The Melanie Avalon Biohacking Podcast

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/skin6:25 - What Treatments Does Rachel Personally Use?7:45 - Dermal Rolling/Facial Stimulation10:15 - Collagen13:10 - Mixing & Matching Your Supplements14:45 - What Products Does Skin Truly Need?15:50 - Blue Light's Effect On Skin17:15 - Do I Need A Morning And Nighttime Routine?19:45 - Outdated Recommendations From Clinicians25:05 - Wearing Sunscreen26:45 - What About Sun Exposure For Vitamin D?29:00 - Supplements For Oxidative Stress29:50 - Better Sunscreen Products32:05 - Retinol36:35 - Retinoid Reaction Phase36:45 - Skin Cell Turn Over 41:30 - Puffiness In The Face And Under-eye Bags47:40 - Self Lymphatic Drainage48:30 - Measuring Inner Age49:55 - Improving Neck Skin; Tightening And Smoothing53:45 - Surgical Interventions54:35 - Debunking The "Natural" Movement57:20 - Injectables58:10 - Dermal Fillers1:01:50 - Biohacking Resources To Protect Your Skin1:09:45 - Venus TreatmentsGet 15% Off A One-On-One Consultation With The Coupon Code MelanieAvalon15 At rachelvarga.ca/get-started!1:11:00 - The Future Of Anti-Aging Technology

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/sugar1:55 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:10 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon8:45 - Dr. Jacoby's Background10:45 - What Are Our Nerves?15:55 - The Biochemical Pathway For The Autonomic Nervous System16:45 - Is The Damage Mechanical Or In The Electrical Signaling18:20 - Polyol Pathway18:55 - Maillard Reaction (Advanced Glycation End-Products)20:45 - Asymmetric Dimethylarginine22:40 - MS And Alzheimer's Connection To Sugar26:45 - Differences In Opinion On Sugars Effect On Nerves28:20 - The Way Sugar Damages The Heart30:40 - Autism34:45 - COVID19 And Sugar35:50 - Pregnancy And Glucose39:25 - Metformin40:35 - Poly-Pharmacy43:00 - Berberine47:15 - High Carb Low Fat49:40 - Can We Live On Just Fat?55:20 - Competition Of Vitamin C And Glucose In The Body (Ascorbate Competition Theory)1:00:35 - Fruit1:02:20 - Damage To The Olfactory Nerve1:04:40 - Gallbladder Diet1:08:45 - The Benefits Of Wine On ArteriesDRY FARM WINES: Low Sugar, Low Alcohol, Toxin-Free, Mold- Free, Pesticide-Free, Hang-Over Free Natural Wine! Use The Link dryfarmwines.com/melanieavalon To Get A Bottle For A Penny!1:11:05 - The Vagus Nerve1:15:00 - Medicinal Signaling Cells1:16:40 - Dietary Recommendations

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/keto2:20 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:30 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon8:10 - The Importance Of The History Of The Keto Movement And Other Topics9:30 - Investigating The Salt-Hypertension Hypothesis13:05 - The Way Doctors Treat Patients15:05 - The Mistake In Obesity Research16:15 - Recapping The History: Are We Looking For Causation Or Correlation?17:40 - Pathological Science19:55 - Constitutional Hypothesis Of Obesity22:50 - What Our Genes Determine26:20 - Genotypes And Phenotypes29:45 - Metabolic Fitness Vs. Body Size32:40 - Transitioning From A Traditional Diet To A Western Diet33:05 - The Pima Indigenous Tribe36:35 - What Does Insulin Do?41:30 - Rising Insulin In The Morning42:10 - Insulin Resistance42:40 - Insulin As Fuel Partitioning45:00 - Blood Glucose Content Throughout The Day47:15 - The Conversion Of Carbs To Fat50:55 - The Storage Of Fat Vs Carbohydrate51:40 - The Glucose Fatty Acid Cycle53:00 - The Insulin-Carb Hypothesis55:00 - The Reason We Gain Weight57:30 - The Fat Tissue In Obese People58:40 - "Some Of Us Fatten Easily, And Some Of Us Don't"1:01:25 - Insulin Dysregulation1:02:45 - Starving The Fat Cells Of Fat1:05:00 - HFLC VS HCLF1:09:25 - Transitioning Out Of Low Fat Diets1:10:50 - Misconceptions About Fat And Insulin1:19:25 - Measuring Insulin And Fatty Acids In The Blood1:21:00 - Hormonal Dysregulation Of Fat Storage1:22:40 - Hormones Vs. Excess Energy Intake1:26:00 - Hormones And Enzymes Responding To The Types Of Food You Eat1:26:45 - The Dichotomy Inside The Obesity Discussion1:33:10 - A Hack For A Plateau In A HFLC Diet1:35:50 - The Other Side Of The Hack1:37:25 - The Downside Of Insulin Therapies On T1D1:39:30 - Vintage Fats & The Idea Of Food As Medicine1:42:05 - What Will It Take For Society To Change?1:42:45 - Doctors Burning Out In The Current Medical System1:43:25 - The Plant-Based Argument 

