JAMA Cardiology Author Interviews

JAMA Network
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Aug 28, 2024 • 20min

Prevalence, Cardiac Phenotype, and Outcomes of Transthyretin Variants

Luis R. Lopes, PhD, investigates the prevalence of transthyretin variants and their effects on cardiac health, revealing significant associations in a study of nearly 470,000 individuals. Senthil Selvaraj, MD, MS, MA, discusses a genotype-first approach to identify at-risk patients for amyloid conditions, aiming for better health interventions. They also tackle representation issues in genetic research and the necessity for equitable access to screening. Insights into these genetic variants underscore their crucial implications for cardiac outcomes and public health.
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Jul 31, 2024 • 20min

Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

Interview with Jagmeet P. Singh, MD, DPhil, author of Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure. Hosted by Kristen K. Patton, MD. Related Content: Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure
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Jun 12, 2024 • 18min

Postpartum Ambulatory Blood Pressure and New-Onset Hypertensive Disorders of Pregnancy

Dr. Alisse Hauspurg discusses the importance of monitoring postpartum blood pressure to reduce complications. The podcast explores blood pressure targets in pregnancy, addressing inequities in hypertensive disorders. Barriers in postpartum hypertension monitoring are discussed, emphasizing the need for extended care and strategies to ensure access for individuals with hypertensive disorders.
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May 15, 2024 • 23min

Osteosarcopenia and Mortality in Older Adults Undergoing Transcatheter Aortic Valve Replacement

Jonathan Afilalo, an expert in osteosarcopenia and its effects on older adults, delves into the critical role of frailty assessments in patients undergoing transcatheter aortic valve replacement (TAVR). He advocates for objective testing over subjective methods to enhance patient evaluations. The concept of osteosarcopenia is introduced, emphasizing the integration of muscle and bone health in frailty assessments. Afilalo also discusses how AI advancements in CT scans improve body composition evaluation, and he highlights the significant impact of osteosarcopenia on mortality rates in older TAVR patients.
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Apr 17, 2024 • 19min

Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction

Cardiologist Sanjiv J. Shah discusses atrial shunt device effects on heart failure patients. Topics include patient selection, risks, phase two trials with Corvia medical device, pivotal reduce LAP2 trial results, long-term echocardiographic findings, and future possibilities of inter-atrial shunt devices in heart failure treatment.
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Mar 27, 2024 • 17min

A Revised Definition of Left Bundle Branch Block Using Time to Notch in Lead I

Gaurav A. Upadhyay, MD, and Jeremy S. Treger, MD, PhD discuss a revised definition of left bundle branch block using time to notch in lead I. They explore challenges in defining LBBB, study conduction system pacing, introduce a new criterion for diagnosis, emphasize measuring notches in lead I, and stress the importance of ECGs in diagnosing cardiac conditions.
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Feb 21, 2024 • 21min

Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV

Discussion on the effects of pitavastatin on coronary artery disease and inflammatory biomarkers in individuals with HIV. Insights on risk reductions, plaque characteristics, and inflammatory markers. Exploration of statin therapy on plaque composition and perivascular inflammation in coronary artery disease. Considerations for initiating statin therapy in HIV patients amidst increased ASCD risk and polypharmacy challenges.
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Nov 15, 2023 • 22min

Effect of Tafamidis on Cardiac Function in Patients With Transthyretin Amyloid Cardiomyopathy

Exploring the impact of Tafamidis on cardiac function in patients with transthyretin amyloid cardiomyopathy, including insights on early treatment benefits, drug efficacy, and echocardiography effects. Discussion on the positive impact of Tafamidis in halting disease progression and improving cardiac function. Importance of assessing left atrial function in echocardiographic data collection and future treatments for transthyretin cardiomyopathy.
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Oct 25, 2023 • 21min

Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction

Divaka Perera and Julio A. Panza discuss viability testing and outcomes of revascularization in patients with ischemic ventricular dysfunction. They compare different trials and assess the role of viability assessment in determining appropriate treatment approaches. The chapter also explores the differences between contemporary medical therapy and older observational literature, highlighting the revolution in medical therapy's impact on trial comparisons.
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Sep 27, 2023 • 18min

Prevalence and Overlap of Cardiac, Renal, and Metabolic Conditions in US Adults, 1999-2020

Interview with Muthiah Vaduganathan, MD, MPH, and John W. Ostrominski, MD, authors of Prevalence and Overlap of Cardiac, Renal, and Metabolic Conditions in US Adults, 1999-2020. Hosted by Sadiya Sana Khan, MD, MSc. Related Content: Prevalence and Overlap of Cardiac, Renal, and Metabolic Conditions in US Adults, 1999-2020

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