
MCAT Basics (from MedSchoolCoach)
Join us as we detail MCAT exam topics. Each podcast covers several MCAT sections with lessons based on review material put out by the AAMC, such as practice tests and question banks. Sam also interviews MCAT tutors and experts who share tips on how premed students can raise their score to get into medical school.
Latest episodes

Jun 17, 2025 • 17min
Gas Phase
In this episode, guest host Alex Starks dives into Gas-Phase Concepts for the MCAT. He breaks down the physical properties of gases, explores the ideal gas law, and unpacks the ABCD laws of gases. Alex also covers key conditions that influence molecular collisions in gases and highlights the most important takeaways to help you excel in this section of the exam. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro: Med School Coach promotion and podcast introduction (02:01) Physical properties of gases (06:03) The ideal gas laws (09:40) Conditions that promote molecular collisions in gases (10:34) The ABCD gas law (13:02) The Van der Waals equation (14:33) Gas laws quiz (16:29) Key takeaways

Jun 12, 2025 • 32min
The Lymphatic System
In this episode, we focus on the lymphatic system, a crucial topic for the Bio/Biochem section of the MCAT. We'll cover the structure of the lymphatic system, including lymphatic vessels, lymph nodes, and major organs such as the bone marrow and thymus. You'll also learn about the system’s primary functions: returning fluid to the blood, supporting the immune system, and absorbing fats and fat-soluble nutrients. Hosts Sam Smith and Alex Starks break down how the lymphatic system plays a vital role in immunity, nutrient absorption, and fluid balance. By the end of this episode, you'll gain a deeper understanding of the lymphatic system's anatomy and physiology, helping you prepare for MCAT-related questions. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro: Med School Coach MCAT Tutoring Promotion (01:01) Episode Introduction: Lymphatic System Overview (01:07) Co-Host Introduction: Sam Smith and Alex Starks (01:19) Episode Outline: Structure and Functions of the Lymphatic System (02:39) Structure of the Lymphatic System: Vessels, Nodes, and Organs (04:06) Lymph: Composition and Role in the Body (04:44) Lymphatic Vessels and Their Role in Transport (06:50) Primary and Secondary Lymphoid Organs: Bone Marrow, Thymus, and Lymph Nodes (09:10) Bone Marrow and B-Cell Maturation (09:45) Thymus and T-Cell Maturation

Jun 10, 2025 • 49min
Psychological Disorders
In this episode, we dive into psychological disorders, a crucial topic for the Psych/Soc section of the MCAT. We’ll start by defining what a psychological disorder is, highlighting key concepts like significant stress and deviant behavior, and discussing how they’re classified using the DSM-5. You'll learn about various categories of disorders, including anxiety disorders, obsessive-compulsive disorders, trauma and stressor-related disorders, and more. We’ll explore the biopsychosocial and biomedical approaches to understanding these conditions, providing insight into the biological, psychological, and social factors that contribute to mental health issues. By the end of this episode, you'll have a comprehensive understanding of the different types of psychological disorders and how they are categorized and treated, helping you tackle related questions on the MCAT. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro: Med School Coach promotion and podcast introduction (01:03) Overview of Psychological Disorders: Episode topics and structure (02:13) Defining Psychological Disorders: Significant stress and deviant behavior (05:29) Biopsychosocial vs. Biomedical Approaches: Holistic vs. traditional perspectives (09:18) DSM-5 Classification of Psychological Disorders: Overview of main categories (10:37) Anxiety Disorders: Fear and anxiety beyond normal levels (16:43) Obsessive-Compulsive Disorder: Obsessions and compulsions explained (18:20) Trauma and Stressor-Related Disorders: PTSD and related disorders (19:19) Somatic Symptom Disorders: Physical symptoms causing mental distress (22:01) Bipolar and Related Disorders: Mood swings and differentiating Bipolar I and II

Jun 5, 2025 • 45min
The Respiratory System
In this episode, we cover the respiratory system, an important topic for the MCAT Bio/Biochem section. We'll go over the anatomy of the respiratory system, highlighting key structures such as the lungs, bronchi, bronchioles, and alveoli, and explain how they contribute to respiratory functions. You'll also learn about the main roles of the respiratory system, including gas exchange, thermoregulation, particle filtration, and maintaining blood pH. We’ll break down the mechanics of breathing, including the role of the diaphragm and intercostal muscles, and how pressure changes drive air into and out of the lungs. We also cover the importance of pulmonary surfactant in preventing alveolar collapse and how partial pressures influence gas movement. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro (01:02) Overview: Functions of the respiratory system (01:28) Main Functions: Gas exchange, thermal regulation, particle filtration, pH control (02:20) Upper Respiratory Tract: Nose, nasal cavity, sinuses, larynx, trachea (05:00) Lower Respiratory Tract: Lungs, bronchi, bronchioles, and alveoli (09:28) Airflow Pathway: How air travels through the respiratory system (10:23) Gas Exchange: Oxygenation and CO2 removal (11:27) Breathing Mechanics: Diaphragm and intercostal muscles (13:04) Pressure Differentials: How pressure changes drive airflow (15:01) Surface Tension in Alveoli: Importance of pulmonary surfactant (18:17) Lung Compliance and Elasticity: How lung tissue stretches and returns to shape (21:48) Gas Exchange Process: Partial pressures of oxygen and carbon dioxide (24:59) Partial Pressure Explained: Role in moving gases during respiration (30:31) Thermoregulation: Maintaining body temperature through respiration (35:59) Particle Filtration: Nasal hairs and mucous cilia system (39:44) pH Regulation: How breathing controls blood pH (41:18) Respiratory Control: Involuntary and voluntary mechanisms, brainstem functions

