Age Well with Dr Sophie Shotter

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • The connection between good gut health and skin • The skin’s microbiome – should we really be double cleansing? • The impact of skin treatments such as Roaccutane / antibiotics • Gut health and longevity / cellular ageing • Probiotics (the strains you need) • Candida… and IBS • Spore based / soil based probiotics • The vaginal microbiome • Prebiotics • Digestive enzymes • Eating bread • Taking probiotics while on antibiotics • Gut health testing / Zoe / the SIBO test • Acupuncture • Fasting, autophagy, mitophagy • The vagus nerve • Cold water therapy Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: Research linking gut dysbiosis to acne, rosacea, eczema, psoriasis, and other skin conditions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916842/ Gut health and acne https://zoe.com/learn/gut-health-and-acne Two thirds of our immune system lives in our gut https://www.uclahealth.org/news/want-to-boost-immunity-look-to-the-gut A study that indicates isotretinoin (another name for Roaccutane) has no significant (negative) impact on gut microbes https://pubmed.ncbi.nlm.nih.gov/28689869/ Research suggests the health of our gut microbiome largely determines how we will age and the diseases we will either acquire or avoid. https://www.nature.com/articles/nature25973 PLUS https://link.springer.com/article/10.1007/s12602-021-09903-3#:~:text=Studies%20have%20shown%20that%20gut,disorders%20is%20also%20becoming%20apparent Re probiotics: the two main strains you want to look for are: lactobacillus and bifidobacterium. Within these two, there are a lot of different strains. https://www.symprove.com/ < Dr. Sophie's recommendation A healthy vaginal microbiome should be dominated by a good bacteria called lactobacilli, especially the species called lactobacillus crispatus. Some people say that Saccharomyces boulardii really helps candida – it’s a yeast that fights yeast but while it’s helpful for some, others don’t tolerate it well. Read more: https://www.optibacprobiotics.com/uk/professionals/latest-research/gut-health/probiotics-best-for-candida#:~:text=S.,from%20the%20digestive%20tract2%20. Fiona's acupuncturist: John Chadwick (Sidmouth, Devon): johnchadwick@ymail.com An interesting listen: https://podcasts.apple.com/gb/podcast/the-junk-food-doctor-this-food-is-worse-than-smoking/id1291423644?i=1000632239649 https://www.hollandandbarrett.com/the-health-hub/vitamins-and-supplements/supplements/inulin-powder-supplement/ https://www.verywellhealth.com/the-benefits-of-digestive-enzymes-89446 https://zoe.com/ SIBO testing is available in several places such as here: https://healthpath.com/sibo-breath-test/?utm_term=sibo%20test&utm_campaign=SIBO+-+Exact&utm_source=adwords&utm_medium=ppc&hsa_acc=5004928523&hsa_cam=6449023587&hsa_grp=77317475015&hsa_ad=382201416429&hsa_src=g&hsa_tgt=kwd-306464899573&hsa_kw=sibo%20test&hsa_mt=e&hsa_net=adwords&hsa_ver=3&gad_source=1&gclid=Cj0KCQiA67CrBhC1ARIsACKAa8QSdxixKMR9ftSiPCJVan_quuR1D9cn4X_LjE07Yn0Nzv0AmJOqj3EaAnAfEALw_wcB Vagus nerve ear massage https://www.youtube.com/watch?v=9uZ1rnKF5DU The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • Is acne on the increase (if so, why)? • Girls, women, hormones - and acne • Testosterone / HRT regimes • Cortisol • Dairy • GI loads in diet • The gut health connection • Skin care products • Fungal acne • Niacinamide • Budget skincare ranges • Soolantra • Roaccutane • Antibiotics • Spironolactone • In-clinic treatments • Scarring • DIM (diindolylmethane) • Emergency spot treatments • The mental health factor Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788264/ https://www.jaad.org/article/S0190-9622(16)30480-7/fulltext#sec4 https://www.health.com/condition/acne/stress-acne https://clinisoothe.com/?utm_source=google&utm_medium=cpc&utm_campaign=13952991541&gclid=Cj0KCQiAr8eqBhD3ARIsAIe-buPEDl7J_6KDoM_OwRxFMoC3U92ATvlSdQJH90NGnsCmsXT5wq45nk4aAj5bEALw_wcB https://www.aad.org/public/diseases/acne/causes/diet