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Acid-Base Disorders

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Feb 13, 2023
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INSIGHT

Acid-Base Disorder Classification

  • Acid-base disorders involve acid generation, buffering, and pH regulation (7.35-7.45).
  • Disorders are classified as respiratory/metabolic and acidosis/alkalosis, with mixed presentations possible.
ADVICE

GOLD MARK Mnemonic

  • Use the GOLD MARK mnemonic for anion gap acidosis.
  • This helps recall causes like glycols, oxaproline, lactate, D-lactate, methanol, aspirin, renal failure, ketoacidosis.
ADVICE

Five-Step Approach to Acid-Base Disorders

  • Use a five-step approach to analyze acid-base disorders.
  • Consider pH, primary disturbance (respiratory or metabolic), anion gap, expected compensation, and delta delta.
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