Eric Jorgenson, author and CEO of Scribe Media, discusses the death of the marketing department, changing economics for creators, the impact of Balaji, the future of publishing, embracing collaboration, and the disintermediation of traditional publishing in this entertaining podcast.

Arkady Kulik, founding partner of rpv, discusses how to evaluate deep tech deals, lack of scientist entrepreneurs, self-censorship in science, two types of motivation, neurotech benefits, and more!

Alex Lieberman, Co-founder of Morning Brew, discusses how hiring a Voice Editor contributed to Morning Brew's success, spotting a writing unicorn, following intrinsic motivation, the flaws in the interview process, the concept of arbitrage, stepping out of the CEO role, rewriting internal stories, building a personal media company for executives, and the power to change the world.

Tim Beiko, who runs Ethereum's core protocol meetings, teams up with writer Venkatesh Rao to discuss their 'Summer of Protocols' research program. They explore the importance of protocols, workplace safety, the consequences of ignoring hand hygiene in medicine, evolution of protocols and cultural adaptation, urban protocols, the importance of state and memory in technological systems, and the social side of blockchains.

Will Schoder, a video essayist exploring diverse topics, joins the podcast to discuss the evolving significance of curation, the future of the creator economy, and how to obtain deep happiness. They also explore the influence of short-form content, the concept of compression and uncompression, and the potential of psychedelics for mental health.

Investigative journalist Ben Westhoff discusses the fentanyl drug epidemic, China's role in its manufacturing, and the controversy surrounding Naltrexone as an opioid addiction treatment. He also explores the challenges faced by people in poverty when accessing treatment centers and the connection between the drug crisis and affordable housing. Plus, he highlights the importance of raising awareness, addressing drug addiction, and the need for mentorship and empathy.

AI researcher, Roon, discusses shape rotators vs. wordcels, potential AGI futures, and why Tenet is Christopher Nolan's best movie. They explore meme culture, storytelling, and the broadening task distribution of AI. They also touch on the Kessler Syndrome and AI ethics, emphasizing the importance of embracing abundance and taking risks.

Katherine Dee, a writer and journalist, discusses the role of Twitter in journalism, escaping the nostalgia trap, and healing our attention spans. They also explore the complexities of social class, the influence of social media platforms, and the tendency to romanticize the past. Other topics include attractive women on Twitter, etiquette, literature, and viral food trends.

Entrepreneur and author Derek Sivers returns for Part Two of the conversation. Topics include curiosity, reframing problems, the best choice commitment, and just doing the thing. Derek shares two things he would say to the world as emperor, encouraging people to consider other perspectives and start humbly.

Derek Sivers, entrepreneur and author, talks about his diverse experiences and philanthropy. The podcast explores painting styles, language, and the power of execution. It emphasizes the importance of execution in business ideas and distinguishing beliefs from facts. The power of simplicity in computer programming and the trade-off between simplicity and safety in personal finance are discussed.