The Knowledge Project with Shane Parrish cover image

The Knowledge Project with Shane Parrish

#136 David Sinclair: Reversing the Aging Process

May 3, 2022
01:33:43

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Quick takeaways

  • Certain types of stressors, like exercise and exposure to heat, can activate biological defenses and improve longevity.
  • Taking resveratrol supplements can boost the activity of SIRT1, a longevity-associated protein.

Deep dives

Adversity and Stress on the Body

Exposing the body to certain types of stress and adversity, such as through exercise, saunas, and hot tubs, can activate biological defenses and improve longevity. By stimulating heat shock proteins and inducing the production of brown fat, these stressors can have positive effects on cardiovascular health and metabolism.

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