324: How Mouthwash, Fluoride, and Antacids are Slowly Destroying Your Health | Nathan Bryan, PhD
Sep 6, 2023
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Dr. Nathan Bryan, molecular medicine leader, discusses the importance of nitric oxide, therapy for mental health, negative effects of mouthwash on oral microbiome, significance of electrolytes, iodine deficiency, impact of alcohol on oral microbiome, and role of nitric oxide in immune function.
Optimal nitric oxide levels are crucial for overall health and can be disrupted by factors such as antiseptic mouthwash, fluoridated toothpaste, and antacid medications.
Nitric oxide deficiency is linked to chronic diseases including cardiovascular disease, diabetes, autoimmune diseases, and Alzheimer's, and addressing this deficiency is essential for preventing the progression of age-related conditions.
Nitrites in processed meats, when consumed within recommended limits and in the presence of certain compounds like vitamin C and E, do not pose a significant health risk.
Deep dives
The importance of nitric oxide in our health
Nitric oxide is a critical molecule for both short-term and long-term health. It acts as a signaling molecule and is most commonly known for its role in vasodilation, which helps regulate blood flow and circulation throughout the body. Low nitric oxide levels have been linked to various health conditions, such as heart disease, sexual health issues, Alzheimer's disease, high blood pressure, and metabolic health problems. Factors that can interfere with optimal nitric oxide levels include the use of antiseptic mouthwash, fluoridated toothpaste, and antacid medications. Strategies to boost nitric oxide production include consuming foods high in nitrate, ensuring the presence of the right oral bacteria, and maintaining stomach acid production.
The connection between nitric oxide and chronic diseases
Nitric oxide plays a crucial role in mitigating the hallmarks of chronic diseases, including decreased blood flow, inflammation, oxidative stress, and immune dysfunction. These four factors contribute to a wide range of chronic conditions such as cardiovascular disease, diabetes, autoimmune diseases, and Alzheimer's. Erectile dysfunction is often an early sign of nitric oxide deficiency and should be taken seriously, as it indicates potential vascular dysfunction in other organs as well. Recognizing and addressing nitric oxide deficiency is essential to prevent the progression of age-related chronic diseases.
The misconceptions surrounding nitrites in processed meat
Sodium nitrite, which is added to processed meats as a curing agent, has been unfairly demonized. It serves as a preservative, preventing food spoilage and the growth of harmful bacteria. Nitrites in cured and processed meats do not directly cause cancer or other diseases. The formation of nitrosamines, potentially harmful compounds, is only possible under specific conditions, such as high heat and the presence of certain secondary amines. However, the presence of vitamin C, polyphenols, and vitamin E in cured meats inhibits nitrosamine formation. Consequently, there is no evidence to support the claim that nitrites in processed meat pose a significant health risk.
Strategies to enhance nitric oxide levels
To naturally enhance nitric oxide levels, it is recommended to consume a balanced diet rich in nitrate-containing foods, such as leafy greens. Maintaining a healthy oral microbiome by avoiding excessive use of mouthwash and fluoride-containing products is also crucial. Additionally, ensuring adequate stomach acid production can be achieved by supplementing with iodine, zinc, and B vitamins. Pre-workout supplements that claim to boost nitric oxide levels often lack the necessary components for effective nitric oxide production. Instead, supplementing with products that provide bioactive nitric oxide, such as a lozenge or a fermented beetroot powder, can be more beneficial in optimizing nitric oxide levels.
Importance of Oral Microbiome for Blood Pressure
Hypertension can be a sign of oral dysbiosis, according to the podcast episode. The disruption of the oral microbiome, caused by the use of mouthwash and drinking alcohol, can lead to high blood pressure. Restoring the ecology of the oral microbiome can help normalize blood pressure. The episode also highlights how certain hygiene practices during the COVID-19 pandemic, like using mouthwash and hand sanitizers, may have compromised the oral microbiome and made individuals more susceptible to infection.
The Role of Nitric Oxide in Health
Nitric oxide plays a crucial role in various aspects of health. The podcast episode discusses how nitric oxide is beneficial for cardiovascular health, immune function, and inflammation regulation. The deficiency of nitric oxide can lead to increased vulnerability to COVID-19 and other infections. The episode emphasizes the importance of maintaining adequate nitric oxide levels by engaging in physical exercise, consuming nitrate-rich foods like dark leafy greens, and receiving sunlight exposure or red light therapy. It also provides insights into the limitations of medications such as Viagra for improving sexual function and highlights the role of nitric oxide in this area.
Dr. Nathan Bryan is an international leader in molecular medicine and nitric oxide biochemistry. He’s been involved in nitric oxide research for the past 20 years, and his many seminal discoveries have resulted in dozens of US and international patents and improved patient care worldwide.
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