Two Onc Docs

This podcast focuses on diffuse large B-cell lymphoma (DLBCL), covering topics such as diagnostic classification, subtypes and molecular markers, necessary tests and evaluations, staging and treatment options, and different treatment regimens for refractory DLBCL. It emphasizes the importance of excisional lymph node biopsy for accurate diagnosis, highlights prognostic factors and high-risk patient considerations, and discusses the use of R-CHOP chemotherapy, radiation, and CAR T therapy. The recommended follow-up protocol for cured patients is also covered.

Exploring the evolving treatment options for metastatic non-small cell lung cancer, including traditional chemotherapy, immunotherapy, and targeted agents. Discussing the significance of targeted medications like EGFR, ALK, and ROS1 inhibitors. Emphasizing the importance of genetic mutation-based sequencing and tailored drug regimens based on PDL1 status.

This podcast delves into the complexities of localized non-small cell lung cancer, covering staging criteria, treatment options, including surgery, chemo, radiation, and immunotherapy. The discussion also highlights the impact of the PACIFIC trial on treatment standards and explores emerging therapies like egf targeting and immunotherapy.

Important details on risk factors, diagnosis, staging, and treatment options for uterine cancer, including less common subtypes. Risk factors include obesity and hormone replacement therapy. Treatment options include surgery, hormone therapy, radiation, and chemotherapy. Uterine sarcomas have different treatment regimens, with the addition of trastuzumab for HER2 positive tumors.

Delve into the fascinating world of hemophilia with insights into the key differences between hemophilia A and B, including their genetic factors. Learn about diagnostic methods, severity classifications, and the importance of family history. Discover effective treatment strategies, focusing on prophylactic factor replacement therapy and its protocols. Explore the challenges posed by inhibitors in treatment and the autoimmune origins of acquired factor deficiencies, particularly in the elderly. Get informed on managing bleeding events and enhancing patient care.

This podcast discusses the risk factors, diagnosis, staging, and treatments for ovarian cancer. It highlights the importance of early detection, germline mutation testing, and the use of carbotaxil as a preferred chemotherapy drug. The podcast also explores treatment options for recurrent disease and different histological types of ovarian cancer.

This week’s episode will be focusing on Hodgkin's Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into all the important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.

This podcast episode focuses on testicular cancer, covering important details on staging, risk categories, and treatment options for both seminoma and non-seminoma. It also discusses the significance of tumor markers, symptoms, workup, and the different stages of testicular cancer. Treatment options include surveillance, surgery, radiation, and chemotherapy regimens. The episode emphasizes the importance of awareness for growing teratoma syndrome and potential toxicities associated with chemotherapy.

This podcast provides high yield concepts and facts for the oncology portion of the IM Boards. Topics covered include cancer screening recommendations, prevention strategies, treatment options for breast and colon cancer, mismatch repair enzymes and immunotherapy for MSI high cases, and the long-term effects of chemotherapy.

The podcast discusses important topics for the ABIM internal medicine exam, focusing on hematology. It explores various disorders related to erythrocytes, leukocytes, platelets, coagulation, transfusion medicine, and heme malignancies. Specific cases are discussed, including evaluation of a fatigued patient with a history of breast cancer, hematological disorders such as APL and TTP, chronic myeloid leukemia and G6PD deficiency. Additionally, vignettes on acquired factor eight inhibitor and post-transfusion purpura are explored, along with insights on appropriate treatment options.