
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you’ve come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.
Latest episodes

107 snips
Dec 9, 2024 • 1h 9min
298 | Jeff Lichtman on the Wiring Diagram of the Brain
Join neuroscientist Jeff Lichtman, a leading figure in brain mapping from Harvard, as he reveals the wonders of the human brain's wiring. Discover the remarkable Brainbow technique that illuminates neuron connections. Lichtman discusses the challenges of mapping the human connectome and how it compares to simpler organisms. He touches on the self-organizing nature of neural networks and the ethical considerations of brain research. Dive into his insights on consciousness and the potential for neuroscience breakthroughs in understanding human behavior.

63 snips
Dec 2, 2024 • 3h 56min
AMA | December 2024
In a lively AMA format, listeners explore the rapidly shifting landscape of information during the 2024 elections. Topics include innovative ideas for improving democracy and accountability in legislation. Marvel at the complexities of black holes, event horizons, and the nuances of dark energy in space-time dynamics. The host shares personal anecdotes about finding style and comfort in public speaking, tying scientific discourse to everyday life. This conversation weaves together thought-provoking reflections on truth, ethics, and the pursuit of knowledge.

17 snips
Nov 25, 2024 • 1h 15min
297 | Emily Wilson on Homer, Poetry, and Translation
Emily Wilson, a Professor of Classical Studies at the University of Pennsylvania, is celebrated for her translations of Homer’s epics. In this conversation, she explores the complexities and nuances of translating The Iliad and The Odyssey. Topics include the evolution of these tales from oral to written form, the impact of translation on identity, and the emotional depth achieved through storytelling. Wilson also discusses the significance of the divine in human experience within the texts, and the artistic challenges translators face in capturing their essence.

22 snips
Nov 18, 2024 • 1h 16min
296 | Brandon Ogbunu on Fitness Seascapes and the Course of Evolution
Brandon Ogbunu, an Assistant Professor at Yale University specializing in Ecology and Evolutionary Biology, dives into the complexities of evolutionary fitness. He discusses fitness landscapes and how they help us understand adaptation in changing environments. The conversation highlights the role of mathematical tools in evolution, the unpredictability of gene mutations, and the impact of modern technologies like CRISPR. Ogbunu also connects evolutionary insights to medical challenges, particularly in understanding drug resistance, showcasing the need for a multidisciplinary approach.

138 snips
Nov 11, 2024 • 1h 35min
295 | Solo: Emergence and Layers of Reality
Delve into the fascinating world of emergence, where complex systems arise from simple interactions. Discover how understanding higher-level properties helps us make sense of reality, even without a complete view of the microscopic. Explore the political implications of emergence and consciousness while pondering everyday phenomena like crumpled paper to highlight unpredictability. Learn about the distinctions between strong and weak emergence and their relevance across science, philosophy, and human behavior, all presented with engaging examples and thoughtful insights.

121 snips
Nov 4, 2024 • 3h 50min
AMA | November 2024
This conversation dives into the implications of the upcoming U.S. presidential election, focusing on Biden's campaign and the dangers to democracy posed by low-information voters. It also explores the complexities of composing hiring practices to align organization needs with candidate suitability. Highlights include an examination of quantum mechanics, ethical dilemmas in advanced warfare, and the philosophical debates surrounding time and entropy. Furthermore, it touches on the juxtaposition of space exploration and urgent environmental issues.

57 snips
Oct 28, 2024 • 1h 12min
294 | Addy Pross on Dynamics, Stability, and Life
Addy Pross, Professor Emeritus of Chemistry at Ben-Gurion University and author of "What Is Life? How Chemistry Becomes Biology," discusses dynamic kinetic stability as a key to understanding life's origins. He challenges traditional physics notions, emphasizing the importance of energy and adaptability in biological systems. Through fascinating analogies, he illustrates how living organisms maintain stability despite constant change. Pross also explores the intricate relationship between metabolism, replication, and the evolution of consciousness, prompting listeners to rethink life's complexity.

61 snips
Oct 21, 2024 • 1h 11min
293 | Doyne Farmer on Chaos, Crashes, and Economic Complexity
Doyne Farmer, Director of the Complexity Economics program at Oxford, dives into the chaotic nature of economies and the inadequacies of traditional economic models. He highlights how chaos theory can reshape our understanding of financial systems and promote more accurate predictions. Farmer critiques the reliance on equilibrium, advocating for models that embrace dynamic interactions and real-world complexities. He also draws fascinating parallels between economic systems and ecological dynamics, exploring how innovation intertwines with complexity in markets.

24 snips
Oct 14, 2024 • 1h 11min
292 | Jonathan Birch on Animal Sentience
Join Jonathan Birch, a Professor at the LSE and author of "The Edge of Sentience," as he dives into the intriguing world of animal sentience. He discusses the critical differences between consciousness and sentience, shedding light on how various creatures experience emotions. Birch challenges traditional views on animal welfare, addressing the ethics of practices like boiling crustaceans alive. With insights into anticipatory reasoning in animals and recent scientific declarations on sentience, this conversation highlights our ethical responsibilities towards non-human beings.

8 snips
Oct 7, 2024 • 4h 30min
AMA | October 2024
Dive into a fascinating exploration of balancing teaching with engaging AMAs during a bustling semester. Discover the challenges of transitioning careers from songwriting to physics, and the philosophical critiques around the quest for unifying theories in science. Unpack the intricate relationship between entropy, consciousness, and quantum uncertainty. Examine the complexities of democracy while advocating for reform in the electoral system. Finally, reflect on AI's impact on arts and creativity, along with the ethical dilemmas it raises.
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