Two Onc Docs
Stem Cell Transplant (SCT) Part 1 x Dr. Jeff Auletta 2025 UPDATE
Apr 28, 2025
Joining the discussion is Dr. Jeff Auletta, a leading voice in blood and marrow transplantation. He shares insights on hematopoietic stem cell transplants, clarifying the various types and the donor matching process. The conversation dives into the risks and benefits of autologous versus allogeneic transplants, highlighting critical disparities in donor availability across ethnic groups. Dr. Auletta also emphasizes the need for systemic changes to address socio-economic barriers and ensure equitable access to transplant services for all communities.
26:50
Episode guests
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- Stem cell transplants can either be autologous or allogeneic, each with distinct risks and benefits, especially regarding immune response and treatment efficacy.
- Efforts to address socioeconomic and systemic barriers are crucial in ensuring equitable access to stem cell transplants for diverse patient populations.
Deep dives
Understanding Stem Cell Transplants
Stem cell transplants are classified into autologous and allogeneic types, involving the provision of stem cells from the patient or a donor, respectively. The process begins with a conditioning regimen, which may include chemotherapy or radiation, followed by the infusion of hematopoietic stem cells. Different methods for collecting stem cells are highlighted, such as bone marrow aspiration or mobilizing stem cells into the bloodstream using cytokines. Additionally, umbilical cord blood serves as a valuable source of stem cells after a baby is delivered.
