Paul and Howard talk about healthy aging, from cell death, to diet, to centenarians, and exercise in-between. Financial geek that he is, Paul sneaks in a little riff about pension fraud too. There is a fairly crap transcript here.Topics:Healthspan vs lifespan, squaring the curveCellular housekeeping and whether it can be catalyzedDiets -- good, bad, and simpleWhat we can learn from centenarian studies, and where are their flawsReadings and Books Mentioned:Muscle mass and longevitySquaring off the lifespan curve Metabolic health and our muscles, tendons, and jointsSupercentenarian and remarkable age records exhibit patterns indicative of clerical errors and pension fraudBios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

Paul and Howard talk about air, exercise, lung function, and breathing in an age of wildfires and coronavirus. There is a fairly crap transcript here.Topics:Viruses and exerciseA primer on lung function during exerciseHow much outdoor exercise is safe when air quality is lousyBest ways to limit your pollutant exposureRelated Readings:Can air pollution negate the health benefits of cycling and walking?Air Pollution–Mediated Susceptibility to Inflammation and Insulin Resistance: Influence of CCR2 Pathways in MiceShould You Stop Exercising During Wildfire Season?Ambient Particulate Air Pollution and Daily Mortality in 652 CitiesCompanies/Products Mentioned:Plume LabsIQAirBlue AirBios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

We got lots of questions on our recent episode about air, exercise, and wildfires, so here is a short, deeper dive into the topic. We gave Howard the episode off, so I have a special guest, Christopher T. Migliaccio, a Research Assistant Professor in Immunology at the University of Montana. His main research interest is how environmental particulates in the respiratory system affect pulmonary immunology, and he is doing ongoing work on the effect of wildfires on pulmonary function.  There is a Fairly Crap Transcript™ here. Topics:Lung immunology and the role of macrophagesThe medium-term health effects of multi-day exposure to smoke, based on a cohort study of Montana's 2017 wildfiresConsequences of particulate for lung infections, from influenza to coronavirus Related LinksChristopher T. Migliaccio main pageResearch profileAlveolar Macrophages in Lung Inflammation and ResolutionMontana 2017 wildfiresCreditsCrossing the Chasm Kevin MacLeod Licensed under Creative Commons: By Attribution 3.0 http://creativecommons.org/licenses/by/3.0/Wholesome by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/5050-wholesome License: http://creativecommons.org/licenses/by/4.0/Bios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

Learn about the evolution of shoulders, why rotator cuffs go awry, and the prevalence of issues in people over 45. Discover the future of fixing rotator cuff problems and the complexities of shoulder anatomy. Explore the vulnerability of rotator cuffs to degeneration and injury, highlighting tendinopathy and biomechanics.

Paul and Howard talk about surgical anesthesia with a special guest: Jon Bauman, Chief of Anesthesiology at St. John's Riverside Hospital in Westchester, New York.  There is a Fairly Crap Transcript™ here.Topics:What is anesthesia? Are you asleep? Where does your brain go? What do anesthesiologists do when patients are out? Local, regional, and general anesthesiaThe future of anesthesia, both in terms of technology and anesthesiologist careersRelated Readings:The Butchering Art, by Lindsey Fitzharris A history of anesthesiology, Wood Library-Museum of AnesthesiologyBios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

Paul and Howard talk about shoes and their consequences. There is a Fairly Crap Transcript™ here.Topics:Why do we wear shoes? The evolutionary history of the footThe anatomic consequences of shoe wearMistakes people make buying athletic shoesThe explosion is athletic shoe varieties, from minimalist shoes, to maximalist shoes, and everything in-betweenCommon shoe-related foot injuriesRelated Readings:Born to RunDaniel Lieberman's Skeletal Biology labA history of the running shoeKiss, God of ThunderBios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

Dr. Inigo San Milan, an expert in mitochondrial health, discusses the importance of mitochondria for longevity and athletic performance. The conversation covers topics such as differences in mitochondrial health between athletes and non-athletes, the benefits of Zone 2 training, and Dr. San Milan's experience as a fitness coach for a Tour de France winner.

Paul and Howard discuss the importance of muscle mass for longevity, addressing topics like muscle loss with age, preserving muscle tone efficiently, and overcoming the fear of injury through targeted training. They dispel misconceptions about resistance training and highlight the relationship between muscle mass, strength, and daily functionality in aging populations.

Paul and Howard take listener questions about strength, longevity, and fitness. There is a Fairly Crap Transcript™ here.Topics:How to stay motivatedWhat being fit meansHow to sneak in enough activityRelated Readings:Muscle mass, strength, and longevityWhich  Comes First, Cardio or WeightsBios:Paul Kedrosky is a frequently injured athlete who, when he isn't rehabbing, is also a venture investor. Howard Luks is a top sports orthopedic surgeon.Music & Disclaimers:Crossing the Chasm by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3562-crossing-the-chasm License: http://creativecommons.org/licenses/by/4.0/Marty Gots A Plan by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4992-marty-gots-a-plan License: http://creativecommons.org/licenses/by/4.0/Disclaimers apply and can be heard at the end of the episode.This is only an excerpt. To listen to the entire episode, as well as see show notes and full transcripts, subscribe at simplavida.com.

Exploring metabolic syndrome, its causes, and consequences; discussing how diet affects metabolic health and the rise in prevalence of the syndrome; insights on insulin resistance and early detection of metabolic syndrome