Jun 3, 2025 • 53min
DNA Mutations and Repair
In this episode, we focus on DNA mutations and repair, a key topic for the Bio/Biochem section of the MCAT. We'll cover the different types of mutations, including point mutations, insertions, and deletions, and explain how they occur due to replication errors or environmental factors like UV radiation. You'll also learn about the repair mechanisms that fix these genetic changes, such as direct reversal, mismatch repair, and base excision repair. We’ll also discuss how double-strand breaks are addressed through homologous recombination and non-homologous end joining. By the end of this episode, you'll gain a thorough understanding of how mutations happen and the processes the body uses to repair them, helping you prepare for related MCAT questions. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro (01:07) Overview of DNA Mutations and Repair (01:45) What is a Mutation? (02:30) Mutations During DNA Replication (03:29) DNA Polymerase Slippage: Causes duplication of repeated sequences in DNA (06:15) Mutations Before or After Replication: Caused by mutagens like radiation or chemicals (07:19) Mutagens vs. Carcinogens: Differences between agents that cause mutations and those that cause cancer (09:56) Types of Mutations: Overview of point mutations, insertions, and deletions (12:00) Frameshift Mutations: How insertions or deletions shift the reading frame (29:50) Chromosomal Mutations: Inversions and translocations (35:35) DNA Repair Mechanisms: Introduction to replication repair, mutation repair, and break repair (36:51) Proofreading by DNA Polymerase: Repairing replication errors (39:20) Direct Reversal DNA Repair: Enzymes directly fix damaged DNA (40:41) Mismatch Repair: Fixing base mismatches and insertion-deletion loops (43:25) Base Excision Repair: Correcting single-base mutations (46:03) Nucleotide Excision Repair: Fixing bulky DNA damage like pyrimidine dimers (47:56) Interstrand Cross-Link Repair: Repairing DNA strands covalently cross-linked together (50:27) Single-Strand Break Repair: Ligating broken DNA strands back together (51:16) Double-Strand Break Repair: Homologous recombination and non-homologous end joining (54:13) Summary of DNA repair mechanisms

May 29, 2025 • 42min
Social Institutions
In this episode, we focus on the structure and role of key social institutions for the MCAT Psych/Soc section. We'll break down the five major institutions—health and medicine, education, family, religion, and government—and explain how each shapes societal norms and individual behavior. You’ll learn about concepts like medicalization, the sick role, and how healthcare is delivered, as well as the hidden curriculum and educational segregation. We’ll also cover family structures, kinship types, and how religion influences social change. Lastly, we’ll touch on political systems and the difference between power and authority, all of which are important for the MCAT. By the end, you’ll be equipped to understand how these institutions impact society and approach related MCAT questions with confidence. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro (01:03) Introduction to Social Institutions (01:54) Definition of Social Institutions (04:24) Formal vs. Informal Institutions (05:03) Health and Medicine: Structure and Function (07:49) Medicalization and the Sick Role (09:56) Delivery of Healthcare (12:18) Illness Experience (13:59) Social Epidemiology (17:05) Education: Structure and Function (19:37) Educational Segregation and Stratification (24:03) Teacher Expectancy (25:06) Family: Structure and Function (28:46) Violence in the Family (29:26) Religion: Structure and Function (32:25) Religion and Social Change (35:43) Government and Economy: Structure and Function (37:11) Power vs. Authority (38:23) Types of Political Systems (41:06) Division of Labor

May 27, 2025 • 28min
Aromatic Compounds
In this episode, we break down aromatic compounds, a crucial topic for the Biochem and Chem/Phys sections of the MCAT. You’ll learn what makes a compound aromatic, how to identify them using Huckel’s Rule, and the difference between aromatic, antiaromatic, and nonaromatic compounds. Sam Smith covers key examples like benzene, toluene, and phenol, and explains their role in biological systems like DNA and the electron transport chain. With practical tips and MCAT-focused insights, you'll be ready to tackle questions on aromatic compounds with confidence. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Introduction and Med School Coach Promotion (01:03) Introduction to the Topic: Aromatic Compounds (02:08) Definition of Aromatic Compounds and Electron Delocalization (04:43) Explanation of Huckel’s Rule and Aromaticity Criteria (07:59) Introduction to Antiaromatic Compounds (09:58) Definition of Polycyclic and Heterocyclic Aromatic Compounds (12:02) Common Aromatic Compounds to Know: Benzene, Toluene, Phenol, Aniline (14:54) Properties of Aromatic Compounds: Physical, Stability, Fluorescence, Basicity (20:15) Aromatic Compounds in Biology: Amino Acids, DNA/RNA, Electron Transport Chain (28:14) Conclusion and Outro

