Dr. Suzanne Devkota, Director of the Microbiome Research Institute, and Tim Spector, Professor of Epidemiology, delve into the fascinating world of gut bacteria and its crucial role in managing belly fat. They discuss how specific microbes can either support or hinder weight loss efforts and the complex relationship between visceral fat and immune health. Surprising insights reveal that the diversity of gut bacteria can impact overall well-being, and they share practical tips for improving gut health, including dietary changes and the benefits of fermented foods.

Episode #267. Join me for a deep dive into the influence of the gut microbiome on inflammation and metabolic disease. In this fascinating exchange with Dr Suzanne Devkota, we explore the role of the gut in these conditions, shedding light on food allergies, IBD, and obesity. You’ll learn the practical tips you need to nurture a healthy microbiome, as well as gain a better understanding of what we do – and don’t – know about this incredible system.Specifically, we discuss: Intro (00:00) The evolving field of microbiome research (02:13) Gut microbe on social media (09:32) Microbiome definition (12:48) Why the focus on gut bacteria? (13:55) Differences in Microbes (16:02) Microbial shifts and adaptations (18:45) Microbes perturbations (21:35) Human microbiome in evolution (23:54) Healthy microbiome and diversity (27:47) Is the microbiome the sole driver of metabolic diseases? (33:05) Dietary patterns and FODMAP intolerance (41:07) Saturated fat and gut health (49:15) Microbiome metabolites and heart disease risk (57:42) Inflammatory bowel disease (IBD) and dysbiosis (1:02:09) Food additives (1:12:29) Supporting the microbiome in IBD (1:15:29) Microbiome's interaction with fat cells (1:16:52) Short-chain fatty acids and appetite regulation (1:29:26) Practical tips for nourishing a healthy gut (1:31:05) Microbiome's interaction with Polyphenols (1:38:43) On supplements and fermented foods (1:39:15) Factors affecting gut health beyond nutrition (1:46:22) Outro (1:50:10) Connect with Dr Suzanne Devkota on Instagram and Twitter. Learn more about her research at http://www.devkotalab.com/thelab.Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at insidetracker.com/simon.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.Simon Hill, MSc, BSc (Hons)Creator of theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube or listen on Apple/SpotifyConnect with me on Instagram, Twitter, and FacebookNourish your gut with my Plant-Based Ferments GuideDownload my complimentaryTwo-Week Meal Plan and high protein Plant Performance recipe book

Suzanne Devkota, Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center, discusses the ineffectiveness of fasting and other diets, importance of dietary fiber, concerns about 'leaky gut,' and potential harm of food additives. They explore the impact of a certain ingredient on the gut microbiome and highlight the significance of avoiding nitrates, adding fiber, and considering the food matrix. The chapter also discusses the influence of chemical additives, alcohol, and different fibers on the gut microbiome and addresses the topic of fecal transplants and sequencing in gut microbiome analysis.

Dr. Suzanne Devkota, Director of the Human Microbiome Research Institute, discusses the link between gut health and diseases, the benefits of prebiotics and probiotics, and how to boost your immune system. The podcast also explores the relationship between human and animal microbiomes and the significance of blood biomarkers in health. The trend in gut microbiome research from association to mechanistic studies is emphasized.

In this episode Layne and Holly sit down with gut microbiome expert, Professor Suzanne Devkota.   Suzanne Devkota, PhD, is an assistant professor at UCLA as well as in the Cedars-Sinai Division of Gastroenterology investigating the role of diet in shaping the community of bacteria that live in our intestines (the "gut microbiome"). Her research into the effects of dietary fat on host-microbe interactions in inflammatory bowel diseases (IBD) led to some of the first mechanistic insights into why "modern" diseases such as IBD, diabetes and food allergies have rapidly increased over the past 50-100 years. Her ongoing research focuses on the role of sulfur-reducing bacteria on host immune responses and on counteractive nutritional therapies. Devkota teams with Cedars-Sinai physicians to combine clinical and basic research utilizing patient samples, in vivo conventional and gnotobiotic animal models, and sequencing- and culture-based microbial methodologies to investigate the molecular mechanisms underlying clinical phenomena. Her goal is to add a powerful new dimension to diagnosis and treatment through a better understanding of gut microbial contributions to disease.   Some of the topics we hit on in this episode include:   -Her education and how she got into gut microbiome research sort of by accident -The effects of different dietary modifications on the gut microbiome -Why the microbiome is so important -Probiotics vs prebiotics -Artificial sweeteners & their effects on the gut microbiome -The limitations in the different types of studies -The importance of fiber & dietary fiber diversity -Intermittent fasting -Her opinion on "gut health" products -Her recommendations for nutrition overall for a healthy gut   You can find Suzanne on Twitter @suzanne_devkota and at devkotalab.com   Get our new nutrition coaching app, Carbon Diet Coach, for iOS and android to get custom nutrition coaching for less than $10/month: https://joincarbon.com Get our books on how to lose fat: https://www.biolaynestore.com Take my online course "The Science of Nutrition": https://cleanhealth.edu.au/product/science-of-nutrition Get custom workouts by us for $12.99/month: https://www.biolayne.com/members/workout-builder   Find Layne and Holly on Instagram @biolayne and @hollytbaxter ---- Post-production by Jim McDonald (@thejimmcd) and David Margittai (inpostmedia.com)   © 2020, Biolayne LLC. All rights reserved.