
Two Onc Docs
This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*
Latest episodes

Dec 5, 2022 • 14min
Neuroendocrine Tumors (NET)
Exploring neuroendocrine tumors, their diagnosis, signs, symptoms, and associated syndromes. Discussion on grading system, treatment approaches like surgery and somatostatin analogs. Focus on poorly differentiated grade three tumors with emphasis on chemotherapy, radiation, and specialized treatments.

Nov 14, 2022 • 19min
Board Review Tidbits
This podcast covers tips for the hematology & oncology board exams, including NSCLC treatments and adjuvant chemotherapy. It discusses treatment strategies for breast cancer, bone metastases, and specialized therapies. They also review hemoglobinopathies, Von Willebrand disease, and bone marrow failure disorders. Additionally, the importance of supportive care and wellness during exam preparation is emphasized.

Nov 14, 2022 • 16min
Von Willebrand Disease
Explore the fascinating world of Von Willebrand Disease, a complex bleeding disorder affecting platelet function. Learn about its various types, including memorable mnemonics for distinguishing them. Discover the critical role of von Willebrand factor in blood clotting and how genetics influence diagnosis. Delve into treatment options, from using Desmopressin for milder cases to comprehensive therapies for more severe conditions. Plus, uncover the details of acquired Von Willebrand Disease and its links to autoimmune issues!

Nov 7, 2022 • 13min
Cervical Cancer
This podcast covers important topics on cervical cancer for health care providers, including prevention, risk factors, diagnosis, and treatment. It discusses reducing HPV rates, diagnostic methods, staging criteria, treatment options like hysterectomy and chemotherapy, and advancements in treatment strategies for metastatic or recurrent cervical cancer

Oct 31, 2022 • 11min
Porphyria
Dive into the fascinating world of porphyrias, where medical conditions sparked vampire myths! Discover the symptoms of these metabolic disorders, from photosensitivity to neurological issues. Learn about the critical diagnostic methods for acute porphyrias, including urine tests for porphyrin precursors. Explore porphyria cutanea tarda and its links to iron overload and hepatitis C. With insights on treatment strategies, this discussion equips listeners with essential knowledge for understanding and managing these intriguing conditions.

Oct 24, 2022 • 15min
Chronic Myelogenous Leukemia
This week’s episode will be focusing on Chronic Myeloid Leukemia or CML for health care providers. We will go over all the important details on the genetics of CML, diagnosis and treatment algorithms.

Oct 17, 2022 • 11min
Metastatic Breast Cancer
Explore systemic therapy guidelines for metastatic breast cancer, CDK4-6 inhibitors toxicities, second-line treatments, HER2 positive treatment options, triple negative strategies, and emerging research in the field.

Oct 10, 2022 • 16min
Localized Breast Cancer
Dive into treatment options for localized breast cancer, from radiation to systemic therapies. Explore criteria for radiation post-mastectomy and personalized systemic therapy choices. Learn about chemotherapy regimens based on receptor status and side effects of treatments. Discover tailored treatment strategies based on tumor features, receptor status, and patient preferences, including neoadjuvant chemotherapy for inflammatory breast cancer.

Oct 3, 2022 • 16min
Breast Cancer Screening, Prevention & Intro
Breast Cancer Awareness Month is here! Learn about genetic and non-genetic risk factors for breast cancer, the importance of breast screenings, differences between DCIS and LCIS, treatment options like mastectomy and lumpectomy, side effects of hormone therapy, and surgical options for invasive breast cancer.

Sep 26, 2022 • 11min
Immune Thrombocytopenia
Dive into the world of Immune Thrombocytopenia (ITP) as the hosts explore its causes and idiopathic cases. Uncover the prevalence of this acquired condition and the importance of accurate diagnosis with low platelet counts. Learn about comprehensive management strategies including conservative treatments for kids and intensive options for adults. Key insights on first-line therapies like steroids and IVIG are also discussed, alongside the significance of timely management during bleeding episodes.