Top experts Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho discuss ApoB, a crucial marker for heart disease risk. They cover its impact on LDL particles, atherosclerosis, and longevity. The episode explores measuring ApoB, normal levels, causes of elevation, saturated fats, and reliability over LDL cholesterol.

Dr. Kellyann Niotis, a preventive neurologist, and Dr. Thomas Dayspring, a lipidologist, dive into the intriguing connection between cholesterol and dementia. They highlight vital preventive strategies for brain health, discussing the role of LDL cholesterol, genetic factors like the ApoE4 allele, and the significance of early lifestyle changes. With insights into personalized health strategies, they explore how managing cholesterol levels can be an effective way to reduce the risk of cognitive decline. Don't miss their tips on omega-3 fatty acids and new therapeutic approaches!

Renowned lipidologist Dr. Thomas Dayspring discusses the significance of Lipoprotein(a) in cardiovascular health, genetic inheritance patterns, drug development strategies for reducing Lp(a) levels, and emerging treatments. Topics include oxidized phospholipids, statins, PCSK9 inhibitors, genetic variations, and lifestyle considerations.

In this engaging discussion, lipidologist Dr. Thomas Dayspring and endocrinologist Dr. Karl Nadolsky delve into the intricacies of blood test results. They tackle cholesterol and cardiovascular health, highlighting the importance of different lipoproteins like ApoB. The conversation also unpacks the significance of testosterone levels and thyroid function in overall wellness. With a focus on understanding individual health metrics, they emphasize regular blood testing and lifestyle choices for optimal health.

Episode #252. In Part One of the blood lipids series, you learned what lipids are and how they work. In Part Two, Dr Thomas Dayspring returns to talk about the individualised testing you can get to understand where your lipids are now. Discover the tests you need, the ones you don’t, and when to start testing to protect yourself against atherosclerotic cardiovascular disease.We discuss: Intro (00:00) What is Lp(a), and why do you need it checked? (02:05) Does diet influence Lp(a)? (20:36) The oxidized phospholipid test (29:00) Early intervention and atherosclerosis screening for children (31:24) The tests are helpful in predicting cardiovascular disease risk (40:27) Discordance between ApoB and LDL-cholesterol (52:35) Normal range of ApoB levels for a healthy young person (1:03:14) Does atherosclerotic plaque ever disappear? (1:16:52) Triglyceride: HDL ratio vs ApoB test (1:22:15) Screening women in their 30s (1:29:31) Screening women in their 70s (1:37:23) What causes elevated ApoB (1:39:25) Do phytosterols help manage cholesterol? (1:58:55) Secondary prevention (2:07:08) The obviously misunderstood case of ApoB (2:20:45) Outro (2:22:35) Next week, we’ll discuss in detail the interventions you can make to optimise your lipids. Make sure to stay connected via my social links below so you don’t miss Part Three.The best place to connect with Dr Thomas Dayspring is on Twitter, @DrLipid. Learn more about Dr Dayspring’s career and current work on LinkedIn.Discover more insights and supporting studies in the full show notes.To assist with the digestibility of this content my team and I, along with Dr Dayspring, have added a bunch of illustrations and graphs to the video format of these episodes. So if you are visually inclined you can watch these episodes on our YouTube channel. Even if you prefer listening to the first time through audio, I highly recommend coming back for a second pass with the video versions. Get your copy of the Lipid Series Cheat Sheet at theproof.com/lipidseries. This comprehensive resource provides valuable insights on assessing your risk, preventing, and treating atherosclerotic cardiovascular disease (ASCVD), the leading cause of death worldwide. The PDF not only highlights key learnings from the 3-Part Lipid Series but also includes a 1-week meal plan designed to promote healthy cholesterol levels.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.Simon Hill, MSc, BSc (Hons)Creator of theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube or listen on Apple/SpotifyConnect with me on Instagram, Twitter, and FacebookNourish your gut with my Plant-Based Ferments GuideDownload my complimentary two-week meal plan and high-protein Plant Performance recipe book