https://zoe.com/learn/gut-health-and-acne https://www.cerave.com/skincare/acne https://www.laroche-posay.co.uk/en_GB/effaclar-2 https://www.bioderma.co.uk/skincare/sebium https://www.nhs.uk/medicines/isotretinoin-capsules/ https://practicaldermatology.com/articles/2014-jan/on-dosage-and-diet-isotretinoin-101 https://www.rosacea.org/patients/causes-of-rosacea/demodex-mites-and-microbes https://www.bmj.com/content/381/bmj.p1114 https://aviclear.com/ https://www.allure.com/story/aviclear-review https://zitsticka.co.uk/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/#:~:text=Many%20studies%20showed%20high%20prevalence,psychiatric%20comorbidities%20in%20chronic%20diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/ Further studies and reading https://jddonline.com/articles/the-role-of-benzoyl-peroxide-in-the-new-treatment-paradigm-for-acne-S1545961613S0073X/#:~:text=Combining%20BP%20with%20a%20topical,resistant%20strains%20of%20P%20acnes. https://www.theguardian.com/fashion/2019/oct/05/the-best-emergency-spot-treatments https://www.theguardian.com/lifeandstyle/2011/aug/19/sali-hughes-acne-treatments The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • Squalane • Single ingredient products • Vitamin C (inc. stability and dose / formulations) • Niacinamide • Budget friendly vitamin C products • Exfoliating acids (inc. what Dr Sophie uses) • How to exfoliate • Hyaluronic acid • Serums - the lowdown • Dr Sophie’s favourites • Cult products • Alcohol denat • SPF (mineral and chemical) • Neck creams, decolletage, eye creams, night creams • Retinol – the explainer • New molecules and developments in skincare • Exosomes • Dr. Sophie’s skincare heroes • New business models / Beauty Pie • Multitasking skincare v single ingredient products • Skin cycling • Korean skincare • Dr Sophie’s routine • Can any skincare remove wrinkles? The data • A holistic approach Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: https://biossance.com/products/100-squalane-oil https://www.laroche-posay.co.uk/en_GB/toleraine-1?start=0&sz=24 https://www.paulaschoice.co.uk/clinical-ultra-rich-moisturizer/m5570.html?dwvar_m5570_size=fullsize&cgid=pregnancy-skincare&reviews=&pr_rd_page=1&aw_account=1510415071&aw_campaign=19592213249&aw_adgroup=&aw_creative=&aw_dev=c&aw_target=&&utm_content=performance_max&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM-cNYfOib6WC4dTz2P8-zmzBfKm7GXFJG5czLgQdm9NIIL8hKKKc9hoCxT8QAvD_BwE https://www.revisionskincare.co.uk/?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLMzsnmPxDtNDdrQn4jtjMDvshIja52__h9o6MQer4ZrRe67IqJmiBjhoCe7sQAvD_BwE https://skindiligent.com/products/vitamin-c-serum-in-oil https://www.medik8.com/products/c-tetra https://www.vichy.co.uk/en_GB/liftactiv-supreme-15-pure-vitamin-c-brightening-serum-20ml/VICUK-140.html https://www.neostrata.com/products/collections/restore https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?variant=44619262263570 https://www.vichy.co.uk/en_GB/mineral-89-hyaluronic-acid-hydrating-serum---hypoallergenic-for-all-skin-types/VICUK-014.html https://www.vichy.co.uk/en_GB/mineral-89-probiotic-serum/VICUK-135.html https://mederbeauty.com/products/hydra-fill-concentrate https://www.revisionskincare.co.uk/products/hydrating-serum https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html https://www.skinbetter.com/shop-skincare/product-category/antioxidants/alto-advanced-defense-and-repair-serum-M006.html https://www.skinceuticals.co.uk/en_GB/c-e-ferulic-vitamin-c-antioxidant-serum-for-visible-signs-of-ageing-30ml/S17.html https://www.esteelauder.co.uk/product/689/77491/product-catalog/skincare/repair-serum/advanced-night-repair-serum/synchronized-multi-recovery-complex https://www.clarins.co.uk/double-serum/C070400090.html https://www.drunkelephant.co.uk/gb/en/collections/serums/ Sophie references avoiding alcohol denat. Here’s a useful article from Paula’s Choice (referencing data and science): https://www.paulaschoice.co.uk/alcohol-in-skincare-the-facts The efficacy and safety of sunscreen use for