Choline: The Underappreciated Essential Nutrient with Chris Masterjohn PhD
Nov 12, 2019
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Chris Masterjohn PhD discusses the importance of choline as an essential nutrient, its role in reducing fatty liver, dietary sources, and methylation. He emphasizes the necessity of sufficient choline intake, especially during pregnancy. The podcast also tackles the TMAO controversy, optimizing folate status, and addressing MTHFR SNPs with creatine, B2, choline, and glycine.
Choline is essential in preventing fatty liver disease from various causes like alcohol and sugar.
Choline supplementation can reverse fatty liver disease, emphasizing its critical role in liver health maintenance.
Choline-rich foods like liver, egg yolks, nuts, and cruciferous vegetables are vital for supporting liver health, especially during pregnancy and breastfeeding.
Deep dives
Choline Prevents Fatty Liver in Humans
Research revealed that Choline is critical in preventing fatty liver disease triggered by various causes like alcohol, sugar, and more. Choline plays a crucial role in producing phosphatidylcholine, vital for exporting triglycerides from the liver. This highlights Choline's significance in maintaining liver health.
Recognition of Choline as an Essential Nutrient
Choline, although acknowledged as an essential nutrient in humans about 20 years ago, was found to be crucial in preventing fatty liver in individuals on intravenous total parenteral nutrition. Choline supplementation was observed to reverse fatty liver disease, shedding light on its importance.
Choline's Role in Mitigating Fatty Liver Effects
Choline's effectiveness in alleviating fatty liver caused by various factors like alcohol and sugar was evident. Its necessity for producing phosphatidylcholine, a key component in exporting triglycerides from the liver, underscores Choline's role in combating fatty liver issues.
Choline Recommendations for Fatty Liver Prevention
The significance of Choline intake in preventing fatty liver in individuals, especially during pregnancy and breastfeeding, is crucial. Adequate consumption of Choline-rich foods like liver, egg yolks, nuts, and cruciferous vegetables can help support liver health.
Factors Influencing Fatty Liver Disease
Research shows that Choline plays a pivotal role in preventing and managing fatty liver disease. Understanding the interactions between nutrients like Choline, B vitamins, and protein can offer valuable insights into optimizing liver health and preventing fatty liver issues.
Chris Masterjohn, PhD currently spends time on nutrition education, conducting independent research and consulting. He has deep and personal experiences with the power of food, movement, and mindfulness to support health and well-being.
• How choline was recognised as an essential nutrient. (6.35)
• Why choline reduces fatty liver. (11.52)
• Dietary sources of choline and its relationship with betaine. (16.31)
• Why the RDI for choline may not be enough. (20.53)
• The relationship between methylation and choline. (24.49)
• How to assess someone’s choline, B12 and folate status. (26.57)
• The importance of choline in pregnancy and infancy. (36.09)
• Teasing out the TMAO controversy. (41.17)
• Optimising folate status: Interpreting testing and intake. (51.10)
• Beyond folate forms: Addressing MTHFR SNPs with creatine, vitamin B2, choline and glycine. (53.45)
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