Two Onc Docs

This week’s episode will be focusing on alpha thalassemia. We will go over details on the pathophysiology, symptoms, diagnosis and treatment of alpha thalassemia variants.

Learn about the staging and treatment options for both locoregional and advanced Hepatocellular Carcinoma. Discussions include the Child-Pugh score importance, screening serotic patients with ultrasound, key treatments for early-stage HCC, and advancements in systemic therapies for advanced HCC.

Exploring the role of HPV in head and neck cancers, the importance of knowing the anatomy for diagnosis and treatment, and various treatment approaches including chemotherapy regimens, radiation toxicities, and adjuvant therapy options.

Explore the intricacies of beta thalassemia, from its genetic origins to the differing impacts of its minor, intermedia, and major forms. Discover how hemoglobin composition plays a crucial role in diagnosis and treatment. Learn about the critical complications associated with severe cases and the importance of transfusions. The discussion even touches on the challenges of iron overload and examines rare variants of the condition, offering a comprehensive look at this fascinating topic.

Exploring diagnosis, treatment, and prognostic factors of Acute Lymphoblastic Leukemia, including cytogenetics, molecular markers, targeted therapies, and toxicities. Emphasis on differentiating between B-cell & T-cell types, advanced treatment options like CAR-T therapies, and key takeaways for effective management.

Explore the diagnosis, mutations, and treatment options for gastrointestinal stromal tumors (GIST) in this episode. Learn about the effectiveness of tyrosine kinase inhibitors, medication use in high-risk patients, and the role of adjuvant matinev in surgery and therapy selection for GIST.

Explore the best study plans and techniques used by fellows in hematology/oncology for board exams. Discover personalized strategies and resources tailored to individual learning styles. Delve into essential video resources and question banks, with a spotlight on the ASH review series and hemonquestions.com for detailed explanations. Learn effective strategies that emphasize consistency, flexibility, and high-yield topics, ensuring success in real-world oncology scenarios.

Kickstarting with a warm reintroduction, the hosts share their passion for hematology and oncology. They delve into the deep, meaningful connections formed with patients, emphasizing the fulfillment this brings to their challenging roles. The discussion highlights the complexity of modern cancer care, focusing on innovative therapies like immunotherapy and the importance of research. They also explore various career paths within the field, showcasing the benefits of multidisciplinary collaboration and hinting at future resources for aspiring professionals.

Explore the classification of gliomas like oligodendrogliomas and astrocytomas, emphasizing the significance of glioblastoma multiforme (GBM). Learn about key markers like IDH1 mutation and treatment approaches for recurrent GVM. Dive into management strategies for gliomas and meningiomas in primary CNS tumors, highlighting the role of mutations, methylation, and grade differentiation in treatment.

Dive into the world of Chronic Lymphocytic Leukemia (CLL), where you'll learn about its often asymptomatic nature, especially in older adults. Discover the vital role of flow cytometry in accurate diagnosis and the significance of chromosomal abnormalities in prognosis. Explore treatment strategies, including the use of BTK inhibitors and combination therapies. Tune in for insights on managing complications and approaches for relapsed cases that take patient prognosis into account.