the prevention of skin cancer - PMC (nih.gov) https://heliocare.co.uk/products/mineral-tolerance-fluid https://www.esthederm.com/en/suncare/by-range/solar-range.html https://www.laroche-posay.co.uk/en_GB/sun-care-face https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced https://www.skinbetter.com/shop-skincare/product-category/neck-care/techno-neck-perfecting-cream-M013.html The Medik8 range in three sections: https://www.medik8.com/collections/shop-by-retinol https://www.medik8.com/collections/shop-by-retinaldehyde https://www.medik8.com/collections/shop-by-retinyl-retinoate A retinol alternative if you’re pregnant: https://edit.sundayriley.com/alternatives-to-retinol-during-pregnancy/ https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html https://amp-uk.co.uk/exoe/ https://www.obagi.com/ Two new skincare launches to look out for: https://sentelabs.com/ https://www.biojuve.co.uk/ https://www.beautypie.com/ The ones Sophie always has in the rotation: https://www.revisionskincare.co.uk/products/d-e-j-daily-boosting-serum%E2%84%A2?_pos=1&_sid=35655adf0&_ss=r&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM1LXfuwrcGrGrOW05wulykZ99fQc6Nq6_IXid-51ppcNNNXS8nS5XhoCJMsQAvD_BwE https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html https://www.skinbetter.com/shop-skincare/product-category/eye-care/eyemax-alpharet-overnight-cream-M009.html https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced https://mederbeauty.com/collections/sheet-masks https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?_pos=2&_sid=4094c872b&_ss=r&variant=44619262263570 The alternatives to injectables: https://mederbeauty.com/products/myo-fix-concentrate?variant=44619261870354 https://revisionskincare.com/products/revox%E2%84%A2-line-relaxer-0-68-fl-oz https://www.skinbetter.com/shop-skincare/product-category/anti-aging/interfuse-intensive-treatment-lines-M005.html The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • LED masks – in-clinic versus at-home (and the data) • Sophie’s preferred at-home option • Different LED lights and what they do • The Dermalux Flex • LED hype v LED data • Budget options for LED • At home microcurrent devices • What microcurrent can and can’t do • Taking a multi-pronged approach with gadgets and injectables • Radiofrequency – at home versus in-clinic • The Body Balancer – and cellulite • Budget options • Jade rollers, gua sha, ice wands, rollers • Lymphatic drainage massage (and a recommendation) • Body brushing and bamboo tappers • Buccal massage • Micro-needling at home? • The cult behind of the Clarisonic • The skin’s microbiome • Dr Sophie’s recommendations Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, and individuals – all the links are here: https://dermaluxled.com/device/flex-md/ https://www.lustreclearskin.com/ https://www.newabeauty.co.uk/products/newa-starter-kit https://bodyballancer.co.uk/ https://www.charlottetilbury.com/uk/product/cryo-recovery-face-mask https://dimple-amani.com/ https://dimple-amani.com/products/kansa-wand The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr Sophie and Fiona discuss: • Collagen – a simple explainer • The different types of collagen • The real impact of collagen loss • How stress impacts collagen production (see links below) • What type of collagen should we use? • Dosage information and guidance • Brand recommendations • Hydrolysed collagen • Sources • Is vegan collagen a thing? • The role of vitamin C • Injectables • Other recommendations • Collagen banking • What you can do in-clinic • How long before you'll start seeing results? • When to take collagen • Can pregnant women take it? • Men and collagen • Face creams Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: An independent study from 2019 that found collagen supplements do show promise in terms of improving skin elasticity and dermal collagen density > https://jddonline.com/articles/dermatology/S1545961619P0009X More from Dr Sophie on collagen > https://www.getthegloss.com/beauty/collagen-supplements-how-to-know-your-collagen-burn-rate