Inside Health

Trials of a cancer 'vaccine' have begun and presenter James meets Steve, one of the first patients to trial the new treatment, Steve remembers his shock at being diagnosed with colorectal cancer in his 40s and tells the story of how he became involved in this pioneering research into tackling cancer.The vaccine is based on the same mRNA technology as the Pfizer-BioNTech COVID-19 vaccine and James heads to the University of Cambridge to find out how the early work into cancer vaccines became the foundation for the rapid rollout of the covid vaccine. In the lab, molecular biologist Dr Anne Willis and immunologist Dr James Thaventhiran explain how the vaccine is personalised to target the unique make-up of an individual patients' cancer cells, and how if the trials are successful they could open the door to mRNA treatments being used to treat a wide range of diseases.Also, Imperial College London cyber security researcher Dr Saira Ghafur joins James in the studio to explain why healthcare is a growing target for cyber attackers and how we can prepare for the next one because, as Saira says, it really is a case of "when" not "if".Presented by James Gallagher Produced by Tom Bonnett with Hannah Robins Assistant Producer: Katie Tomsett Editor: Holly Squire

Mpox is spreading and it’s been classified a public health emergency by the World Health Organization. Presenter James Gallagher meets Professor Trudie Lang from the University of Oxford who has been working in the areas affected to discuss what it means for people in the countries it’s already reached and whether its spread can be stopped.James also puts your questions on statins to Professor Naveed Sattar, and we hear the story of Simon who works in the outdoors as a landscape manager. He was having bouts of severe illness and was struggling to understand what was behind it. The answer? He’d had successive bites from ticks and was having symptoms of an allergic reaction when he was eating meat. He had alpha gal syndrome, commonly known as a meat allergy. We hear how it’s caused debilitating changes to his life.We also hear from Consultant Immunologist Dr Rachael O’Brian who has been documenting the first case of alpha gal syndrome her team have been diagnosing at Frimley Park Hospital in Surrey.Presenter: James Gallagher Producer: Tom Bonnett Assistant Producer: Katie Tomsett Editor: Holly Squire

Richard was 10 when he started smoking, and by the age of 35, he had given up on giving up smoking. But thanks to vaping he quit, almost by accident, in just a few months. However, vaping has been in the spotlight recently, with the rise of disposable vapes and awareness of more young people starting to vape. So, is vaping a useful tool to help people get off of cigarettes, or is it a gateway for young people into smoking? We hear from young people about their experiences and thoughts on vaping. In the studio, Dr Sarah Jackson, Principal Research Fellow at UCL Alcohol and Tobacco Research Group, and Hazel Cheeseman, Deputy Chief Executive of ‘Action on Smoking and Health’, are with James to discuss. Plus, podiatrist Dr Ivan Bristow is on hand to advise why James and listener Linda have had a hard time getting rid of their verrucas for years. We find out exactly what the warts are and what options are available to help our body tackle them. Presenter: James Gallagher Producer: Hannah Fisher Assistant producer: Katie Tomsett Editor: Holly Squire

In a heartfelt tribute to Akira Endo, the inventor of statins, guests discuss his choice to prioritize diet and exercise over medication in his later years. Margaret McCartney and Naveed Sattar debate the effectiveness of lifestyle changes in lowering cholesterol and their impact on cardiovascular health. Dermatologist Dr. Alexandra Banner shares insights on treating sunburn and reveals surprising home remedies. The discussion also touches on the controversial topic of snus and its potential to enhance athletic performance.

From the Hay Festival, James and a panel of experts explain what we can all do to help ourselves age well. We discover what’s going on in our bodies when we age, the difference between biological and chronological age, as well as getting the audience moving for a physical test. James is joined by gerontologist Sarah Harper from the University of Oxford, biomedical scientist Georgina Ellison-Hughes from King’s College London, and doctor Norman Lazarus to understand how exercise, diet, and mental health all have a part to play in how we age. Presenter: James Gallagher  Producer: Gerry Holt Editor: Holly Squire

Professor Damian Bailey and James explore the impact of watching sports on physiological responses, discussing increased heart rate and stress hormones. The podcast also covers the spread of dengue fever in Europe by Asian tiger mosquitoes and the potential risks during the upcoming Olympic Games in Paris. Additionally, they analyze the current Covid situation and factors influencing virus waves.

James visits a pub in Liverpool with a group of alcohol researchers to explore the effects of alcohol on the body and brain. They discuss the risks of alcohol consumption, debunk myths, and emphasize moderation. The podcast also touches on exercise's impact on sleep, chocolate's effect on insomnia, and falling asleep to health podcasts. They delve into managing tinnitus at night and announce a break until summer.

The podcast discusses the rise of cancer cases among young adults, sharing personal stories and challenges in getting diagnosed. It also explores the potential impact of weight loss drugs on fertility and the interaction between medication and contraception pills. Additionally, it delves into the considerations for testing new medications on pregnant women and the broader implications for pregnancy.

Experts discuss causes of insomnia, when to seek help, and latest treatments. Insights on personal experiences, coping strategies, and impact of alcohol on sleep quality. Exploring individual sleep needs, consequences of chronic insomnia, and brain waste clearance during sleep. Tips on managing insomnia, importance of seeking help, and optimism for solutions.

Scientists are worried about ticks. They say they’re starting to pose more of a health risk here in the UK, as our climate warms and urban areas spill into green spaces. But what are ticks, what kind of disease can they cause – and how much of a problem are they? We go on a tick hunt in Richmond Park and then head back to the lab to meet the ticks we’ve collected. We find out why new species of ticks and new diseases could be coming our way - and what you can do to keep safe.Also this week, we answer your questions on the impact of noise on our health following our recent programme. And we delve into the fascinating world of measles. It’s the most contagious virus in the world – by a long way. What is it about this virus that makes it so spectacularly good at infecting us?Keep in touch with the Inside Health team at insidehealth@bbc.co.ukPresenter: James Gallagher Producer: Gerry Holt Editor: Martin Smith Production coordinator: Liz Tuohy