Will Manidis is the CEO and founder of ScienceIO, which builds data solutions for health care. He was previously a managing partner at Dorm Room Fund, and a Thiel Fellow.Auren and Will discuss American dynamism and the future of knowledge work. Will breaks down his view that technology has not improved our lives as much as it should have. He explains how the nature of platform shifts have accelerated tech earnings over the last decade, but kept actual progress low. Will and Auren also do a deep dive on healthcare: why it’s so expensive, why healthcare data is so difficult to work with, and what can be changed. Will emphasizes the need for more usable healthcare data and breaks down how operational workflows consume most of the healthcare dollars spent in the US. They also discuss Will’s practical advice for young founders (as a founder and former Thiel fellow), his early work on classical Greek and Latin, and why everyone should believe in demons.  World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and Will Manidis on Twitter at @WillManidis.

Avlok Kohli is the CEO of AngelList and the founder of FastBite and Fairy. Auren and Avlok discuss the underestimated impact of AI and how it could be creating a tech mega cycle. Avlok explains the importance of unique data as a moat for companies building on top of large language models, and how this technology can disrupt incumbents. They also discuss the rise of Dual Threat CEOs and their outsized success in early stage venture capital. Avlok makes the case for why more current operators should start funds, and explains why they’ll thrive in the changing VC landscape. World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and Avlok Kohli on Twitter at @avlok.

Elad Gil is a prolific angel investor and advisor whose early investments include AirBnb, Coinbase, Pinterest, Stripe, and Square. He’s also the founder of Color Health and author of the bestselling book High Growth Handbook.Elad and Auren discuss the challenges and opportunities for startups in the emerging AI technology landscape, particularly in comparison to incumbent companies. Elad breaks down what he’s learned as an angel investor and provides some non-generic advice for making good early-stage investments. Auren and Elad also discuss fundraising and operating in lean times, the potential for life extension drugs, and why the biotech market is so fragmented. World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and Elad Gil on Twitter at @eladgil.

Johnathan Bi is the host of a fantastic seven-part lecture series on the work of philosopher René Girard. He’s also a member of the founding team at Opto Investments. Auren and Johnathan discuss some of the fundamental concepts in Girard’s philosophy and how they apply to startups, venture capital, and life more broadly. They break down physical vs metaphysical desire, the power of self-delusion, and Girard's concept of zero-sum and negative-sum human interactions.Johnathan explains what to make of Girard’s apocalyptic thoughts on the future of humanity, and makes some useful recommendations for using mimetic theory to improve your life. World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcastsYou can find Auren Hoffman on Twitter at @auren and Johnathan Bi on Twitter at @JohnathanBi.

Nicole Perlroth was the New York Times’ lead cybersecurity reporter for over a decade. She’s an advisor to the Department of Homeland Security’s Cybersecurity Advisory Committee and the author of the bestselling book This Is How They Tell Me The World Ends.Auren and Nicole discuss the global cyber landscape— which countries have the strongest hacking capabilities, how Ukraine has changed cyber warfare, and where the US stacks up against its adversaries. Nicole also shares insights on personal opsec and recounts her experience tracking down a potential leaker behind the Shadow Brokers hack of the NSA. World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcastsYou can find Auren Hoffman on Twitter at @auren and Nicole Perlroth on Twitter at @nicoleperlroth.

Sigal Mandelker served as Under Secretary of the Treasury for Terrorism and Financial Intelligence from 2017 to 2019. She’s currently a general partner at Ribbit Capital, which invests in fintech companies. Sigal and Auren discuss how sanctions actually work and what makes them effective. Sigal explains how the US’s role in the global financial system could change as new financial technology evolves. They also discuss how the government should work with the private sector, why crypto regulation has moved so slowly, and where the US is starting to look to other countries for regulatory leadership. World of DaaS is brought to you by SafeGraph & Flex Capital. For more episodes, visit safegraph.com/podcastsYou can find Auren Hoffman on Twitter at @auren and Sigal Mandelker on LinkedIn. 

Jonathan Greenblatt is the CEO of the Anti-Defamation League. Prior to leading the ADL, he was the founder of Ethos Brands, VP of Global Consumer Products at Starbucks, and Director of the Office of Social Innovation during the Obama administration. Auren and Jonathan discuss the role of technology in amplifying hate and extremism in society, and what tech companies and regulators should do about it. Jonathan breaks down how Section 230 could be reformed and how tech companies should approach moderation. They also discuss what the boundaries of free speech, comedy and anonymity should be on the internet. Jonathan gives an overview of the ADL’s research and the unparalleled data they have on extremism in the US. He shares insights from the ADL’s nearly 100 years of public opinion polling and puts the most recent figures in historical context. World of DaaS is brought to you by SafeGraph. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and‍ Jonathan Greenblatt on Twitter @JGreenblattADL.

Dr. Jonathan Levin is the Dean of the Stanford Graduate School of Business. He’s the winner of the 2011 John Bates Medal, and an expert in market design, game theory, and industrial organization. Auren and Jon discuss how Stanford GSB, one of the most selective schools in the world, thinks about finding talent. Jon breaks down the non-obvious ways universities foster innovation, and how that path of research differs from the private sector. They also discuss whether or not hedge fund managers are overcompensated, what datasets could improve public policy, and what kind of hard and soft skills are the most important today. World of DaaS is brought to you by SafeGraph. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and‍ Jon Levin on LinkedIn or at the Stanford Graduate School of Business. 

Dr. Nir Barzilai discovered the first “longevity gene” in humans and pioneered key research around the biology of aging. He’s the founding director of the Institute for Aging Research at the Albert Einstein College of Medicine in New York and the author of the book Age Later. Nir and Auren discuss the most promising studies and treatments in the field of anti-aging research and break down the major takeaways from Nir’s seminal studies on centenarians— why they live longer, and what the rest of us can learn from them. Nir also explains the role of genetics vs. environment in longevity and makes some data-backed recommendations for anyone who wants to live a longer, healthier life. World of DaaS is brought to you by SafeGraph. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and‍ Nir Barzilai on Twitter @NirBarzilaiMD.

Tony is a retired 4-star US Army General and was the commander of the US Special Operations Command from 2016 to 2019. During his 35-year military career, he played a key role in numerous high-profile operations, including the mission that resulted in the death of Osama bin Laden. He’s currently a partner at Lux Capital.Auren and Tony discuss what we’ve learned from the war in Ukraine and which countries are the strategic winners and losers of the conflict. Tony has a clear, nuanced view of Russia’s strengths and weaknesses and explains how the U.S. should be positioning itself against China.  Auren and Tony also break down how AI should be implemented in military technology, whether NATO is still relevant, and which of the US’s major weapons systems are obsolete.World of DaaS is brought to you by SafeGraph. For more episodes, visit safegraph.com/podcasts.You can find Auren Hoffman on Twitter at @auren and‍ Tony Thomas on Twitter @TonyT2Thomas.