JAMA Cardiology Author Interviews

Special edition of the JAMA Editor's Summary featuring the JAMA Network articles published at the 2025 European Society of Cardiology Congress. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, with JAMA Executive Editor Gregory Curfman, MD, JAMA Senior Editor Philip Greenland, MD, and JAMA Cardiology Editor Robert O. Bonow, MD, MS. Related Content: Remote Screening for Asymptomatic Atrial Fibrillation Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation Systolic Blood Pressure and Microaxial Flow Pump–Associated Survival in Infarct-Related Cardiogenic Shock Helicobacter pylori Screening After Acute Myocardial Infarction Physiology-Guided Complete Revascularization in Older Patients With Myocardial Infarction Fractional Flow Reserve–Guided Complete vs Culprit-Only Revascularization in Non–ST-Elevation Myocardial Infarction and Multivessel Disease Transcatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction Bivalent RSV Prefusion F Protein–Based Vaccine for Preventing Cardiovascular Hospitalizations in Older Adults High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults Risk of Myocarditis or Pericarditis With High-Dose vs Standard-Dose Influenza Vaccine Clonal Hematopoiesis and Risk of New-Onset Myocarditis and Pericarditis Participation of Women in Cardiovascular Trials From 2017 to 2023 Prevalence, Determinants, and Time Trends of Cardiovascular Health in the WHO African Region

Frederick L. Ruberg, MD, a prominent figure at Boston University and the Amyloidosis Center, discusses the critical impact of transthyretin cardiac amyloidosis on older Black and Hispanic individuals with heart failure. The conversation reveals stark racial and age disparities in prevalence, particularly among men over 75. Ruberg emphasizes the need for improved diagnostic practices that consider gender and ethnicity differences. Early detection strategies and advancements in therapy also take center stage, highlighting the importance of family testing to combat this growing health issue.

Interview with Margaret Infeld, MD, MS, author of Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction: Follow-Up of the myPACE Trial. Hosted by Robert Bonow, MD. Related Content: Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction

Roxana Mehran, a leading cardiologist at Mount Sinai, discusses the crucial need for diversity in clinical trials. She emphasizes that inclusivity improves patient care and treatment outcomes. The conversation covers strategies to enhance representation, such as community engagement and effective recruitment methods. Mehran highlights the industry's role in fostering diversity and the positive impact of transparent data reporting. Ultimately, she underscores that diverse trial populations are essential for developing reliable medical practices.

Interview with Michael McDermott, MBChB, author of CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy: A Nested Substudy of the SCOT-HEART 2 Randomized Clinical Trial, and Pamela S. Douglas, MD, author of The Last Mile in Prevention—Can Coronary CT Angiography Help? Hosted by Ann Marie Navar, MD, PhD. Related Content: CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy The Last Mile in Prevention—Can Coronary CT Angiography Help?

In this engaging discussion, Sean J. Jurgens, an assistant professor at Amsterdam UMC and researcher at the Broad Institute, delves into the critical connection between atrial fibrillation and cardiomyopathy. He highlights findings from cohort studies showing that young patients often carry cardiomyopathy-associated gene variants, which could indicate a higher risk of heart failure. The podcast emphasizes the importance of genetic testing for early-onset AF, exploring its benefits, challenges, and the future of accessible genetic screening for patients and families.

Interview with Alexander C. Fanaroff, MD, MHS, author of Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation: Two Cluster Randomized Clinical Trials. Hosted by Ann Marie Navar, MD, PhD. Related Content: Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation

Interview with Thomas Gaziano, MD, author of Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa, and Daniel W. Jones, MD, author of Dietary Sodium- and Potassium-Enriched Salt Substitutes—The Tipping Point? Hosted by Ann Marie Navar, MD, PhD. Related Content: Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa Dietary Sodium- and Potassium-Enriched Salt Substitutes—The Tipping Point?

Barry A. Borlaug, a renowned cardiologist at the Mayo Clinic, and Jwan A. Naser, a first-year cardiology fellow, discuss the intriguing relationship between heart failure with preserved ejection fraction (HFpEF) and severe isolated tricuspid regurgitation. They highlight the surprisingly high prevalence of HFpEF in these patients, stressing the need for improved diagnostic methods. The conversation delves into the implications for patient management, advocating for a deeper understanding of underlying conditions like pulmonary hypertension and the role of left atrial function.

Paul L. Hess, MD, MHS, and Vincenzo B. Polsinelli, MD, delve into heart failure treatment protocols and their real-world implications. They discuss the importance of the Guideline-Directed Medical Therapy (GDMT) score, emphasizing its role in enhancing patient outcomes. The variability in treatment effectiveness across hospitals is scrutinized, revealing stark differences in mortality and rehospitalization rates. The duo advocates for stronger adherence to hospital-level guidelines as a means to improve care quality and reduce healthcare costs.