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Physionic

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Jul 22, 2020 • 36min

Making Sense of the Microbiome, ft. Bern Monari

In this episode, I had the pleasure of having a friend and microbiome researcher Bern Monari on to educate us on the microbiome and the research therein. I hope this podcast ends up interesting, because I certainly found it to be, and Bern adds quite a bit to my knowledge of the matter. Enjoy! Bern's LinkedIn (to ask questions): https://www.linkedin.com/in/bernadinemonari/ YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i Podcast: http://bit.ly/2PThKz0 Email Opt-In: http://bit.ly/2AXIzK6 Facebook Page (Poll Question): http://bit.ly/2PlIOaB Patreon: http://bit.ly/2OBBna0   Bern's References: 1. Marchesi JR, Ravel J. The vocabulary of microbiome research: a proposal. Microbiome. 2015;3:31. 2. NIH Human Microbiome Project defines normal bacterial makeup of the body [press release]. nih.gov: NIH, 2015-08-31 2015. 3. Ochman AHM, Steffen F, Michael LW, Anne EP, Beatrice HH, Howard. Social behavior shapes the chimpanzee pan-microbiome. Science Advances. 2016;2(1). 4. Engel P, Kwong WK, McFrederick Q, et al. The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions. mBio. 2016;7(2):e02164-02115. 5. Rudman SM, Greenblum S, Hughes RC, et al. Microbiome composition shapes rapid genomic adaptation of Drosophila melanogaster. Proceedings of the National Academy of Sciences. 2019;116(40):20025-20032. 6. Edwards VL, Smith SB, McComb EJ, et al. The Cervicovaginal Microbiota-Host Interaction Modulates <span class="named-content genus-species" id="named-content-1">Chlamydia trachomatis</span> Infection. mBio. 2019;10(4):e01548-01519. 7. Jobira B, Frank DN, Pyle L, et al. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. The Journal of Clinical Endocrinology & Metabolism. 2020;105(6). 8. Luu M, Monning H, Visekruna A. Exploring the Molecular Mechanisms Underlying the Protective Effects of Microbial SCFAs on Intestinal Tolerance and Food Allergy. Frontiers in Immunology. 2020;11(1225). 9. Allegretti J. Stool transplants are now standard of care for recurrent C. difficile infections - Harvard Health Blog. health.harvard.edu. https://www.health.harvard.edu/blog/stool-transplants-are-now-standard-of-care-for-recurrent-c-difficile-infections-2019050916576. Published 2019. Updated 2019-05-09. Accessed2020. 10. Types of Infections After Stem Cell or Organ Transplants. https://nyulangone.org/conditions/infections-after-stem-cell-or-organ-transplants/types. Published 2020. Accessed 07/16/2020, 2020. 11. Cdc. Reports of Selected E. coli Outbreak Investigations | E. coli | CDC. 2020. https://www.cdc.gov/ecoli/outbreaks.html. Accessed 2020-02-26T02:39:54Z. 12. van de Wijgert JHHM, Verwijs MC, Agaba SK, et al. Intermittent Lactobacilli-containing Vaginal Probiotic or Metronidazole Use to Prevent Bacterial Vaginosis Recurrence: A Pilot Study Incorporating Microscopy and Sequencing. Scientific Reports. 2020;10(1):1-15. 13. Yong E. You're Probably Not Mostly Microbes. The Atlantic. 2016-01-08, 2016.
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Jul 15, 2020 • 36min

Behind the Scenes of a CoVID-19 Vaccine, Side Effects, & Science Explained, ft. David Rach

In this episode, I had the pleasure of having a fellow researcher and class mate David Rach on the podcast to discuss his experience as a participant in a CoVID-19 vaccine trial. However, not only that, he is getting his PhD in Microbiology and Immunology, so he was able to discuss some of the science behind vaccine development, as well as the preliminary results of the trial he was in. David's Info Twitter: @DavidRach2 Facebook Post on the Topic: https://tinyurl.com/yazocyla Vaccine Trial Data: https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1.full.pdf?fbclid=IwAR3guvvo_TdhDAh1tDZwTUH5rRH-p-I7sanyfoM9Dp3-8wK-cydchyNrmEU More info: coronaviruspreventionnetwork.org
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Jul 8, 2020 • 19min

Fiber, Stomach Bloating, and Potential Solutions

In this episode, we'll be taking a look at some information on fiber, but more poignantly focused on stomach bloating and how it relates to fiber, as well as some things to consider to lower bloating from the lack or incorrect fiber intake. Fiber & Gas Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774297/ YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
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Jul 1, 2020 • 32min

