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The Melanie Avalon Biohacking Podcast

Latest episodes

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Jun 17, 2022 • 2h 3min

#150 - Dom D’Agostino: Ketogenic Diets, Exogenous Ketones, Measuring Ketosis, Long-Term Keto, Fasting & Caloric Restriction, Metabolic Flexibility, The Dawn Effect, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/domdagostino2:25 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:40 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon10:30 - NASA's NEMO12:50 - The Aquarius Habitat And Hyperbaric Effect17:55 - Performance Ketogenic Diet19:15 - CNS Oxygen Toxicity21:25 - Dom's Research Into The Ketogenic Diet 23:45 - Anti Seizure Drugs Vs Keto26:30 - What Makes Keto Beneficial?28:50 - Seizure Control With Other Low Carb Diets31:00 - Root Cause In Seizure34:00 - The Spectrum Of Ketosis35:30 - Becoming Fat Adapted37:20 - Higher Resting Blood Glucose On Keto38:00 - The Dawn Effect41:50 - Cryotherapy, Ketones, And Blood Glucose45:00 - Why Do We Enter Ketosis?48:30 - Acetyl CoA50:20 - Starvation And Metabolic Disorders That Prevent Ketosis55:10 - The Inuit56:30 - Long Term Ketosis58:40 - Is Chronic Ketosis Healthy?1:00:25 - Fat Adaptation Through Restricted Carbs Vs Restricted Dietary Fat1:04:40 - Ketones And Mitochondrial Uncoupling1:12:30 - Lactate1:15:20 - Ketones To Fuel The Brain1:18:00 - Strict Keto With Carb Cycling Vs Moderate Carb Keto1:24:15 - Ketone Bodies And Measuring Ketosis1:30:30 - Acetone On The Breath1:34:10 - Acetone For Anti Seizure Effects1:35:50 - Personalizing The Ketogenic Diet For Our Genetics1:38:15 - Exogenous Ketones Vs Endogenous Ketones1:40:40 - Salts Vs Esters1:44:10 - Can We Become 'Ketone Resistant'?1:45:55 - Chasing Ketones1:47:45 - 'Metabolic Memory'1:51:00 - Is Keto Pro-Cancer Or Anti-Cancer?1:55:00 - Pairing Keto With Cancer Treatments
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Jun 10, 2022 • 1h 59min

#149 - Chris Masterjohn: Achieving Ideal Nutritional Status, Dietary Recommendations & Requirements, How Omega-6s Resolve Inflammation, Vitamin Supplementation & Limits, Veganism Implications, Choline & Fatty Liver, Aspirin Benefits, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/chrismasterjohn2:25 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:40 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon12:30 - Chris' Start In Nutrition17:20 - Weston Price's Principals30:15 - Veganism32:30 - Longevity With Veganism37:00 - Creatine39:20 - Synthesizing Vitamins, Deficiencies, And RDAs47:20 - Niacin52:50 - Cravings Driving Food Intake56:00 - Supplement Toxicity1:03:30 - Liver As A Superfood1:07:30 - A Study Rats Unnatural Diet & Environment1:17:00 - The Derangement Of The Modern Palate1:22:20 - Choline & Fatty Liver1:32:00 - Is Choline Production Demand Driven?1:32:45 - High Dose Choline1:34:40 - Polyunsaturated Fats, EPA, DHA & Inflammation1:44:00 - The Balance Of Different Cell Types & Wound Healing1:52:30 - Resolution Of Healing1:54:45 - Omega-3s1:56:55 - Aspirin1:59:10 - NR Vs NMN
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Jun 3, 2022 • 45min

#148 - Dr. Michael Breus (Part 2): Biohacking Sleep, Morning Routines, Your Partner’s Habits, Blue Light, Red Light & NIR, Bedroom Temperature, Screens At Night, Melatonin, CBD, GABA, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/michealbreus3:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!3:20 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon11:45 - Who Benefits The Most From Good Sleep Hygiene?14:00 - Is There One Tip That's Better Than Other Tips?18:00 - The Morning Hacks For Great Sleep23:50 - What About "Bad Habits" That Still Work For You27:20 - Working Around A Partner's "Bad Habits"29:40 - Red Light And NIR Before Bed31:00 - Sleep Temperature33:10 - Social Interaction Situations Before Sleep35:10 - Tracking Sleep36:15 - Orthosomnia37:20 - Can You Hack Sleep Stages?38:50 - Mouth Taping40:00 - EMF 41:20 - Somavedic44:35 - Supplements: CBD, Melatonin, GABA, Etc.47:30 - Body Position While Sleeping48:55 - Sleep And Sex 
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May 27, 2022 • 1h 25min

