Science Friday How ‘Super Agers’ Stay Sharp And Active Longer Than Their Peers
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Jun 19, 2025 
Join cardiologist Eric Topol, a pioneer in longevity research, and neuroscientist Emily Rogalski, who leads studies on healthy aging, as they demystify the secrets of 'super agers.' They explore how social connections and engaging activities boost cognitive health in older adults. Discover the fascinating traits of these remarkable individuals who thrive into their 80s and 90s. The conversation highlights lifestyle interventions essential for promoting mental acuity and the challenges seniors face as they navigate the healthcare system.
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Ira Flatow's Super Ager Family
- Ira Flatow's mother lived to over 99 and never felt old despite her age.
- She stayed mentally sharp and socially active, including debating over Scrabble cards for a centenarian friend.
Lifestyle Over Genes in Super Agers
- Most super agers do not have genetic advantages; lifestyle factors primarily distinguish them.
- They show high immune system resilience which is not directly visible from genome sequencing.
Immune System Balance Is Key
- Super agers maintain balanced immune responses, avoiding excessive inflammation.
- This balance helps prevent cancers, cardiovascular disease, and Alzheimer's-related brain protein accumulations.