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/waterGo To Melanieavalon.com/lite And Use The Coupon Code MelanieAvalon for $20 Off Your Order3:40 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!3:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon9:15 - Dr. Collin's Background12:10 - Diet And Cancer17:10 - Living With Cancer Vs Killing It18:10 - Metabolism Of Cancer 21:40 - The Correlation Of Depression In African Americans And Poor Health Metrics 23:30 - What Is Deuterium?27:40 - The Deuterium Component Of Food29:20 - Making Energy From Food With Nanomotors35:25 - Levels Of Deuterium In Water And Ice Over Time37:35 - Origins Of Mitochondria 39:55 - Deuterium And The Microbiome41:30 - Difference Between Hydrogen In Food Vs Water45:50 - The Weight Of Energy47:50 - What Are Our True Water Needs?55:30 - The Cooling Nature Of Water57:30 - The Body's Use Of Water58:30 - Cellular Communication1:00:00 - How Is Deuterium Measured, And What Should Our Levels Be?1:04:10 - The Average Deuterium Levels And How To Deplete It Appropriately1:06:30 - The Center For Deuterium Depletion1:08:00 - The Relationship Of Deuterium To All Parts Of Society1:11:45 - The Ketogenic Diet1:11:50 - The Deuterium Depleted Diet1:19:35 - Oxygenated Water1:22:20 - Managing Deuterium Levels With Light Therapy1:25:50 - Deuterium Depleted Water Protocol1:29:30 - Metabolism With Breathing Exercise1:31:10 - Where To Buy:1:32:30 - Who Should Buy?1:35:00 - Metformin And BerberineGo To Melanieavalon.com/litewater And Use The Coupon Code MelanieAvalon for $20 Off Your Order

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/metabolical2:10 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:20 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon8:10 - Dr. Lustig's Background10:10 - What Is Processed Food?12:40 - The Nova System (Classes Of Processing)14:45 - Class 4 Ultra Processed Food 16:50 - The Diet Debate18:20 - Leaky Gut19:25 - Could The Microbiome Adapt To Processed Food?23:55 - What's Better: Quality Food Or Fasting? 28:10 - NAFLD29:40 - Liver Fat & Metabolic Disease32:40 - Visceral Fat And Clinical Depression34:40 - Burning Liver Fat With Fasting37:20 - Which Comes First: Insulin Resistance Or Weight Gain?42:40 - Overproducing Insulin And Blocking Leptin43:50 - The Role Of Personal Responsibility46:10 - De Novo Lipogenesis With Carb Intake46:55 - The Role Of Choline 47:55 - Is Over-Processing Food A Moral Hazard50:30 - Health Insurance 51:10 - The Immoral Hazard51:50 - Commercialization Of Organics And Whole Food54:05 - Pesticides 54:45 - Labeling Processed Foods As Toxic 57:45 - The Real Disease; The 8 Pathologies1:00:35 - Low Fiber High Sugar 1:01:20 - Fixing The Problem 1:03:20 - Research With Fiber And CGM1:04:35 - UCSF Soda Ban1:06:40 - Expanding The Soda Ban 1:07:45 - GRAS List 1:10:15 - Removing Items From The GRAS List1:11:40 - Addictive Foodrobertlustig.commetabolical.com

