JAMA Cardiology Author Interviews

JAMA Network
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Jul 30, 2025 • 16min

Preserving and Promoting Clinical Trial Representativeness

Roxana Mehran, a leading cardiologist at Mount Sinai, discusses the crucial need for diversity in clinical trials. She emphasizes that inclusivity improves patient care and treatment outcomes. The conversation covers strategies to enhance representation, such as community engagement and effective recruitment methods. Mehran highlights the industry's role in fostering diversity and the positive impact of transparent data reporting. Ultimately, she underscores that diverse trial populations are essential for developing reliable medical practices.
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Jun 18, 2025 • 19min

CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy

Interview with Michael McDermott, MBChB, author of CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy: A Nested Substudy of the SCOT-HEART 2 Randomized Clinical Trial, and Pamela S. Douglas, MD, author of The Last Mile in Prevention—Can Coronary CT Angiography Help? Hosted by Ann Marie Navar, MD, PhD. Related Content: CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy The Last Mile in Prevention—Can Coronary CT Angiography Help?
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Apr 30, 2025 • 15min

Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation

In this engaging discussion, Sean J. Jurgens, an assistant professor at Amsterdam UMC and researcher at the Broad Institute, delves into the critical connection between atrial fibrillation and cardiomyopathy. He highlights findings from cohort studies showing that young patients often carry cardiomyopathy-associated gene variants, which could indicate a higher risk of heart failure. The podcast emphasizes the importance of genetic testing for early-onset AF, exploring its benefits, challenges, and the future of accessible genetic screening for patients and families.
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Mar 26, 2025 • 20min

Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation

Interview with Alexander C. Fanaroff, MD, MHS, author of Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation: Two Cluster Randomized Clinical Trials. Hosted by Ann Marie Navar, MD, PhD. Related Content: Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation
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Feb 5, 2025 • 18min

Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa

Interview with Thomas Gaziano, MD, author of Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa, and Daniel W. Jones, MD, author of Dietary Sodium- and Potassium-Enriched Salt Substitutes—The Tipping Point? Hosted by Ann Marie Navar, MD, PhD. Related Content: Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa Dietary Sodium- and Potassium-Enriched Salt Substitutes—The Tipping Point?
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Nov 6, 2024 • 11min

Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation

Barry A. Borlaug, a renowned cardiologist at the Mayo Clinic, and Jwan A. Naser, a first-year cardiology fellow, discuss the intriguing relationship between heart failure with preserved ejection fraction (HFpEF) and severe isolated tricuspid regurgitation. They highlight the surprisingly high prevalence of HFpEF in these patients, stressing the need for improved diagnostic methods. The conversation delves into the implications for patient management, advocating for a deeper understanding of underlying conditions like pulmonary hypertension and the role of left atrial function.
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Sep 25, 2024 • 15min

Heart Failure Medical Therapy Score and Clinical Outcomes

Paul L. Hess, MD, MHS, and Vincenzo B. Polsinelli, MD, delve into heart failure treatment protocols and their real-world implications. They discuss the importance of the Guideline-Directed Medical Therapy (GDMT) score, emphasizing its role in enhancing patient outcomes. The variability in treatment effectiveness across hospitals is scrutinized, revealing stark differences in mortality and rehospitalization rates. The duo advocates for stronger adherence to hospital-level guidelines as a means to improve care quality and reduce healthcare costs.
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Aug 28, 2024 • 20min

Prevalence, Cardiac Phenotype, and Outcomes of Transthyretin Variants

Luis R. Lopes, PhD, investigates the prevalence of transthyretin variants and their effects on cardiac health, revealing significant associations in a study of nearly 470,000 individuals. Senthil Selvaraj, MD, MS, MA, discusses a genotype-first approach to identify at-risk patients for amyloid conditions, aiming for better health interventions. They also tackle representation issues in genetic research and the necessity for equitable access to screening. Insights into these genetic variants underscore their crucial implications for cardiac outcomes and public health.
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Jul 31, 2024 • 20min

Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

Interview with Jagmeet P. Singh, MD, DPhil, author of Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure. Hosted by Kristen K. Patton, MD. Related Content: Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure
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Jun 12, 2024 • 18min

Postpartum Ambulatory Blood Pressure and New-Onset Hypertensive Disorders of Pregnancy

Dr. Alisse Hauspurg discusses the importance of monitoring postpartum blood pressure to reduce complications. The podcast explores blood pressure targets in pregnancy, addressing inequities in hypertensive disorders. Barriers in postpartum hypertension monitoring are discussed, emphasizing the need for extended care and strategies to ensure access for individuals with hypertensive disorders.

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