May 22, 2025 • 31min
Aging
Aging is an essential topic for the MCAT, and in this episode, we’ll explore it from multiple angles. We start with the biological aspects of aging, including key processes like telomere shortening, cell senescence, and mitochondrial dysfunction—each providing insight into how and why cells age. From there, we dive into how aging impacts the brain, including the types of memory and cognitive functions that either decline or improve with age. Lastly, we’ll cover the sociology of aging, focusing on the life course theory, the social significance of aging, and demographic changes. Expect a comprehensive breakdown of these concepts, with real-world applications and examples to reinforce your understanding. Visit MedSchoolCoach.com for more help with the MCAT. Jump Into the Conversation: (00:00) Intro (02:30) Cellular markers of aging: Protein aggregation and telomere shortening (04:55) Exploring cell senescence and autophagy dysregulation (07:20) Mitochondrial dysfunction and its role in cellular aging (09:10) Deep dive into telomeres and the Hayflick Limit (12:30) Introduction to aging in the brain (13:45) Memory and cognitive functions that remain stable with age (15:30) Brain functions that improve as we age: Crystallized intelligence and emotional intelligence (17:00) Brain functions that decline with age: Episodic memory and processing speed (19:30) Causes of changes in brain function: Brain size, vasculature, and neurotransmitter levels (22:15) Introduction to the life course theory and its relation to aging (24:45) The social significance of aging in different cultures (26:00) The aging population and its impact on healthcare

May 20, 2025 • 32min
Personality
In this episode, we focus on personality and the theories relevant for the MCAT. We’ll cover key perspectives, such as psychoanalytic theory, humanistic theory, and trait theory, along with the influence of social cognitive and biological factors on personality development. You’ll get an overview of the different personality disorders, categorized into clusters like odd or eccentric behavior, dramatic or erratic behavior, and anxious or fearful behavior. You’ll also gain an understanding of specific disorders, including narcissistic personality disorder, antisocial personality disorder, and obsessive-compulsive personality disorder. Visit MedSchoolCoach.com for more help with the MCAT. Jump into the conversation: (00:00) Intro (01:01) Introduction to Personality (01:41) Defining Personality (03:27) Overview of Personality Theories (06:11) Psychoanalytic Theory: Id, Ego, and Superego (09:03) Humanistic Theory: Achieving Individual Potential (10:16) Trait Theory: Stable Traits Over Time (11:06) Five-Factor Model of Personality (12:08) Social Cognitive Theory: Learning and Cognition (13:18) Biological Theory: Genetic Influences on Personality (15:10) Behaviorist Theory: Environmental Shaping of Personality (16:39) Introduction to Personality Disorders (19:19) Cluster A: Odd or Eccentric Behavior Disorders (22:26) Cluster B: Dramatic, Emotional, or Erratic Behavior Disorders (26:13) Cluster C: Anxious or Fearful Behavior Disorders (28:24) OCD vs. OCPD: Key Differences (29:40) Overlap Between Personality Disorder Clusters

May 15, 2025 • 36min
Molecular Structure and Absorption Spectra
In this episode, we cover molecular structure and the key spectroscopy techniques you need to know for the MCAT. We'll explore the intricacies of Nuclear Magnetic Resonance spectroscopy, breaking down the chemical shifts and spin-splitting essentials for understanding hydrogen and carbon bonds in various compounds. You'll learn how to identify functional groups using Infrared (IR) spectroscopy and how mass spectrometry can help determine molecular weights and identify unknown compounds. We'll also touch on UV-Vis spectroscopy and its role in quantifying compounds based on absorption spectra. Visit MedSchoolCoach.com for more help with the MCAT. (00:00) Intro (01:50) Introduction to absorption spectra and molecular structure (01:52) Absorption spectroscopy and its applications (03:39) IR spectroscopy: Analyzing functional groups with infrared radiation (07:57) Key IR peaks to know for the MCAT (09:52) Visible light and its role in determining compound color (10:57) UV-Vis spectroscopy: Connecting visible and ultraviolet light for compound analysis (14:06) Quantifying compounds using UV-Vis spectroscopy and Beer's Law (16:48) Mass spectrometry: Determining molecular weight and identifying compounds (22:18) Interpreting mass spectrometry graphs and calculating molecular weight (26:44) NMR spectroscopy: Understanding molecular structure through proton shifts (31:23) Key NMR shifts to know for the MCAT (33:21) Spin splitting in NMR and the n+1 rule