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/intuitivefasting2:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!3:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon8:40 - Will's Background12:30 - The Controversy 15:25 - The Problems With Intuitive Eating19:10 - The Insulin Resistance Inflammation Spectrum23:50 - Can You Intuitively Eat Processed Foods?25:00 - Who Is Intuitive Eating/Fasting For?27:40 - Gaining Metabolic Flexibility29:05 - Healthy Control And Food Peace30:50 - The Evolution Of Fasting In Culture31:20 - How Does Fasting Become Intuitive?34:00 - Using Food And Fasting As A Mindfulness Practice36:25 - Teaching Intuitiveness39:00 - Fasting In Spiritual Tradition41:00 - What Is Required For Change In Our Culture?46:00 - Transparency In Industry46:35 - Plant-Based Vs Animal Inclusive Diets And Food Labeling54:00 - Nutritional Ketosis55:25 - Being Able To Pivot And Being Comfortable In Evolving57:45 - The Power Of The Microbiome59:40 - Intestinal Gluconeogenesis1:03:00 - Tea1:07:30 - Tea's Effect On Insulin

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/wahls2:00 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon7:30 - Dr. Whals' Story11:30 - Multiple Sclerosis14:15 - Myelin and Mitochondria15:05 - Myelin Dysfunction15:50 - Mitochondrial Strain In Autoimmune Diseases17:35 - Supplement Support20:30 - Electrical Stimulation For Muscle Growth23:40 - Muscle Atrophy In MS24:05 - The Shift Of Metabolism 24:50 - Diseases Of Insulin In MS Patients27:20 - Insulin Sensitivity In Astronauts29:20 - Neuromuscular Electrical Stimulation Devices30:05 - E-Stim In Athletes31:45 - E-Stim In Bed Ridden Patients32:50 - Recovery With The Paleo Diet And Lifestyle40:25 - Clinical Trials On The Diet Protocol47:05 - Healing The Myelin49:40 - Remineralizing Teeth52:00 - The Timeline Of Accepting New Concepts In Science55:15 - Proving The Wahls Protocol56:50 - The Early Adopters 57:45 - The Importance Of Being Strict For The First 100 Days59:10 - Accidently Triggering New Autoimmune Disease1:02:40 - Working As A Family1:03:00 - Terry's Current Protocol1:05:05 - Longevity Genes

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/levelsSkip The (115,000 person!) Waitlist By Going To Melanieavalon.Com/LevelsCGM With The Coupon Code MelanieAvalon!2:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!9:25 - Casey's Background14:20 - What Is A CGM?20:50 - What Is The Levels Experience Like?21:20 - How Is The Prescription Accessible?23:10 - The Application Process25:15 - What Is It Measuring?26:20 - What Is Insulin's Role In The Interstitial Fluid?27:15 - How Accurate Is It?28:40 - The Highest Saturation Levels30:15 - CGM Compared To A Finger Prick And/Or A Lab Draw31:30 - Why The 14 Day Time Limit?33:00 - Recommendations For Placement 35:20 - Placing A Patch Over The Sensor35:50 - Night-Time Accuracy40:45 - What Is A Good Range? 48:10 - CRP (C-Reactive Protein) And Inflammation50:00 - The Negative Effects Of Glycation51:20 - Insulin Resistance53:30 - Metabolic Fitness54:40 - The Most Insulinogenic Foods55:50 - The "Area Under The Curve"1:00:00 - Reactive Hypoglycemia1:02:35 - How To Bring Back Carbs After HFLC1:10:15 - The Differences In Glucose Response Person To Person1:11:50 - Glucose Levels In A Diabetic Individual1:12:35 - The Influences On Insulin Resistance1:16:15 - Berberine1:16:50 - Glucose-Lowering Probiotics1:18:50 - Is 2 Weeks Enough Time To Learn Your Patterns?1:21:50 - Can Listeners Subscribe To Levels?1:23:30 - Using The App And The Zone Score1:27:00 - How The Zone Score Is Valuated1:28:10 - Updates To The App1:28:45 - Data Storage Of The Sensor1:31:00 - Calibration1:31:20 - The Bluetooth And EMF1:31:50 - The Difference Between Glucose Levels, HbA1c And Serum Fructosamine1:37:20 - Testing Gestational DiabetesSkip The (115,000 person!) Waitlist By Going To Melanieavalon.com/LevelsCGM With The Coupon Code MelanieAvalon!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/setpoint1:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!6:40 - Jonathan's Personal History11:35 - Why Do People Gain Or Lose Weight?13:10 - The Global Economic Impact Of Diabetes14:50 - What Happens With Calories That We Eat?16:45 - The Calorie Is A Measure Of Energy Alone18:00 - Why Does The Body Burn Or Store Calories?19:50 - Dietary Induced Thermogenesis20:00 - N.E.A.T. (Non-Exercise Activity Thermogenesis)23:20 - Perceived Rate Of Exertion24:20 - Eat Less, Move Less24:30 - What Is The Stress Response To A Crash Diet?25:10 - Long Term Outcomes Of Crash Dieting26:15 - Yo-Yo Dieting And The Extracellular Matrix27:00 - Defining The "Set Point"29:55 - How Do We Get Our Set Point? How Does It Change?33:00 - Obesity As A Disease State 34:00 - The Quality Of The Food We Eat35:00 - The Overconsumption Of Food36:40 - Hormone "Clogging"39:35 - Parabiotic Studies40:45 - The Communication Between Brain, Gut, And Hormones43:40 - The Genetic Component47;55 - The Pervasive Shame In Being "Over-Fat" In Society48:30 - SANESolution50:25 - Evaluating Foods On A Spectrum For Optimal Health52:10 - The SANE Food Groups55:30 - What About Lower Fat Or Lower Carb?57:05 - Metabolic Conditioning59:10 - The Randall Cycle 59:25 - The Myth Of Exercise1:02:50 - Mechanical Removal Of Fat Cells

