
Physionic
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic!
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Latest episodes

Feb 19, 2020 • 33min
Phospholipase on Muscle Growth; Autophagy in Cancer and a Mystery Ally; New Antibiotic
In this episode, we will be diving extensively into a powerful muscle promoting mechanism known as phospholipase. Following that, we dive into a potential treatment for cancer using an unlikely ally. Finally, I discuss research out of McMaster University developing a new style of antibiotic.
Phospholipase (1:18)
https://www.youtube.com/watch?v=EtV3yWw0hz8&t=3s
Cancer & Unlikely Ally (19:20)
Xue Zhang, Tingting Zhang, John N. Davis, Andrea Marzi, Anthony M. Marchese, Michael D. Robek, Anthony N. van den Pol. Mucin-like domain of Ebola virus glycoprotein enhances selective oncolytic actions against brain tumors. Journal of Virology, 2020; DOI: 10.1128/JVI.01967-19
Antibiotic: (25:15)
https://www.sciencedaily.com/releases/2020/02/200212131523.htm

Feb 12, 2020 • 39min
How does your Body fix Mutations?, Heart Rate Variability, Caffeine causes Migraines?
In this podcast, I admittedly nerd out a bit on genetics and how our cells repair our genes when exposed to mutagens (things that cause mutations). However, with good reason, because a new paper has added some clarity to a part of the process and man is it cool! Beyond that, we will go into heart rate variability, as well as if caffeine is associated with migraines? Check it out and share!
Rad DNA Repair, 1:03
Roxanne Oshidari, Richard Huang, Maryam Medghalchi, Elizabeth Y. W. Tse, Nasser Ashgriz, Hyun O. Lee, Haley Wyatt, Karim Mekhail. DNA repair by Rad52 liquid droplets. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-14546-z
Heart Rate Variability, 26:20
Giorgio Quer, Pishoy Gouda, Michael Galarnyk, Eric J. Topol, Steven R. Steinhubl. Inter- and intraindividual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults. PLOS ONE, 2020; 15 (2): e0227709 DOI: 10.1371/journal.pone.0227709
Caffeine on Migraines, 31:28
https://www.sciencedaily.com/releases/2019/08/190808091422.htm
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Feb 5, 2020 • 33min
Thoughts on Coronavirus, New Contraceptive Technology, Marijuana & Birth, and more
In this episode, we'll be discussing four topics:
1:47 - Coronavirus
14:46 - Contraceptive Technology
22:36 - Marijuana & Birth
28:08 - Sleep Deprivation & Hunger
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Jan 29, 2020 • 36min
Spontaneous, life threatening, meat allergies; ageotyping; cellular asthma, and more
In this week's episode, we will be discussing many subjects ranging from sudden meat allergies, how asthma presents itself (cellularly), to different "styles" of aging known as ageotypes, as well as even more! Topics and time stamps listed here:
Meat Allergy (2:37): https://www.jimmunol.org/content/203/4/813
Selective Asthma (10:50): https://www.nature.com/articles/s41590-019-0496-9
Skin Pain Sensation (19:38): https://science.sciencemag.org/content/365/6454/695
Ageotypes (26:10): https://www.nature.com/articles/s41591-019-0719-5
Protein on Health (31:42): https://www.physionic.org/highproteinonhealth

