

Extend Podcast with Darshan Shah, MD
Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Episodes
Mentioned books

Nov 18, 2025 • 1h 12min
113. Dr. Karan Rajan: Why Gut Health Shapes Your Longevity
Dr. Karan Rajan, a GI surgeon and gut health expert with a following of over five million on social media, delves into the intricacies of the gut microbiome. He explains how gut health is fundamental to digestion, immunity, and even skin health. Topics include the significance of fiber diversity, the dangers of low-fiber diets, and the impact of fermented foods. Dr. Rajan also discusses microbiome testing, the influence of circadian rhythms, and practical strategies to rebuild gut health after antibiotics. Tune in for actionable insights on optimizing your microbiome!

Nov 13, 2025 • 1h 29min
112. Josh Clemente: Why Energy Crashes Keep Happening and How to Stop Them
In this engaging discussion, Josh Clemente, founder of Levels and a former SpaceX life support engineer, dives into the transformative power of continuous health monitoring. He shares how personal experiences led to the adoption of continuous glucose monitors, empowering individuals to take ownership of their health data. Josh explores the comparison of biomedical observability to engineering telemetry, the potential of multi-molecule monitoring, and the shift towards preventive healthcare. Learn how AI and real-time data can optimize personal biology and prevent chronic diseases.

14 snips
Nov 11, 2025 • 1h 15min
111. Dr. Amir Vookshoor: Neurosurgeon Secrets For Bulletproof Brain Health
Dr. Amir Vookshoor, a board-certified neurosurgeon and founder of NeuroVella Brain Spa, shares insights on optimizing brain health through a blend of modern neuroscience and holistic practices. He discusses how stress and trauma can rewire the nervous system and the benefits of neurofeedback and advanced techniques like plasmapheresis. Vookshoor emphasizes the importance of breathwork and sleep in brain maintenance, likening it to dental care, while exploring innovative therapies that could slow neurodegeneration. A fascinating journey into cutting-edge brain wellness!

Nov 6, 2025 • 1h 31min
110. Dr. Josh Axe: The Hidden Connection Between Faith, Emotion, and Aging
Dr. Josh Axe, a chiropractor and clinical nutritionist, dives into the fascinating intersection of ancient medicine and modern longevity research. He explores how principles from Ayurveda and Traditional Chinese Medicine can enhance healthspan and mitigate aging. The discussion touches on the emotional aspects of healing, chronic stress's impact on gene expression, and the vital role of gut health. Josh also emphasizes the importance of everyday habits and natural methods over mere protocols, while sharing insights on peptides, stem cells, and a holistic approach to wellness.

Nov 4, 2025 • 40min
109. Dr. Gladys McGarey: What 103 Years of Life Can Teach Us About Longevity
Dr. Gladys McGarey, a pioneering figure in holistic medicine and author, shares her incredible insights from 103 years of life. She emphasizes that true healing comes from love, purpose, and community, introducing her renowned 'Five L's'—love, life, laughter, labor, and listening. With anecdotes from her early life in India and a meeting with Gandhi, she highlights how compassion and energy shape well-being. McGarey encourages viewing setbacks as teachers and believes that nurturing the human spirit is the essence of medicine.

Oct 30, 2025 • 45min
108. Dr. Vonda Wright: Why Women Need a New Approach to Aging, and How to Start Now
Dr. Vonda Wright, a double board-certified orthopedic surgeon and author of Unbreakable, shares her expertise on active aging and preventive strategies for women. She emphasizes that proactive health measures should start in the 30s and 40s, well before menopause. Vonda discusses how declining estradiol affects bone and brain health, and highlights biomarkers like VO₂ max and grip strength to predict longevity. Her FACE framework outlines essential training pillars for preserving mobility and strength, ensuring women can thrive through midlife.

Oct 28, 2025 • 45min
107. Dr. Will Cole: Gut Issues and Anxiety? Functional Medicine Is Finally Connecting the Dots
In this discussion, Dr. Will Cole, a pioneer in functional medicine and author of 'Gut Feelings,' explores the intricate connection between gut health and anxiety. He explains how the gut-brain axis influences our emotional well-being and why traditional treatments often miss the mark. Dr. Cole emphasizes the importance of comprehensive testing for hidden issues like bacterial overgrowth and trauma, while advocating for practical healing tools such as journaling, EMDR, and breathwork to support nervous system health. Tune in for insights on balancing mental and gut wellness!

Oct 23, 2025 • 1h 15min
106. Siggi Clavien: Why Your Liver is Slowly Killing You (And You Don't Even Know It)
In this discussion, Siggi Clavien, a liver health specialist and founder of The Liver Clinic, reveals the hidden dangers of liver health. He explains how 70% of liver disease isn't related to alcohol, the risks associated with common medications like Tylenol, and why standard blood tests might overlook early liver damage. Siggi also discusses the rising epidemic of fatty liver disease, the impact of processed foods and environmental toxins, and the importance of liver scans over traditional testing. Tune in for eye-opening insights on how to improve and protect your liver!

Oct 21, 2025 • 1h 18min
105. Gabby Bernstein: Why Safety Is the Most Powerful Longevity Protocol
In a thought-provoking discussion, Gabby Bernstein, a #1 New York Times bestselling author and esteemed spiritual teacher, explores the crucial role that emotional safety plays in achieving longevity. She highlights how feeling safe reduces inflammation and supports healing, often overlooked in the quest for health. Gabby introduces Internal Family Systems (IFS) to address trauma and shares her four-step self-help check-in, emphasizing that spiritual practices coupled with functional medicine create lasting health transformations. Discover how the path to wellness starts with safety and emotional regulation.

Oct 16, 2025 • 1h 41min
104. Dr. Jeffrey Bland: The Science of Immune Rejuvenation and Aging in Reverse
Join Dr. Jeffrey Bland, the father of functional medicine and founder of Big Bold Health, as he unveils the latest breakthroughs in immune rejuvenation. Discover how chronic inflammation accelerates aging and why gut health is pivotal for a robust immune system. Bland reveals a fascinating 90-day nutrition protocol that can reduce immune aging by 47%. Tune in to learn about the power of polyphenols, the impact of diet on gene expression, and how lifestyle changes can lead to a younger, more resilient immune response!


