MCAT Basics (from MedSchoolCoach) Organic Chemistry Mechanisms To Know
Sep 26, 2025
Dive into the essentials of organic chemistry for the MCAT! Explore nucleophilic substitution through SN1 and SN2 mechanisms. Discover the art of aldol condensation and the nuances of oxidation and reduction reactions. Learn about Fischer esterification and saponification processes, as well as key elimination reactions. Don't miss the vital IR and NMR values you need to ace your exam. Get ready to grasp these high-yield topics and enhance your test prep with clarity!
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Master SN1 vs SN2 Selection
- Memorize SN1 and SN2 mechanisms and when each applies.
- Practice drawing the two-step SN1 with carbocation and the concerted SN2 with inversion.
Why SN1 Is Two-Step
- SN1 proceeds via a carbocation intermediate and is rate-limited by carbocation formation.
- Expect two steps: leaving-group departure then nucleophilic attack.
Concerted SN2 And Inversion
- SN2 is concerted and occurs in a single step with backside attack.
- This concerted mechanism produces inversion of stereochemistry.