
Physionic
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic!
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Latest episodes

May 7, 2020 • 27min
How do Muscles convert Mechanical Force to Molecular signals? Well, its Confusing.
In this episode, I'll (attempt) walk us through two papers that have tried to answer how our muscles convert mechanical force/stimulus into a molecular signal that produce change. It's definitely not concrete and you will have to bear with me, but we're slowly getting to an answer.
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Apr 29, 2020 • 30min
Hydroxychloroquine & Remdesivir work against CoVID-19? How?
In this episode, we dive into the big two drug players on the front against CoVID-19 - hydroxycloroquine and remdesivir. Do they work? If so, how do they work?
References:
Remdesivir:
https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins
https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056
Hydroxycloroquine:
https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v3
https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2
https://www.nature.com/articles/s41584-020-0372-x
https://www.nature.com/articles/s41421-020-0156-0

Apr 22, 2020 • 30min
How CoVID-19 affects our Organs (other than the Lungs); Why your Mask is Ineffective and how to Fix it.
In this episode, I dive into a bit of less covered information related to coronavirus CoVID-19 related to the variety of organ systems it affects and how it might be exerting it's effect. I also give some quick information on how to effectively improve your mask that you produce for yourself.
Reference:
https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes?fbclid=IwAR1ZjxcdJiFXwSI_FfxhdBscZdT6G6jLc_RPEsnEL99CDe09_r8WE_p9VJc#
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420971/?fbclid=IwAR3Z4zChhXgvZPXk8M0We92wrneMF9h-tSnG8hxJ4fPOj_nCMaYwnXkd09c#__ffn_sectitle

Apr 15, 2020 • 55min
Transhumanism: Uploading our Consciousness for the Future, ft. Neuroscientist Garrett Bunce
Hi everyone, this is a really special episode, because I had the absolute pleasure of having a super smart friend of mine come on the podcast to discuss a topic he's quite passionate about and on which knows a wealth of information. In this podcast, I discuss the topic of "Transhumanism" with Garrett Bunce. Transhumanism is moored in the idea of traveling consciousness beyond our current existence - can we "upload" our consciousness to a machine and continue our existence? If so, what hurdles are in the way and where are we in the process so far? Garrett takes it away - I hope you enjoy!
Garrett's Contact Information:
IG: @garryScary
Twitter: @garryscary
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Apr 8, 2020 • 36min
Coronavirus Q&A; Bad Study on Effectiveness of Masks
In this episode, we'll be continuing our discussion of CoVID-19 coronavirus, as well as jumping into a bit of data in a study discussing the effectiveness of masks.
Study: https://www.nature.com/articles/s41591-020-0843-2/figures/1
Video:
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Mar 25, 2020 • 56min
Responding to the Coronavirus Conspiracy Theorists
In this episode, I spend the entire time discussing the multitude of comments I have (and will) receive on my latest coronavirus video - hopefully you get some information out of it, at least.
Coronavirus Video: https://www.youtube.com/watch?v=j1lcAINElzY
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Mar 18, 2020 • 32min
Everything Coronavirus: How long until you show symptoms? Is a 14 day quarantine enough? How to workout in quarantine?
In this episode, we will dedicate the entire podcast talking about the coronavirus (COVID-19) - how long until you show symptoms of the infection? Is a standard 14 day quarantine efficient? And, if you're stuck at home without workout equipment, how do you still make fitness progress with in resistance training?
Coronavirus video (with images and data): https://youtu.be/aNqL76phkik
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Mar 11, 2020 • 27min
The Athlete's Paradox: The Similarity between Obesity and Athletes; Muscle & Strength, and More
In this episode, I cover the microbiome, as well as muscle and its relation and impact on strength gain, as well as the ever confusing "Athlete's Paradox".
Microbiome: 1:48
Muscle & Strength: 10:07
Athlete's Paradox: 16:40

Mar 4, 2020 • 32min
Longer Pregnancy & Genetics Changes; BioInk Printing Skin; Nuances in reading Studies; Coronavirus is Local...
In this episode, I cover a broad range of topics from pregnancy length and its affect on children's genetics, as well as a new technology that makes printing skin a new therapy possible. Finally, I answer a question/concern a commenter had over why scientists waste their time with "obvious questions".
1:48 - Pregnancy
Merid, S.K., Novoloaca, A., Sharp, G.C. et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med 12, 25 (2020). https://doi.org/10.1186/s13073-020-0716-9
10:37 - Printing Skin
Richard Y Cheng, Gertraud Eylert, Jean-Michel Gariepy, Sijin He, Hasan Ahmad, Yizhou Gao, Stefania Priore, Navid Hakimi, Marc G Jeschke, Axel Günther. Handheld instrument for wound-conformal delivery of skin precursor sheets improves healing in full-thickness burns. Biofabrication, 2020; 12 (2): 025002 DOI: 10.1088/1758-5090/ab6413
17:03 - Science Wasting Time

Feb 26, 2020 • 34min
High Protein Diets implicated in Artery Plaques; Air Pollution & Heart Attacks; Ranting on Selective Bias
In this episode, I discuss a paper looking at high protein diets and their impact on atherosclerosis, as well as air pollution and its correlation with heart attacks, and the final half is me ranting on how selective people get to fit their biases.
Poor Sleep & Obesity (2:09)
https://www.sciencedaily.com/releases/2020/02/200217085214.htm
High Protein (7:34)
https://www.sciencedaily.com/releases/2020/01/200123152614.htm
Air Pollution (12:58)
https://www.sciencedaily.com/releases/2020/02/200214134717.htm
Selective Bias Rant (16:15)