Colleen Cutcliffe, expert in molecular biology and co-founder of Pendulum Therapeutics, discusses the complexity of the microbiome, the role of probiotics and prebiotics, the importance of a high-fiber diet, the potential of fecal microbiota transplant (FMT), and the challenges in manufacturing and maintaining bacteria strains. She also explores the role of acromancia in the gut microbiome, the efficacy of probiotics in improving GI symptoms, and the impact of high fiber and high polyphenol foods on gut health.

This week’s conversation is with Dr. Colleen Cutcliffe, the CEO and Co-Founder of Pendulum Therapeutics.Colleen’s extensive background includes a doctorate in Biochemistry and Molecular Biology from Johns Hopkins University, and over 20 years of experience managing and leading teams in biotech, pharma, and academia.In 2013, Colleen left her position as Senior Manager of Biology at Pacific Biosciences to start Pendulum, a company on a mission to improve health through first of its kind research and development in the gut microbiome.Pendulum’s next generation probiotics are pioneering ways for people to transform their health and wellness by unlocking the power of the gut microbiome.I’ve been studying gut health and the microbiome for a long time now, and it’s clear that Pendulum is on the forefront of creating meaningful change for people.I was fascinated to learn more about the topic from Colleen, and I hope you leave this conversation with a better understanding of the gut microbiome, and some applied insights on how improving your gut health can improve your life.-----You can also watch this - and every - conversation on our YouTube channel.Connect with us on our Instagram.For more information and shownotes from every episode, head to findingmastery.net.-----Please support our partners!We're able to keep growing and creating content for YOU because of their support. We believe in their mission and would appreciate you supporting them in return!!To take advantage of deals from our partners, head to http://www.findingmastery.net/partners where you'll find all discount links and codes mentioned in the podcast.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Wild Health Podcast, we sit down with Colleen Cutcliffe, CEO and co-founder of Pendulum, to explore the power of the microbiome for optimal health. We learn about the significance of keystone bacteria, probiotics' impact on chronic illness and metabolic health, and practical tips for incorporating Akkermansia into your routine. Discover the relationship between high fiber diets, polyphenols, and increasing Acromancia levels, as well as the philosophy of selling directly to consumers and the limitations of FDA approval.

Dr. Colleen Cutcliffe, CEO of Pendulum Therapeutics and an expert in biochemistry, reveals a groundbreaking probiotic that stimulates natural GLP-1 production. She shares why traditional GLP-1 drugs like Ozempic are being challenged by this new approach. Listeners learn about impressive trial results showing reduced food cravings and the complexities of probiotic production. Colleen also discusses the importance of keystone strains in the microbiome and the potential benefits for managing obesity and diabetes.

Colleen Cutcliffe, Ph.D., discusses the power of GLP-1 probiotics for weight management and overall well-being. Topics include natural ways to stimulate GLP-1, the role of microbiome in regulating cravings, the impact of probiotics on gut lining health, and the connection between GLP-1 and longevity.

Dr. Colleen Cutcliffe, the CEO and Co-Founder of Pendulum Therapeutics, shares her remarkable journey from academia to health innovation. She discusses the resilience needed to overcome setbacks and emphasizes the importance of teamwork in entrepreneurship. Colleen reflects on handling rejection and how it fueled her personal growth, even sharing a story of her near academic failure. Throughout the conversation, she highlights the significance of authenticity and community support in achieving success while changing the health industry.

Dr. Colleen Cutcliffe, a biochemistry expert with over 25 years of experience and CEO of Pendulum, dives into gut health's vital role in overall well-being. She discusses how our microbiome changes over time and its surprising link to mood. The importance of diversity in gut bacteria and the specific strain, Akkermansia muciniphila, is highlighted for maintaining gut lining and metabolism. Colleen also tackles the impact of antibiotics on gut health and reveals how probiotics could aid in diabetes management and blood sugar control.

Dr. Colleen Cutcliffe discusses antibiotic impact on gut microbiome, Akkermansia's benefits, and gut-brain communication's implications on neurological disorders like Parkinson's and Alzheimer's. They explore the evolution of antibiotics, recent discovery of Akkermansia, and neurons in the gut communicating with the brain. The podcast sheds light on preserving gut microbiome diversity, the role of Acromancia in maintaining gut health, and the impact of hormonal changes on gut health in menopausal women. Additionally, it explores the gut-brain connection, microbiome's influence on cravings and neurological conditions, and the immune-supporting role of butyrate in combating inflammation and supporting colonocytes.

Dr. Colleen Cutcliffe, CEO of Pendulum, discusses the gut microbiome's role in metabolic health, antibiotic impacts, probiotics, and continuous glucose monitors. She highlights Pendulum's glucose control benefits for diabetes and the synergy with GLP-1 medications for improved outcomes.

Dr Colleen Cutcliffe, a co-founder of Pendulum, discusses the importance of Akkermansia muciniphila in gut health and disease prevention. She explains the role of this keystone strain in maintaining the gut lining and ongoing research on its regulation. Furthermore, she explores how Akkermansia promotes mucus production, regulates glucose control through GLP one stimulation, aids in weight loss, and metabolizes fiber into butyrate.