Nutrition Facts with Dr. Greger The Anti-Aging Pathways of AMPK
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Nov 21, 2024 Discover the fascinating role of AMPK, a key enzyme acting as a universal fuel gauge in our bodies. Learn how this regulator impacts aging and promotes fat metabolism. Exercise emerges as a natural method to boost AMPK activation, enhancing mitochondrial function and overall health. Plus, dive into the protective benefits of AMPK for mitochondrial health and age-related diseases. The conversation also touches on the effects of metformin, a drug that activates AMPK, highlighting its potential in longevity.
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AMPK: The Fat Controller
- AMPK, found in plants and animals, acts as a fuel gauge, activating when energy is low.
- It switches the body from storing to burning fat, earning it the nickname "fat controller".
AMPK and Longevity
- AMPK activation declines with age, hastening aging when reduced and extending lifespan when boosted.
- Boosting AMPK can mimic calorie restriction's effects, making it a target for longevity research.
AMPK, Exercise, and Mitochondria
- Exercise naturally boosts AMPK, leading to fat burning and mitochondrial biogenesis (creation of new mitochondria).
- AMPK activators, now banned in sports, can mimic exercise, enhancing endurance.
