00:46 Artemis 1 is go!NASA’s Artemis 1 mission has successfully reached Earth orbit. After weeks of delays and issues, and a nail biting launch, the rocket marks the first step in a new era of moon exploration, with plans to test a new way to return astronauts to the moon. We caught up with reporter for all-things-space, Alex Witze, for the latest.News: Lift off! Artemis Moon rocket launch kicks off new era of human exploration10:06 Research HighlightsThe unlevel playing field in women’s football, and domed structures provide evidence for a biological origin of stromatolites.Research Article: Okholm Kryger et al.Research Article: Hickman-Lewis et al.12:39 A mechanistic link for an Alzheimer’s geneAlzheimer’s disease is a form of dementia that affects millions of people every year. Whilst the biggest risk factor of late-onset Alzheimer’s is age, there are a number of genes that have been implicated. How exactly these genes underpin this disease is unclear, but new research may now reveal how one of them does so, by affecting the myelination of neurons. The authors hope this work may help uncover treatments for Alzheimer’s.Research Article: Blanchard et al.News and Views: Alzheimer’s risk variant APOE4 linked to myelin-assembly malfunction20:44 Updates from COP27The second week of the 27th UN Climate Change Conference is underway, as policymakers and scientists try to come together to tackle climate change. Flora Graham, senior editor at Nature is in Egypt at the conference and we caught up with her for the latest.News: ‘Actions, not just words’: Egypt’s climate scientists share COP27 hopesNews: Carbon emissions hit new high: warning from COP27Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

Kathleen Folbigg has spent nearly 20 years in prison after being convicted of killing her four children. But in 2018, a group of scientists began gathering evidence that suggested another possibility for the deaths — that at least two of them were attributable to a genetic mutation that can affect heart function. A judicial inquiry in 2019 failed to reverse Folbigg’s conviction, but this month, the researchers will present new evidence at a second inquiry, which could ultimately spell freedom for Folbigg.This is an audio version of our Feature: She was convicted of killing her four children. Could a gene mutation set her free? Hosted on Acast. See acast.com/privacy for more information.

00:49 Separating heavy water with molecular cagesHeavy water is molecule very similar to H2O but with deuterium isotopes in the place of hydrogen atoms. Heavy water is useful in nuclear reactions, drug design and nutritional studies, but it's difficult to separate from normal water because they have such similar properties. Now, a team have developed a new separation method using tiny molecular cages, which they hope opens up more energy efficient ways to produce heavy water.Research article: Su et al.News and Views: A molecular flip-flop for separating heavy water07:23 Research HighlightsHow dancers can feel the beat even when they can’t hear it, and how climate change might move desert dunes.Research Highlight: Dancers pick up the pace on a bass beat — even though it’s inaudibleResearch Highlight: Desert dunes pose more danger as Earth warms09:25 Monitoring bridge health using crowd dataBridges are vital pieces of infrastructure but their structural health is hard to monitor, requiring either sophisticated sensors or intense surveying by human engineers. Now though, researchers have utilized large amounts of smartphone accelerometer data to check the health of the Golden Gate Bridge. They hope this new technique can be used to effectively and cheaply monitor bridges around the world.Research Article: Matarazzo et al.Communications Engineering special issue: Resilient Infrastructure17:00 COP27 gets underwayThis week the 27th UN Climate Change Conference began, with world leaders, scientists and activists coming together to continue negotiations aimed at reining in global warming. Jeff Tollefson, senior reporter at Nature, joined us to talk about what’s been happening and what to expect, as the conference continues.News: Climate change is costing trillions — and low-income countries are paying the priceNews: As COP27 kicks off, Egypt warns wealthy nations against ‘backsliding’News: COP27 climate summit: what scientists are watchingSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

Companies are offering genetic tests of embryos generated by in vitro fertilization that they say allow prospective parents to choose those with the lowest risk for diseases such as diabetes or certain cancers. However, some researchers are concerned about the accuracy and ethics of these tests.This is an audio version of our Feature: The controversial embryo tests that promise a better baby Hosted on Acast. See acast.com/privacy for more information.

00:46 How flies can move their eyes (a little)It's long been assumed flies’ eyes don’t move, and so to alter their gaze they need to move their heads. Now, researchers have shown that this isn’t quite true and that fruit flies can actually move their retinas using a specific set of muscles, which may allow them to perceive depth. The team also hope that this movement may provide a window into some of the flies’ internal processes.Research article: Fenk et al.08:54 Research HighlightsHow the 80-year-old wreck of a sunken warship is influencing ocean microbes, and tracing an epilepsy-related gene variant back to a single person from 800 years ago.Research Highlight: A ship sunk during the Second World War still stirs up the seabedResearch Highlight: Families on three continents inherited their epilepsy from a single person11:11 Calls to mandate militaries’ emissions reportingThe eyes of the world will be focused on the UN’s upcoming COP27 conference to see what governments will pledge to do to reduce global emissions. But there’s one sector of countries’ carbon outputs that remains something of a mystery: the emissions of their militaries. We speak to Oliver Belcher, one of a group of researchers who have written a Comment article for Nature, calling for better reporting and greater accountability for these military emissions.Comment: Decarbonize the military — mandate emissions reporting19:07 Briefing ChatWe discuss some highlights from the Nature Briefing. This time: efforts from Middle East countries to cut greenhouse-gas emissions while still supplying fossil fuels; the upcoming demise of NASA’s InSight spacecraft; and new estimates for how long bacteria could survive on Mars.Nature News: The Middle East is going green — while supplying oil to othersNature News: NASA spacecraft records epic ‘marsquakes’ as it prepares to dieNew Scientist: Bacteria could survive just under Mars's surface for 280 million yearsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

