Two Onc Docs

Testicular Cancer 2025 UPDATE Part 1 (Seminoma)

Apr 14, 2025
Dive into the world of seminoma, a form of testicular cancer, and discover crucial management strategies and risk factors. Learn about the importance of early symptom recognition, especially in young patients. Explore the diagnosing process with ultrasounds and the significance of tumor markers in monitoring. Unpack various chemotherapy regimens and their tailored approaches based on disease staging. Finally, navigate the complex treatment protocols, focusing on the distinct management of seminoma versus non-seminoma.
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ADVICE

Urgent Workup for Testicular Cancer

  • Always urgently work up suspected testicular cancer with ultrasound and prompt inguinal orchiectomy.
  • Offer sperm banking, do CT scans, check tumor markers, and avoid biopsy of the testis.
INSIGHT

Varied Presentations of Testicular Cancer

  • Testicular cancer can present with painful masses and symptoms of metastases such as back pain and shortness of breath.
  • Unprovoked DVT in young patients should raise suspicion for testicular cancer.
ADVICE

Key Tumor Markers in Testicular Cancer

  • Check AFP, HCG, and LDH tumor markers after orchiectomy for accurate prognosis.
  • Remember seminoma does not produce AFP and tumor markers guide staging and risk.
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