Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

302 | Chris Kempes on the Biophysics of Evolution

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Jan 20, 2025
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ANECDOTE

Centimeter-Long Bacteria

  • The centimeter-long bacterium Thiomargarita magnifica challenges assumptions about bacterial size limits.
  • It achieves its length by growing as filaments, not as a single large blob.
INSIGHT

Physical Constraints in Biology

  • Biological organisms are embedded in the physical world and obey the laws of physics.
  • This places constraints on their architectures, morphologies, and sizes.
INSIGHT

Dominant Constraints and Convergence

  • Dominant physical constraints create unavoidable valleys in the fitness landscape.
  • These constraints strongly influence trait optimization, leading to convergent evolution.
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