Plain English with Derek Thompson

The Ringer
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98 snips
Mar 7, 2025 • 48min

Can a Vaccine Cure the World’s Deadliest Cancer?

Vinod Balachandran, a leading surgical oncologist at Memorial Sloan Kettering, discusses groundbreaking advancements in pancreatic cancer research. He explains how cancer, especially pancreatic cancer, cleverly disguises itself from the immune system. Excitingly, new mRNA-based personalized vaccines are showing promising results, with 75% of responding patients becoming cancer-free after three years. He also highlights innovations like an 85% accurate blood test for early detection, providing hope in the fight against this formidable disease.
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54 snips
Mar 4, 2025 • 58min

How AI Could Change the Future of Music

Mark Henry Phillips, a talented film and podcast composer, joins to discuss the rapid evolution of AI in music. The conversation dives into how AI tools can create songs, raising questions about the future of music composition. Phillips shares his experiences and worries that AI may replace human creativity. They explore the complexities of copyright law and the ethics surrounding AI-generated music. Ultimately, the discussion challenges our understanding of inspiration versus imitation in art and creativity.
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465 snips
Feb 28, 2025 • 60min

The End of Reading

This engaging conversation features Rose Horowitch, an Atlantic staff writer, and Nat Malkus, a scholar focused on education policy. They delve into the alarming decline of reading in America, noting a drop in leisure reading by half this century and concerning literacy scores for younger students. The guests examine how societal shifts towards multimedia are impacting critical thinking and argue for the importance of deep reading in fostering analytical skills. They also discuss proactive measures educators are taking to reignite a passion for reading among students.
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174 snips
Feb 25, 2025 • 55min

'How Progressives Froze the American Dream' (Live)

Yoni Appelbaum, the deputy executive editor of The Atlantic and author of 'Stuck,' discusses the stagnation of the American economy and housing market. He highlights the paradox of low unemployment yet declining hiring rates, revealing how many are working but few are hiring. Yoni outlines the challenges first-time homebuyers face with high interest rates and the record median age of 38. He also addresses the significant drop in migration and how progressive policies have altered the American Dream, ultimately limiting social mobility and opportunities.
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120 snips
Feb 21, 2025 • 1h 3min

Plain History: The Astonishingly Successful Presidency of James K. Polk

Walter Borneman and Robert Merry, both accomplished authors on James K. Polk, dive deep into the surprisingly successful presidency of this often-overlooked leader. They explore Polk's bold goals, such as acquiring Oregon and California, and the complexities of the Mexican-American War. Discussions range from the political landscape of 1844 to the fervor of Manifest Destiny. With tantalizing insights, they assess the transformative impact of Polk’s presidency on American expansionism and identity, illustrating the gap between his achievements and modern perceptions.
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173 snips
Feb 18, 2025 • 1h 2min

The Trump-Musk Doctrine: F-ck Around and Find Out

In this discussion, Michael Geruso, an economics professor specializing in healthcare policy, and Tim Layton, a healthcare economics expert from UVA, delve into the chaos of recent federal government changes, highlighting Musk's controversial tactics. They unpack the inefficiencies in healthcare spending, particularly within Medicare Advantage, and the staggering amounts lost to waste and fraud. The guests emphasize the dire need for a reconstruction of federal aid programs, particularly in health care, while critically assessing the ethical implications of current practices.
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211 snips
Feb 14, 2025 • 1h 7min

Is There a Scientific Case for Believing in God?

Ross Douthat, a New York Times columnist and author of 'Believe: Why Everyone Should Be Religious', dives deep into the changing landscape of faith in America. He discusses his own religious journey and how societal attitudes toward belief have shifted. The conversation touches on the scientific case for God's existence and the emotional drawbacks of that logic. Douthat also argues for the benefits of faith in fostering community and exploring existential questions, while reinterpreting the relevance of Christianity in modern life.
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36 snips
Feb 11, 2025 • 55min

Fraud, Scandal, and Failure in the Fight Against Alzheimer's Disease

Charles Piller, author of 'Doctored,' exposes the dark realities in Alzheimer's research, revealing how esteemed scientists faced allegations of data manipulation. He shares the rise and fall of the controversial drug simufilum, initially thought to reverse memory loss. Piller discusses the historical amyloid hypothesis and its limitations, alongside the challenges of scientific integrity and groupthink in the field. Lastly, he emphasizes the need for renewed trust in scientific institutions amidst growing concerns over fraud and stagnation in effective treatments.
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551 snips
Feb 7, 2025 • 1h 10min

The Energy Story of the Moment: The Unstoppable Rise of Solar Vs. the Unmovable Demand for Global Fossil Fuels

Nat Bullard, an independent energy analyst and author, shares insights into the complex landscape of global energy. He reveals that despite the rise of solar and battery technologies, fossil fuel demand remains high, with coal and oil production hitting record levels. The discussion highlights the unexpected resilience of energy sources like wood, while addressing the challenges of a green energy transition. Bullard emphasizes the potential of solar energy to mitigate climate change despite its competition with fossil fuels, painting a messy yet hopeful picture of the future.
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326 snips
Feb 4, 2025 • 1h 1min

The 5 Types of Wealth

In this engaging discussion, Sahil Bloom, author of 'The 5 Types of Wealth', shares his insights on redefining wealth beyond mere finances. He delves into concepts like time wealth, emphasizing the freedom to control schedules, and social wealth, which highlights the importance of deep relationships in an increasingly isolated world. Bloom also tackles the challenges of building authentic connections and aligns career choices with personal passions for a more fulfilling life. His wisdom encourages listeners to prioritize meaningful interactions and the true essence of well-being.

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