Angel Invest Boston

Angel Scale Biotech: Learn More   Growing new cartilage in your knees is a dream about to become reality. Listen to Ben Holmes, PhD, co-founder of Nanochon, to learn about his promising technology. Shoutout to Richard Meiklejohn of M2D2 for the introduction.    Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Ben Holmes What Problem Nanochon is Solving "... That's really what we're looking to do, is offer a solution that can be a much easier, much more cost-effective solution for providers, but also something that can really provide much better short and long-term outcomes for patients, and, ultimately, make the knee replacement obsolete..." The Solution: What it is, and How it Works "... We're seeing much better repair, and we're doing it with something that's an easy-to-use, off-the-shelf product..." What is I-Corps? Future Funding Plans Names and Numbers Ben's Entrepreneurial Journey Advice to the Audience   Topics: biotech, discovering entrepreneurship, founding story

Drew Madson, founder of Readlee, discusses how his startup offers an effective way to measure and remedy reading deficits among online learners. He shares the inspiration behind Readlee and its recent acquisition by Paper, the tutoring platform. The podcast also explores the importance of reading aloud, collaboration with strategic players in the education industry, and the potential impact of large language models on speech recognition and comprehension in education.

Angel Scale Biotech: Learn More   Tech founder David Kessler discusses his journey as an angel investor in companies such as CleanFiber, Wasabi, and Hilltop Bio.   Sponsored by Purdue University enrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces David Kessler "... This is like a very counterintuitive investment for angel investors, but it was angel-funded..." The Importance of Updates What Hilltop Bio Does "... This is why I want to create infrastructure to help the angels support these academic founders with connections..." Wasabi "... helping founders hone their messaging, hone their presentation..." "... Basically, the question is, what other ways of looking at the world are there and are you flexible enough to say that there are other ideas out there, and you may wind up pivoting into one of those..." How David Kessler Got into Angel Investing "... Start slow, start small, and don't invest alone..." Advice to the Audience   Topics: angel investing strategies, building wealth, product

Angel Scale Biotech: Learn More   Salvatore Viscomi, M.D. is CEO of Carna Health, a digital platform that is making it easier for patients with chronic conditions to do tests at home that would normally have to be done in the hospital.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Salvatore Viscomi What Carna Health is Solving "... We connect the device to our platform, we collect the data, we stage the disease, and then we share that information with the patient-provider..." "... The solution is really to bring the testing to the community, identify the 90% of people that don't know they have it, let them know they have it..." "... The devices on their own without connectivity and without a platform are really not a scalable solution for the type of programs that are needed to make an impact on these diseases ... The doctors are connected through a physician portal, and we identify all the people that are being screened..." Carna Health's Business Model "... We don't want our patients, necessarily, who are not feeling well, have medical conditions, to be exposed to other patients and potentially get infected..." "... One of the ways that Carna Health enables hospital home, is that it provides some of that testing in real-time, so patients don't need to go into a laboratory or phlebotomist..." Digital Twins: What Are They? Salvatore's Entrepreneurial Journey Advice to the Audience "... I think our system has been based on being very reactive to disease as opposed to prevention. The truth is that about 80% of longevity is determined by you and your environment and 20% by your genetics..."   Topics: biotech, discovering entrepreneurship, product, robotics/AI

Angel Scale Biotech: Learn More   Nick LaRovere and Matt Hawkins co-founded Pryzm.io seeking to simplify the process of buying a home via technology.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Nick LaRovere and Matt Hawkins What Pryzm.io is Solving "... Nick and I are both technical co-founders. We love building things, and so we're really excited to actually have our product in the hands of our early agent partners here in Boston..." "... We take what is previously only agent-facing tooling, and we flip it around so that the consumer can really take charge of their own transaction. They can be empowered to work autonomously..." The Importance of Renter's Insurance "... real estate is a very congested space from technology perspective. What Pryzm is really trying to do is be that foundational information layer that the rest of the real estate experience can evolve from..." "... at Pryzm we are very much aware of where the opportunity for technology to help automate that space is, to understand documentation, to summarize documentation, to frame it, or repurpose it in useful ways that are understandable by somebody who hasn't read a full mortgage before, and that is very much part of the Pryzm experience..." How Pryzm.io Came to Be "... To make not just the entire ecosystem, but especially that consumer, that person who's really the core, the crux of the transaction, to have a better experience..." Parting Thoughts to the Audience   Topics: co-founders, discovering entrepreneurship, founding story, robotics/AI  