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/ketolies2:30 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:45 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon8:00 - Marty's Personal Story9:55 - Misconceptions Around Controlling Diabetes11:55 - Insulin's Role In Each Type of Diabetes13:45 - Understanding The Lack Of Insulin: T1D Vs. T2D14:30 - Diabulimia15:44 - Basal Insulin 16:25 - Insulin In Fat Storage And Release17:15 - Insulin Is Anti-Catabolic18:30 - Non-Insulin Mediated Glucose Uptake19:00 - The Role Of Insulin In Fat Storage19:40 - Oxidative Priority20:55 - Does Fat Illicit A Fat Response?22:05 - Can You Take In Too Much Fat?23:50 - More Fat Over The Long Term Leads To More Insulin24:50 - Burning The Energy In Your Body26:55 - Consuming Bulletproof Coffee And MCT Oil, Etc28:40 - Experiments With C8 MCT31:05 - Factors That Effect Fatty Acid Esterification32:00 - The Idea Of Burning Fat Exclusively In The Absence Of Carbs34:00 - Burning Fat In The Krebs Cycle33:30 - Energy Toxicity And Ketone Levels 39:00 - Is Burning Ketones "Cleaner"?39:40 - The Different Types Of Ketones45:50 - Low Glucose And High Breath Ketones 47:00 - Nutritional Ketosis51:20 - The Real Goal Of Low Carb Diets52:25 - Charts Of Energy Distribution 54:20 - Long Term Fasting55:10 - What Has Caused The Obesity Epidemic?57:00 - Lack Of Nutrient Density In Our Food System59:00 - The Bliss Point Of Fake Foods1:00:45 - Satiety1:02:00 - MUFA, PUFA, And Saturated Fat Satiety1:03:40 - Omega 3 Satiety1:06:45 - Micronutrient And Macronutrient Satiety Index1:08:25 - The Triage Theory1:09:15 - Is It Possible To Get All Nutrients From The Diet?1:25:35 - Taking Concentrated Supplements1:13:05 - Are Animal Products Less Depleted Of Nutrients?1:16:10 - Regenerative Agriculture1:17:20 - Vegan Vs. Carnivore1:18:50 - Carnivore As An Elimination Diet1:21:35 - High Blood Sugar In Keto And Carnivore1:22:35 - Gluconeogenesis Driving Insulin Resistance1:26:40 - Elevated Glucose Due To Gluconeogenesis1:27:45 - Chicken Or The Egg? Is Insulin Resistance Or Obesity First?1:28:15 - Insulin Resistance In Thin People Vs Obese People1:30:10 - Insulin Response From Food1:31:45 - Seasonal Eating1:34:45 - Checking Glucose Before Eating1:37:40 - Blood Sugar SetPoint1:38:40 - Eating With High Blood Glucose; A Hack1:39:40 - Using Berberine1:39:55 - Alcohol1:41:50 - Biggest Lesson1:43:20 - Data-Driven Fasting1:45:20 - Macros, Calories, And Nutrients