Dr Sophie’s recommendations: https://evernutri.com/products/evercol https://www.absolutecollagen.com/ https://feelingenious.com/ https://www.altrient.com/liposomal-vitamin-c https://www.doseandco.com/uk This is the collagen that’s only available through nutritionists (with a type 2) https://evernutri.com/products/omnicol%E2%84%A21-10-hydrolysed-collagen TO BUY, PLEASE USE THIS CODE: SophieSREvernutri The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr Sophie Shotter Dr Sophie and Fiona discuss: • Biohacking – an explainer • What’s evidence-based (or not)? • The role of influencers versus expert knowledge • Light therapy (infrared / LED) • Collagen supplements • Clean beauty • Micro needling • Oxygen therapy / hyperbaric oxygen • Skin cell therapy • Oestrogen • IV vitamin C and long COVID • NAD+ (brand linked in below) • Sleep • Vitamin D3 • Magnesium • Oura Ring (linked in below) • Glucose monitoring • Meditation • Nutrition and alcohol • Forest bathing • Fasting and Dr Mindy Peltz / John Hopkins (linked in below) • Perimenopause • Cryotherapy • Home DNA analysis • The Dutch test Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here: https://nuchido.com/pages/nad-supplements https://ouraring.com/ https://drmindypelz.com/ https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-and-how-does-it-work The content in this podcast is for general informational purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr Sophie Shotter Dr Sophie and Fiona discuss: • Health span over life span • How to measure your biological age (link below) • The longevity discussion in-clinic • Adjacent positive impacts of exercise • Good sleep hygiene • Dr Sophie’s evening routine… • … and supplements • Vitamin C’s link to collagen production (research below) • NAD+ • Magnesium • Vitamin D3 • Omega 3’s, inflammation and cognitive function (study below) • Vegan options with omega oils • Resveratrol • Metformin (details of study below) • Spermidine - and autophagy (brand linked in below) • Gut health and skincare (study below) • We can intervene in the ageing process (see Dr David A Sinclair site below) • Epigenetics • DNA tests that calculate our biological age • Telomeres – an explainer • Mental health and micro dosing (TED talk linked in below) • Meditation • Dr. Joe Dispenza (info below) Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here: The link between vitamin C and collagen https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C#:~:text=Specifically%2C%20vitamin%20C%20has%20been,response%20to%20photodamage%20(48) The link between omega 3’s, mood, and cognitive function https://bmjopen.bmj.com/content/9/6/e027167 Metformin https://fortune.com/well/2023/05/04/metformin-anti-aging-longevity-risks-side-effects/ Spermidine supplement https://oxfordhealthspan.com/#:~:text=Recommended%20by%20world%2Dleading%20longevity,concentrated%20Japanese%20wheat%20germ%20extract. The link between gut health and good skin https://www.sciencedirect.com/science/article/pii/S2352647515000155 Bio Kult probiotics https://www.bio-kult.com/ Symprove probiotic https://www.symprove.com/ Read about Dr David A Sinclair’s work https://lifespanbook.com/ Test your biological age https://glycanage.com/ ‘Why We Sleep’ by Matthew Walker https://www.waterstones.com/book/why-we-sleep/matthew-walker/9780141983769 TED talk on microdosing https://youtu.be/vQuuY9xmzjg?si=k85jak3T2YQW02PU Michael Pollan's How to Change Your Mind https://michaelpollan.com/books/how-to-change-your-mind-uk/#:~:text=%E2%80%9CHow%20to%20Change%20Your%20Mind%E2%80%9D%20is%20a%20calm%20survey%20of,%2Dreporting%2C%20a%20giant%20square. Dr Joe Dispenza https://drjoedispenza.com/ The content in this podcast is for general informational purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Conversations with the award-winning Dr Sophie Shotter covering the latest trends and developments in skincare, longevity, and aesthetics - bringing a science-based approach, and a focus on inner health and wellness.