Manifold

Steve Hsu, a theoretical physicist and tech entrepreneur, shares his insights on the geopolitical landscape for 2026. He discusses the complexities of US-China economic tensions and the limitations of tariffs. Hsu analyzes Trump's strategic shifts and the implications of U.S. dominance reduction in the Western Pacific. He also explores the dynamics of the Middle East and the challenges facing Ukraine. The conversation highlights China's technological advancements, Venezuela's political turmoil, and the reliability of international law in a changing world.

Explore groundbreaking advancements in polygenic embryo screening that could reshape healthcare and attitudes toward intelligence traits. The discussion dives into how elite demand and shifting perceptions are driving innovation in IVF technologies. Transitioning to AI, listeners learn about significant progress in research capabilities, including breakthroughs in physics and enhanced model performance through innovative methods. Predictions for 2026 suggest an exciting future for both genomics and artificial intelligence.

Dive into the fascinating intersection of AI and theoretical physics! Discover how cutting-edge AI models, like GPT-5, are reshaping research in quantum field theory. Steve discusses AI's dual nature as a 'brilliant but unreliable genius,' highlighting its successes and missteps. Hear about an AI-generated integrability condition that led to a publishable paper. Explore the dynamic of human-AI collaboration and the future of science as researchers leverage AI to push theoretical boundaries.

Murtaza Hussain, an investigative journalist at DropSite News, dives deep into the connections between Jeffrey Epstein, Israeli intelligence, and elite power dynamics. He reveals Epstein's extensive ties with U.S. and Israeli intelligence agencies, portraying him as a high-level fixer. The discussion uncovers Epstein's role in back-channel diplomacy, illuminates his segmented email accounts, and examines how he operated as an Israeli asset. Hussain also highlights the media's suppression of these crucial narratives and explores the implications for national security.

Jian Lian, a policy analyst with deep expertise in China's political economy, discusses the nation's bold industrial policies and technological innovations. He contrasts China's industrial maximalism with Western liberal economic views and dives into the impact of US sanctions on Huawei's rise. Jian also highlights China's aggressive push in the semiconductor sector and the growth of domestic supply chains. With insights on 'hard tech' investments and the Made in China 2025 goals, he outlines China's ongoing strategies for global economic engagement and innovation.

Scott Horton, Director of the Libertarian Institute and author of "Provoked," delves into the intricate ties between the Russiagate investigation and U.S. foreign policy, particularly regarding Ukraine. He explores the orchestrated efforts against Trump, including the dubious Steele dossier and the CIA-FBI collaboration. Horton argues that U.S. policy provoked tensions with Russia and critiques missed diplomatic opportunities in Ukraine. His insights raise questions about political accountability and the impact of media narratives.

Lin Yang, a computer science professor at UCLA with dual PhDs in physics and computer science, discusses his groundbreaking work with AI in solving International Math Olympiad problems. He explains the innovative verifier-refiner pipeline that allows models like ChatGPT to reach gold medal levels. The conversation dives into industry applications, the efficiency of token budgeting, and the future of AI in scientific research and legal analysis. Yang also shares insights into the limitations of current models and the potential path toward AGI.

Zixuan Li, Director of Product and genAI Strategy at Z.ai, shares insights from Beijing's AI startup scene. He dives into Z.ai's evolution and open-source models, contrasting them with Western AI developments. Discussions reveal the competitive landscape, talent market dynamics, and government support in China. Li highlights the pragmatic view on AGI, emphasizing practical applications rather than hype. He also touches on the challenges of commercialization and the vibrant community pushing innovation, showcasing Beijing's energetic tech culture.

Steve Hsu, a theoretical physicist and founder of multiple startups, dives into geopolitical changes reshaping the world. He discusses China's military advancements, including scramjet hypersonics, and the significance of the recent SCO summit with leaders like Xi and Modi. Hsu explores the potential for a Sino-Indian rapprochement despite historical tensions and critiques U.S. strategies that may have pushed India closer to China. The conversation also touches on shifting sentiments toward Israel among Americans and the implications of a multipolar world.

Kyle Chan, a Postdoctoral Research Associate at Princeton, dives into the fierce competition between the U.S. and China. He explains how China has overtaken industries like electric vehicles and solar tech, originally dominated by Western powers. Chan discusses the contrasting railway developments in China and India, spotlighting efficiency versus bureaucracy. He addresses the implications of industrial policy on global perspectives and highlights the need for the U.S. to innovate and collaborate to ensure technological relevance amidst rising Chinese advancements.