outcomes. The talk also highlights the potential of adjunct therapies to enhance thrombectomy procedures and the ongoing quest for better patient recovery methods following strokes.

Nyssa Fox Farrell, an otolaryngologist specializing in COVID-related olfactory dysfunction, joins pain management specialist Lara W. Crock to discuss their research on using stellate ganglion blocks for treating COVID-19 induced parosmia. They share compelling patient stories and explore the innovative application of this technique for olfactory dysfunction. The conversation delves into the historical context of stellate ganglion blocks, challenges in study methodologies, and the importance of ethical practices in developing effective treatments.

An insightful interview delves into the use of prophylactic antibiotics for cirrhosis patients experiencing upper gastrointestinal bleeding. Recent findings challenge traditional guidelines, revealing no clear mortality benefits and raising concerns about antibiotic resistance. The conversation also highlights advancements in cirrhosis care and the importance of tailored treatment strategies. Experts discuss the complexities of antibiotic effectiveness and the need for further research to refine clinical practices in this area.

In this engaging discussion, Ehsan Rahimy, a leading expert in vitreoretinal diseases, sheds light on the promising role of mTOR inhibitors in preventing proliferative vitreoretinopathy (PVR). He dives into the significance of mTOR as a cellular regulator and its implications for retinal health. Rahimy reviews remarkable data showcasing a 40% reduction in retinal detachment risks through mTOR therapies. Plus, he emphasizes the need for randomized clinical trials to validate excitement in innovative treatments, setting a hopeful tone for future retinal surgeries.

Adam J. Luginbuhl is a surgical oncologist at the Sidney Kimmel Comprehensive Cancer Center, specializing in immunotherapy for head and neck cancer. Jennifer M. Johnson, also from the same center, focuses on treating advanced cases with immunotherapy. They delve into the impact of neoadjuvant nivolumab on HPV-negative head and neck squamous cell carcinoma, discussing patient outcomes and the critical role of early treatment responses. The conversation highlights the evolving dynamics in tumor boards and the importance of personalized care in enhancing patient survival.