Jan 22, 2020 • 33min
Diet on Male Fertility, Non-HDL Cholesterol on Heart Disease
In this episode, we will go over three articles describing the affect genetics play on cardiovascular disease, as well as sleep's mitigating role. We will also discuss how non-HDL cholesterol affects heart disease risk. Finally, we briefly discuss a study on extreme sugar consumption and its impact on male fertility.
(2:28) Genetics & Sleep: Mengyu Fan, Dianjianyi Sun, Tao Zhou, Yoriko Heianza, Jun Lv, Liming Li, Lu Qi. Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants. European Heart Journal, 2019; DOI: 10.1093/eurheartj/ehz849
(11:32) Non-HDL Cholesterol: Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. The Lancet, 2019; DOI: 10.1016/S0140-6736(19)32519-X
(24:00) Sugar on Fertility: Daniel Nätt, Unn Kugelberg, Eduard Casas, Elizabeth Nedstrand, Stefan Zalavary, Pontus Henriksson, Carola Nijm, Julia Jäderquist, Johanna Sandborg, Eva Flinke, Rashmi Ramesh, Lovisa Örkenby, Filip Appelkvist, Thomas Lingg, Nicola Guzzi, Cristian Bellodi, Marie Löf, Tanya Vavouri, Anita Öst. Human sperm displays rapid responses to diet. PLOS Biology, 2019; 17 (12): e3000559 DOI: 10.1371/journal.pbio.3000559
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Jan 16, 2020 • 51min
5 Laws of Health, Winning the War on Cancer, Creatine on Muscle Hypertrophy
In this episode, we take a deeper look at a recent video I released on YouTube wherein I describe 5 immutable "laws" of health. Then, we will discuss two bits on cancer research - one wonderful and one interesting. Finally, we finish off with a discussion of "does creatine increase muscle mass directly?"
6:18 - 5 Laws of Health
22:12 - War on Cancer
30:00 - Ketones and Breast Cancer
40:47 - Creatine direct affect on Muscle Hypertrophy?
Ketones on Cancer: https://www.physionic.org/overexpressingketonesonbreastcancer
5 Laws of Health: https://www.youtube.com/watch?v=US684eYHLMY&t=1s

Jan 8, 2020 • 1h 8min
Endometriosis: Cause of Pain? Treatments? Diagnosis? Symptoms? and More, Ft. Alyssa Dotson
This week's episode is an intriguing one as it involves an in-depth dive into the condition known as endometriosis. I am joined by Alyssa Dotson, who had endometriosis and spent several years reading up on the condition. We dive into treatment, diagnosis, her story, what endometriosis is, as well as a study that claims to have found the cause of endometriosis pain, as well as much more.
Time Stamps:
What is Endometriosis? (2:02)
What causes Endometriosis? (3:08)
Signs & Symptoms? (6:49)
How long has Endometriosis been around, clinically? (19:37)
Treatments for Endometriosis? (20:58)
Does Endometriosis worsen? (28:35)
When should you see a doctor? (30:11)
Being your own advocate with your doctor? (31:29)
Are there proven tests to diagnose Endometriosis? (33:05)
How prevalent is Endometriosis? (35:05)
When does Endometriosis occur in life? (36:06)
What causes the pain associated with Endometriosis [STUDY] (38:37)
Alyssa's IG: @alyssamckenzie
Nancy's Nook: https://www.facebook.com/groups/NancysNookEndoEd/?fref=nf
Study: https://www.physionic.org/endometriosispain

Dec 27, 2019 • 47min
Dogs for Mental Health, Balancing Blood pH, Sleeplessness on Food Choices
In this episode, you will hear a little bit on how dogs may have an effect in regards to mental health, how the body uses a particular reaction to control blood pH (acidity and alkalinity), how sleep impacts our food choices (or, the lack thereof), and more. Check it out!
3:29 - Dogs
12:09 - Blood pH
27:32 - Sleep & Food Choice
34:49 - Calorie Deficit & Lifespan
Reference: Robert Yolken, Cassie Stallings, Andrea Origoni, Emily Katsafanas, Kevin Sweeney, Amalia Squire, Faith Dickerson. Exposure to household pet cats and dogs in childhood and risk of subsequent diagnosis of schizophrenia or bipolar disorder. PLOS ONE, 2019; 14 (12): e0225320 DOI: 10.1371/journal.pone.0225320

Dec 19, 2019 • 14min
Infrared Sauna for Heart Disease?
In this episode, we dive into how infrared sauna therapy may or may not be beneficial for endothelial function/heart disease.
Study, Notes, & Amendments: https://www.physionic.org/infraredsaunaforheartdisease
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Dec 18, 2019 • 5min
A Benefit of Starting an Exercise Lifestyle Early
In this episode, I discuss why it is imperative to start your exercise life early in this particular regard - your bones.
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