When COVID-19 hit it didn't kill indiscriminately. In the US, being Black, Hispanic, or Native American meant you had a much greater risk of death than if you were white. And these disparities are mirrored across the world.In this episode we explore the complex tale behind this disparity. Throughout history, racism and biases have been embedded within medical technology, along the clinicians who use it. Cultural concepts of race have been falsely conflated with biology. The way medicine is taught, has reinforced flawed stereotypes. Disease itself, has been racialised. All of this adds up to barriers to care and worse health outcomes for many people, just because of the colour of their skin.Science and scientists have played an influential part in embedding such racism into medicine But by challenging received wisdom science too has the power to right wrongs, and work towards solutions.Read more of Nature's coverage of racism in science.Click here for our list of sources Hosted on Acast. See acast.com/privacy for more information.

In this episode:00:54 Siberian cave offers first-ever glimpse into Neanderthal familyBy analysing ancient DNA recovered from bone fragments found in two Siberian caves, researchers have identified a set of closely related Neanderthals: a father and daughter, as well as several other more-distant relatives. The work suggests that Neanderthal communities were small, and that females may have left their families to join other groups.Research article: Skov et al.News and Views: The first genomic portrait of a Neanderthal family09:14 Research HighlightsThe robotic falcon that frightens nuisance flocks, and how climate change could lead to power loss in low-income households.Research Highlight: Plagued by problem birds? Call RobotFalcon!Research Highlight: Loss of power looms for some families as climate changes12:32 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, assessing why women are cited less often than men in physics, and uncovering a long-lost star-map from ancient Greece.Science: Women researchers are cited less than men. Here’s why—and what can be done about itNature News: First known map of night sky found hidden in Medieval parchment Hosted on Acast. See acast.com/privacy for more information.

In this episode:00:45 Implanted brain organoids could offer new insights into diseaseBrain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals’ behaviour.Research article: Revah et al.News and Views: Human brain organoids influence rat behaviour09:20 Research HighlightsThe subtle timing shift that gives jazz music its ‘swing’, and why hydrogen power could be a cost-effective way to reduce heavy industry emissions in China. Research Highlight: What gives jazz its swing? A delay makes the differenceResearch Highlight: Hydrogen could help China’s heavy industry to get greener11:46 The exoskeleton boot that makes walking more efficientWearable robotic exoskeletons that aid or enhance movement are fast becoming a reality, but there are challenges to overcome — to work best these devices frequently require careful calibration for their user using specialist equipment and time in a lab. Now, a team have created exoskeleton boots that can help people walk faster and more efficiently by learning and adapting to the wearer’s gait as they walk. They hope that this approach could be used to develop personalised assistive devices in the future.Research article: Slade et al.Nature Video: The robot boot that learns as you walkSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode:00:46 A virtual chemical library uncovers potential antidepressantsCertain psychedelic drugs are of interest to researchers due to their promising antidepressant effects. To help speed up the discovery of molecules with useful properties, researchers have built a virtual library of 75 million compounds related to these drugs. This approach yielded two molecules that showed antidepressant properties in mice, but without the hallucinogenic activity of psychedelic drugs.Research article: Kaplan et al.Research Briefing: Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity08:25 Research HighlightsResearch suggests that ancient artificial island settlements were hubs of activity for society’s elite, and astronomers spot possibly the most luminous star ever observed.Research Highlight: Ancient DNA suggests that artificial islands were party spots for the eliteResearch Highlight: Scientists face down ‘Godzilla’, the most luminous star known10:42 Nobel NewsFlora Graham from the Nature Briefing joins us to talk about the winners of this year’s Nobel Prizes.Nature News: Geneticist who unmasked lives of ancient humans wins medicine NobelNature News: ‘Spooky’ quantum-entanglement experiments win physics NobelNature News: Chemists who invented revolutionary 'click' reactions win NobelEnter Nature’s ‘Scientist at Work’ photo competition, full details hereSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

The ongoing war in Ukraine has devastated the global economy, rocked geopolitics, killed thousands of people and displaced millions. Science too has been affected and the impacts on research are being felt more widely than just in Ukraine and Russia.In this episode of Nature's Takes we discuss the war's impact on publishing, international collaborations, climate change and energy, and the destructive impacts on scientists themselves. And as the war continues, we consider the future of science in the face of a new political climate. Hosted on Acast. See acast.com/privacy for more information.