

The Heart of Healthcare | A Digital Health Podcast
Massively Better Healthcare
🏆 #1 podcast in the Top 100 Health Tech All-time chartsJoin us every Monday for conversations with the biggest names in digital health. Hosted by digital health veterans Halle Tecco, Michael Esquivel, and Steve Kraus.Learn more and submit your ideas for the show at the Heart of Healthcare website.
Episodes
Mentioned books

Jan 26, 2026 • 42min
Building the Largest Health Data Ecosystem in the US | Datavant CEO Kyle Armbrester
Conversations about modernizing how clinical data moves and why healthcare still relies on fax and after‑the‑fact billing. Exploration of securing patient information against cyberattacks and tokenization as a path to safer data exchange. Discussion of scaling a national health data exchange and the incentives blocking value‑based care and better medical records.

14 snips
Jan 19, 2026 • 32min
Is Healthcare the Ultimate Test for AI? | Ankit Jain
Ankit Jain, co-founder and CEO of Infinitus Systems, shares his expertise on voice-based AI in healthcare. He reveals how AI is transforming high-stakes medical calls, emphasizing the shift from traditional communication methods like phones and faxes. Ankit predicts that while many health systems will attempt to build their own AI agents by 2026, most will revert to vendors by 2027. He also discusses potential risks, the importance of safety regulations, and how AI can ultimately enhance personalized care in the industry.

25 snips
Jan 12, 2026 • 36min
đź”® 2026 Digital Health Predictions | Annie Lamont
Annie Lamont, a veteran venture capitalist and co-founder of Oak HC/FT, shares her insights on the future of healthcare. She recounts the tough landscape of 2025 for health plans and discusses why providers are leading in AI adoption. Annie predicts which sectors she'll focus on in 2026, including provider software and AI-driven drug discovery. She expresses caution about employer-centric solutions and mid-level payer challenges. With thoughts on consolidation and the potential for market shifts, she also highlights the need for robust national AI policies.

18 snips
Jan 5, 2026 • 36min
The Antidote to the “Industrial Wellness Complex” | Zeke Emanuel
Ezekiel J. Emanuel, renowned oncologist and health policy expert, joins the discussion to challenge the wellness industrial complex. He highlights that true health doesn't come from expensive trends but rather from six simple habits. Zeke emphasizes the significance of social connections for longevity and critiqued the complexity of healthcare systems. He also shares insights into AI's potential to improve empathy in medicine and outlines his vision for a more equitable healthcare system by 2040, reinforcing the importance of quality over mere longevity.

Dec 29, 2025 • 46min
Former Presidential Candidate Gets Real About America's Future | Andrew Yang 🧢
Andrew Yang, entrepreneur and former presidential candidate, dives into pressing issues facing America today. He shares his vision of 'Medicare for all who want it' while examining the challenges posed by rising healthcare costs. Yang discusses the disruptive impact of AI on jobs, particularly its effects on young men. He elaborates on his Universal Basic Income concept and its potential to address social instability. Additionally, he critiques healthcare lobbying and introduces Noble Mobile, a venture tackling phone addiction among youth.

Dec 22, 2025 • 37min
The Rise of Clinician Innovators | Dr. Reena Pande
Dr. Reena Pande, a physician and healthcare executive, shares her inspiring journey from cardiology to leading clinician executive search at Oxeon. She discusses the importance of self-assessment for clinicians contemplating a leap into startups and emphasizes networking and mentorship as crucial for mitigating risks. Reena introduces the 'indoor cat vs. outdoor cat' model for clinician leaders and highlights the vital role of clinician executives in virtual care. She also argues for evolving medical education to prepare future clinicians for an AI-driven landscape.

7 snips
Dec 15, 2025 • 30min
Soul-Driven Healthcare Investing | General Catalyst CEO Hemant Taneja
In this engaging discussion, Hemant Taneja, CEO of General Catalyst and investor in transformative healthcare solutions, shares insights on shifting the focus from revenue to meaningful impact in healthcare. He critiques profit-only capitalism, arguing it hampers true system change. Hemant also explores his innovative 'health assurance' thesis, the potential of AI to cut costs, and why investing in a hospital was a strategic move for General Catalyst. Tune in to hear how technology can redefine healthcare’s future!

Dec 8, 2025 • 45min
The Haves & Have-Nots Of 2025 | Threshold Ventures Co-founder Emily Melton
Emily Melton, co-founder of Threshold Ventures, shares her insights on healthcare's urgent future. She highlights a stark divide between thriving 'high flyers' and overlooked companies in health tech. Melton discusses the vital role of technology in addressing healthcare's immense cost structure and the impact of policy and private equity on M&A. She emphasizes the importance of founder grit and adaptability in today's venture landscape and encourages innovators to leverage constraints for building value.

8 snips
Dec 1, 2025 • 34min
📣 Digital Health Download: December 2025
Explore the rise of Eli Lilly as the first trillion-dollar healthcare company and the impacts of GLP-1 drug dynamics. Delve into two significant longevity funding rounds, with $298M and $60M raises that highlight celebrity influence in health startups. Discover the ramifications of CVS’s $5.7B write-down and the educational landscape shift as nursing loses its 'professional' status. Finally, unravel a telehealth scandal with federal convictions, sparking questions about ethics in healthcare.

20 snips
Nov 24, 2025 • 35min
Fixing Rural Healthcare Before It Collapses | Homeward Co-founder & CEO Dr. Jennifer Schneider
Dr. Jennifer Schneider, co-founder and CEO of Homeward, shares her journey from a small-town upbringing to revolutionizing rural healthcare. She discusses the staggering mortality rates in rural areas and how Homeward is tackling this by merging technology with personal care. Jenny’s experiences with Type 1 diabetes drive her vision for patient-centered solutions. The conversation also dives into the potential of value-based care in these underserved markets and the innovative hybrid model that combines home visits with virtual follow-ups to enhance access and quality.


