
Two Onc Docs
This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*
Latest episodes

Sep 9, 2024 • 16min
Heme & Onc Fellow Board Review Tips 2024
Dive into expert board review tips that tackle high-yield topics and effective study strategies! Discover crucial updates in breast cancer treatment protocols, including the significance of NCCN guidelines and genetic assays. Master hemoglobin electrophoresis with handy study techniques and resources. Get insights into key hematology subjects, focusing on disorders like Diamond Blackfan anemia and von Willebrand's disease, while also picking up essential self-care tips for a successful preparation.

Aug 27, 2024 • 28min
Palliative Care x Dr. Janet Abrahm Part 1
Dr. Janet Abrahm, a national leader in palliative care and a Harvard Medical School professor, shares invaluable insights on this crucial field. She discusses how to clearly explain palliative care to patients, emphasizing the importance of early supportive care in enhancing quality of life. The conversation delves into pain management strategies, including non-pharmacologic approaches and the role of pharmacists. Abrahm also highlights recent innovations such as intrathecal pumps for pain relief and the use of psychedelics for emotional support.

Aug 19, 2024 • 16min
Hemophilia 2024 UPDATE
This week, explore the intricacies of hemophilia A and B, including their causes linked to clotting factors. Discover groundbreaking advancements in treatment, with a focus on recent gene therapies that are changing patient management strategies. Learn about the challenges of inhibitors and their implications in surgical contexts. Delve into diagnostic procedures and gain insight into tailored treatment options for acquired hemophilia, enhancing your understanding of this complex condition.

Aug 12, 2024 • 10min
ASCO 2024 Plenary: NADINA Trial Neoadjuvant Ipi/Nivo vs Adjuvant Nivo for Resectable Stage III Melanoma
This week’s episode will be discussing updates from ASCO 2024 next with the practice changing NADINA trial presented on the Sunday of ASCO by Dr. Christian Blank during the plenary sessions: A multicenter, randomized, phase 3 trial comparing the efficacy of neoadjuvant ipilimumab plus nivolumab with standard adjuvant nivolumab in macroscopic resectable stage III melanoma. We discuss the staging and prior standard of treatment for locally advanced melanoma, key findings from NADINA, and how these data may impact clinical practice.

Aug 5, 2024 • 15min
Oncology for the IM Board Tips 2024
Dive into vital cancer screening guidelines for internal medicine board exams! Learn about essential prevention strategies through real-life case studies. Discover the significance of recognizing oncological emergencies like neutropenic fever. Explore management techniques for various cancers, including genetic testing and tailored treatments. Plus, gain insights on survivorship challenges faced by cancer survivors and effective study strategies for exam prep.

Jul 29, 2024 • 17min
Hematology for the IM Board Tips 2024
Get ready to ace your hematology questions! Explore essential insights on disorders like aplastic anemia and the intricacies of multiple myeloma diagnosis and management. Delve into myelodysplastic syndrome with a case study that highlights crucial testing. Learn about vitamin B12 deficiency and management strategies for acute promyelocytic leukemia. Finally, unpack bleeding disorders and the critical aspects of transfusion reactions, all with practical tips for your upcoming boards!

Jul 22, 2024 • 13min
Infusion Reactions
This podcast covers infusion reactions in hematology and oncology, including symptoms, treatments, and common drugs causing reactions. They discuss hypersensitivity types, management strategies, and specific drugs like taxanes, platinums, and monoclonal antibodies. The episode provides insights on monitoring, consulting specialists, and guidelines for re-challenging patients.

13 snips
Jul 15, 2024 • 12min
Oncologic Emergencies
This podcast delves into high-yield topics on oncologic emergencies for new fellows and residents, covering brain metastases, hypercalcemia, cord compression, and SVC syndrome. They discuss management strategies like steroids, fluids, bisphosphonates, and RANK L inhibitors, emphasizing the importance of timely interventions for optimal patient care.

Jul 8, 2024 • 12min
ASCO 2024 Plenary: ADRIATIC Trial in Limited Stage Small Cell Lung Cancer
Dr. Spigel presents the ADRIATIC trial at ASCO 2024 focusing on Durvalumab in LS-SCLC. Topics include staging imaging, treatment approaches, trial results with improved outcomes, and future trials in small cell lung cancer space.

Jul 1, 2024 • 28min
Tips for New Doctors (& A Few For New Attendings)
Dr Shikha Jain, founder of Women in Medicine & GI oncologist, shares tips for new doctors & attendings. Topics include teamwork in hospitals, importance of self-care, delivering bad news, continuous learning in medicine, essential tips for new doctors & attendings, and guidance for those in oncology.