Coach Jina Klapisch who helps Sal Daher keep off 100 pounds is our guest in this episode. Sal and Jina discuss how HMR clients are able to take off and keep off significant weight with no hunger or feeling of deprivation. Check out HMR Weight Loss and Lifestyle Coaching at: https://www.hmrnatick.com/about_us Highlights: ●  Sal Daher Introduces Jina Klapisch ●  What Sets HMR Apart From the Rest ●  How HMR Works ●  "... What you're doing here is helping people discover the things that are easy for them to do repeatedly and make them into habits, and not try to do stuff that's hard, impossible for them..." ●   Decision-Free ●   Sal's Diet Journey at the Age of Thirteen ●   Oprah and HMR ●    "... when you're trying to make a very big change in your life, whether it's quitting smoking or quitting drinking, or with food, you need to take a break from that substance ... so that you can see clearly as you lose this weight and start to really figure out who I am as an eater..." ●  How Your Environment Can Affect Your Weight ●   Outlive by Peter Attia MD ●    "... The first half mile that you walk every single day is the golden half mile. The first mile you walk is the golden mile. That is going to add years to your life..." ●   Advice to the Audience ●   Jina's Background ●    "... 80% of weight loss is keeping it off, the hard part..." ●   Jina's Parting Thoughts

After recording the full episode titled “Tech & Weight Control” I realized I left out some important technologies I use in making the shakes that support my keeping off 100 pounds. So, here’s a mini-episode with that staircase wit, as the French call it. Highlights: ·      Ninja Creami Ice Cream Maker ·      Ninja Bullet & Cuisinart Mini-Prep Plus Are Smaller & Cheaper Alternatives ·      Shaker Bottles Are Real Calorie-Savers ·      Acaia Digital Scale   Topic:              Healthy Aging Guest:             Sal Daher Title:                Staircase Wit: Shake Tech

Technology has long conspired against our health by making us fatter, more sedentary and sleepless. However, we can recruit tech as our ally in building healthy habits. Here is a review of the tech that is helping me keep off 100 pounds.   Highlights:   ·      Tech Can Make Us Less Healthy but It Can Be Good for Us Too ·      Getting Help in Weight Loss Is Really Powerful, You Can’t Do It Alone ·      MyFitnessPal App ·      Noom App ·      Fitbit Charge 4 Tracker + Fitbit App ·      WHOOP Band and App ·      Shoutout to the Great Products from Hoplark ·      Plenity, FDA-Cleared Weight Control Device (Does Not Act Systemically) ·      “I used it [Plenity] as an on-ramp for my HMR diet...” ·      Fitbod ·      Life Fitness Elliptical Cross-Trainer ·      NordicTrack Cross Country Exerciser ·      Tonal ·      Bowflex SelectTech ·      $19.99 Chin-up Bar from Amazon ·      Marathon Sports ·      PowerStep Arch Support ·      The Drive: Podcast with Peter Attia, M.D. ·      Huberman Lab Podcast ·      HMR: for When You Are Really Serious About Losing Weight Topic:              Healthy Aging Guest:              Sal Daher Title:                Tech & Weight Control

Angel Scale Biotech: Learn More   Getting enough sleep is important to Sal Daher’s effort to keep off 100 pounds. This short episode discusses how sleep connects with weight and how to improve sleep in support of weight control.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Why We Don’t Sleep Enough Markets & Technological Innovation Are to Blame but the Solutions Need to Come from Individuals and Voluntary Associations, not from Leviathan We Know We Need to Sleep More but the Cards Are Stacked Against It Why Is Sleep So Important to Weight Control? As We Age Our Need for Sleep Does Not Decline but Our Ability to Sleep Does Why I do Early Morning Exercises Outdoors – GoodLux Technologies Huberman Lab Podcast Offers Valuable Tips   Topic: Healthy Aging

Angel Scale Biotech: Learn More   Sal Daher, CFA discusses the role of exercise in his keeping off 100 pounds of body weight with no drugs and no surgery, just good habits for eating, exercising and sleeping. Listen for tips and for encouragement on building your exercise plan.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Why Exercise? How Much Exercise Do I need? Don’t Get Overly Ambitious – Start Slowly but Build Steadily Within Safe Limits Do Try to Get Out of Your Comfort Zone – Here’s Why Think You Can’t Exercise? Listen to These Stories Then, Tell Me You Can’t Exercise No Financial Stake in HMR, Just Immense Gratitude for How Much They Have Helped Me It Matters When You Exercise Short Bouts Build Up Do a Variety of Exercises Zone 2 / Zone 5 Training Exercise Has an Unexpected Side Effect for Me I’ve Never Regretted Exercising   Topic: Healthy Aging