#147 - Gin Stephens: Clean(ish), Home Environmental Toxins, "Greenwashing", Endocrine Disruptors & Obesogens, Food Additives, Helping The Family Make Changes, The Bucket Effect, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/cleanish2:30 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:45 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon14:00 - A Book For Everybody15:00 - Gin's Beginning In Fasting16:35 - Dietary Confusion20:35 - Lactase Persistence & Dairy21:35 - Can We Adapt To A Processed Diet?23:10 - Where Do You Start?29:40 - Seed Oils32:00 - The Connection Between Food Sensitivities And Behavior36:00 - Salicylates37:30 - Environmental Fumes41:05 - Generally Recognized As Safe (GRAS)43:00 - The Role Of How Chemicals Can Effect Fat Cells Or Weight Loss47:20 - Cosmetics48:30 - Transdermal Delivery50:20 - Labels And "Green Washing"53:40 - Fragrance Free Vs Unscented57:15 - The Home Environment1:00:15 - Using The Environmental Working Groups Rating Scale1:01:45 - Off-Gassing Furniture And Bedding1:03:00 - The Bucket Effect1:08:00 - Child Diagnonses1:09:10 - A Plan To Making Changes1:14:00 - Empowering Your Kids1:17:00 - Food And Nutrition1:21:00 - An 'Overflowing Bucket' Story 
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May 20, 2022 • 1h 21min

#146 - Dr. Rick Johnson: Fructose & Obesity, The Survival Switch, Salt & Weight Gain, Stimulating Fat Production, Uric Acid, The Polyol Pathway, Metabolic Syndrome, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/fructose2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon10:50 - Beginning Of Fructose Research14:30 - How Sugar Can Cause Weigh Gain Independently Of Caloric Intake17:30 - Leptin Resistance23:10 - Defining Glucose, Sucrose, And Fructose26:55 - "Tasteless" Mice28:00 - Craving Sugar 31:20 - 5 Great Tastes33:00 - Artificial Sweeteners34:00 - Blocking The Fructokinase In The Liver36:00 - How Fructose Tricks The Body42:10 - How Fructose Uses Glucose To Create Fat50:00 - Polyol Pathway51:40 - Stress & Dehydration53:50 - Salt1:00:30 - How Hibernation Mimics Metabolic Syndrome1:04:30 - Evolutionarily, Where Did This Start?1:07:45 - The Natural Fasting Cycle1:08:30 - The Role Of Fructose In The Cells, AMPK, And AMPD1:16:00 - What Happens When You Combine Starvation With The AMPK Pathway?1:21:00 - Starvation Mode1:24:30 - What About Whole Fruit? The Role Of Vitamin C
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May 13, 2022 • 1h 4min

#145 - Dr. Shamini Jain: Biofield Science, Energy Healing, The Placebo Effect, Quantum Physics, Distance Healing, Reiki, Ayurveda, TCM, Bio-Magnetic Fields, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/healingourselves2:00 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon12:00 - Shamini's Personal Story13:30 - Brain Changes Over Time14:35 - Reiki & Energy Healing17:10 - Similarities And Differences Across Religions19:20 - Healing Practices & Meditation25:30 - What's First; Top Down Or Bottom Up For Healing28:00 - Dynamic Communication Between Mind And Body29:00 - How Much Experience Do We Need To Get The Benefit In Healing Practices?32:00 - Breath Work34:40 - The Study Of Biofields36:30 - Animal Studies39:00 - How Does This Work?41:30 - The Quantum Perspective43:30 - Ayurveda And Traditional Chinese Medicine46:50 - The Placebo Effect52:40 - Placebo H.E.A.L.54:20 - Nocebo Effect1:01:00 - Distance Healing1:03:45 - Healing Touch
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May 6, 2022 • 1h 25min

#144 - Bill Tancer: Reframing Haters And Negative Reviews, Learning From Data Analysis, CGMs For Weight Loss, Predicting Glycemic Response, Healthy User Bias, Search Habits & Trends, Influencers, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/click2:15 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:30 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon10:35 - Bill's Background13:40 - Data Collection15:50 - What We're Searching On The Internet19:45 - What People Search Vs What We Admit To Searching24:00 - How To Interpret Data Correctly28:15 - Confirmation Bias In Algorithms29:00 - How Does The Internet Change Our Trends31:20 - Imperfect Information32:05 - Perfect Information33:00 - Perfect Information In Interpersonal Relationships32:30 - Takeaways From "Everyone's A Critic"38:40 - Chef's And Bad Reviews39:50 - Asking For Reviews And Earning Good Reviews43:30 - Reviews On Amazon47:20 - Influencers48:30 - Honesty In Influencing50:25 - False Hope Syndrome56:25 - Extreme Diets 58:00 - Lifestyle Changes And Intuitive Eating1:01:15 - Creating Signos1:05:00 - Diet-Heart Hypothesis And Cholesterol1:06:10 - Bill's First CGM1:07:45 - Data Analysis In Signos1:09:45 - Predictions In Glycemic Response1:15:45 - Intuition About What Will Spike Glucose1:16:50 - Bio-Individuality In Sucrose, Glucose, And Fructose Digestion1:18:10 - Enzymes, Cravings & Metabolic Syndrome1:19:45 - Is There Healthy User Bias In Signos Data
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Apr 29, 2022 • 1h 30min

#143 - Dr. Peter Kozlowski: Fiber & FODMAPs, Food Sensitivities, The Gut Brain Connection, SIBO Testing & Treating, Trauma & Health, Probiotics & Prebiotics, Heavy Metals & Mycotoxins, And More!

1:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon10:10 - Doc Koz's Personal Story14:45 - Root Cause Medicine18:00 - The Role Of Trauma In Health20:30 - Searching For Alternatives To Traditional Medicine21:25 - The Risk Of "Smaller" Traumas24:30 - Recommendations For Research And Self Diagnosis28:30 - The Gut-Brain Connection And Mental Health31:45 - Low Stomach Acid33:25 - The Microbiome35:25 - Fasting38:30 - Supplemental HCL42:00 - Testing And Treating44:00 - Hormones45:30 - SIBO50:05 - Refaxamin51:10 - Herbs To Treat SIBO53:50 - Berberine54:10 - Probiotics And Prebiotics59:20 - Fiber1:01:30 - FODMAPS1:05:10 - Part Two Diet1:07:20 - Mold & Heavy Metal Toxicity1:08:15 - Elimination Diets And Food Sensitivities1:14:30 - Shellfish1:15:15 - Celiac Disease1:18:30 - Twisty Colon1:20:00 - Candida1:24:15 - Compounding Medication1:24:55 - Thyroid1:30:15 - Can Trauma Be Stored In The Fat Cells?
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Apr 22, 2022 • 1h 56min

#142 - Dr. Eric Zielinski: Essential Oils Apothecary, Combating Chronic Disease Naturally, Hemp & CBD, Digestive Support, Depression & Anxiety, Immune Function, Anti-Inflammatory Lifestyle, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/apothecary1:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon15:30 - Dr. Eric's Journey Into Essential Oils23:35 - Chronic Disease27:30 - Essential Oils As Medicine31:40 - What Is An Apothecary?34:50 - Women As Healers In The Home43:00 - What Do You Have To Learn?45:50 - Everyday Use48:30 - The Female Audience51:50 - What Can Essential Oils Do, And What Role Can They Play In Helping Prevent Chronic Disease?51:30 - COVID55:50 - Is The Benefit Of Essential Oils In The Smell Alone?57:00 - Sneezing, Watery Eyes, Diarrhea1:01:30 - The Emotional Benefits Of Essential Oil1:03:20 - Bringing Back Smell And Taste After COVID1:05:20 - Getting Sick1:11:00 - Snacks1:12:15 - Tolerance And Addiction To Sweets And Fats1:20:20 - CBD1:32:15 - Metabolic Health And Weight Loss1:35:00 - Adaptogens1:38:20 - Fat Burning Roll On1:41:50 - Lime Oil1:46:20 - Reducing Toxic Burden1:47:00 - Fasting Of All Types1:53:30 - Building Your Own Haven
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Apr 15, 2022 • 1h 15min

#141 - Dr. David Perlmutter: Drop Uric Acid, The Cause Of Metabolic Syndrome, Salt & Obesity, Alcohol, Purines & Gout, Mitochondrial Dysfunction, Endogenous Fructose Production, High Blood Sugar & Blood Pressure, And More!

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/uricacid2:15 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon11:45 - Why Does Fructose Threaten Our Health?13:50 - Can We Evolve Out Of The Obesity Signaling Pathway From Fructose?20:20 - Triggering The Pathway21:20 - Orange Juice23:55 - The Historical Consumption Of Fructose25:45 - Depletion Of Energy In The Cell By Fructose Metabolism30:15 - AMPD34:05 - Neurological Effects Of High Uric Acid36:00 - Uric Acid's Role As An Independent Risk Factor In Mortality40:50 - Does Metabolic Syndrome Come With High Uric Acid Exclusively41:40 - Purines46:00 - Checking Uric Acid47:20 - "Normal Levels"48:30 - Recommended Sugar Consumption Per Day52:00 - Allopurinol 54:45 - Does Ketosis Create Uric Acid?1:00:10 - Cycling Keto1:03:30 - Healthy Mitochondria1:06:00 - Gender And Uric Acid1:09:20 - Endogenous Fructose Production1:11:15 - Why Is The Body Making Fat If It Feels Its Dehydrated?1:13:30 - The Evolution Of Storing Fat For Metabolic Water1:15:00 - Sodium In The Diet1:16:15 - Drugs That Elevate Uric Acid1:17:40 - Quercetin Daily

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