Skin Care and Ingredients that Work

In this episode, I go on a monologue wherein I discuss the various ways skin can be damaged and become unhealthy before diving into a few habits and ingredients that have been known to aid in replenishing the health and youth of our skin. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
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Jun 24, 2020 • 23min

Woman Cured of Genetic Disease by Genetic Engineering - The Power of CRISPR

In this episode, I decided to dedicate some time to discussing the brand new reports that a woman suffering from sickle cell anemia has been effectively cured of the disease that would have continued to ruin her life moving forward. The cure wasn't a drug, but the first time use of genetic engineering to cure the disease. Pretty brilliant work on all involved. Article: https://www.npr.org/sections/health-shots/2020/06/23/877543610/a-year-in-1st-patient-to-get-gene-editing-for-sickle-cell-disease-is-thriving YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
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Jun 17, 2020 • 31min

Balancing Intensity for Effective Home Workouts; How Cancer evades Chemotherapy

In this episode, I discuss two topics. First, we go into how to change the intensity variable when building an effective at home workout program for muscle growth, muscle maintenance, and muscle tone. Secondly, we dive into a bit of cancer and how cancer can "hide" or protect itself against chemotherapies - how does it return? 2:48: Workout at Home 21:35: Cancer & Chemotherapy
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Jun 10, 2020 • 35min

United States Medicine in the 1800s; Zoonotic Origin of Viruses

Hey everyone, in this episode, I'll be going into a bit of history on how the United States handled their medical practices in the 1800s by comparison to Europe. I talk about the impact Johns Hopkins University had on the entire medical field in the United States, and then I discuss a bit on zoonotic viruses (viruses that jump from animals to humans). Medical History: 1:36 Zoonotic Virus: 23:04 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
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Jun 3, 2020 • 19min

Spices on Food that fight Cardiovascular Disease & Inflammation; Pain Perception in the Brain

In this episode, we'll be going into a bit of research on pain perception mediated by a particular area of the brain that wasn't pegged as one related to pain. Beyond that, do spices on food reduce inflammation and cardiovascular disease? If so, which ones? Pain (2:01): Thuy Hua, Bin Chen, Dongye Lu, Katsuyasu Sakurai, Shengli Zhao, Bao-Xia Han, Jiwoo Kim, Luping Yin, Yong Chen, Jinghao Lu, Fan Wang. General anesthetics activate a potent central pain-suppression circuit in the amygdala. Nature Neuroscience, 2020; DOI: 10.1038/s41593-020-0632-8 Spices (10:17): Connie J Rogers, Penny M Kris-Etherton, Kristina S Petersen, Ester S Oh. Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial. The Journal of Nutrition, 2020; DOI: 10.1093/jn/nxaa063
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May 20, 2020 • 39min

How much does being Overweight INCREASE Risk of Severe CoVID-19 symptoms? Why are Fit people Dying?

In this episode, I go into two reviews discussing some of the data surrounding being overweight or obese and how much it increases risk of serious issues when dealing with CoVID-19. Also, why are fit people struggling with this infection, and what are some of the presented reasons/mechanisms? Review 1: https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22842 Review 2: https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047659 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
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May 13, 2020 • 54min

Understanding Microbes and How Fungi impact Us, ft. Alex Soare

In this episode, I had the absolute pleasure of having yet another smart scientist on the podcast. Alex Soare is on to discuss a bit of basic immunology and microbiology for the first half of the podcast, then we dive into fungi and her expertise on mucormycosis. I hope this proves as informative as I found it (considering I knew nothing about fungi). Alex's Twitter: https://twitter.com/AlexandraYSoare National AWIS Link: https://www.awis.org/ Baltimore AWIS:  https://twitter.com/AWISBalt https://www.instagram.com/awisbaltimore/ https://www.facebook.com/AWISBaltimore/ http://www.awisbaltimore.org/home Time Stamps: 2:41 - Alex Education 4:34 - What is a microbe? 7:13 - Is a microbe a pathogen? 9:05 - Pathogen in a Host always causing disease? 15:53 - How do we fight disease? 21:53 - What is a fungus? 27:09 - Increase in fungal infections in the news - why? 31:57 - Do fungi mutate? 32:59 - What is Mucormycosis? 37:45 - How does it affect the body? 40:45 - Cures for Mucormycosis? 43:25 - Fungal infections are rare although they’re everywhere, why? 46:11 - Where is fungal research headed? 48:50- Is there an area in fungal research you’re excited? 50:32 - AWIS background YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

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