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ACR Journals On Air

Immunology for the Rheumatologist: The Devil Is in the Details

Oct 29, 2024
David S. Pisetsky, a Professor at Duke University and lupus pathogenesis expert, dives deep into systemic lupus erythematosus (SLE). He uncovers how antinuclear antibodies and active DNA interplay to trigger inflammation. The podcast explores various immune responses, from the historical LE cell discovery to the complexities of cell death mechanisms. Pisetsky also discusses the genetic factors influencing autoimmunity and offers insights into effective scientific writing, blending storytelling with rigorous research to improve communication in the field.
51:03

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Quick takeaways

  • The historical discovery of antinuclear antibodies (ANA) in lupus has significantly shaped our understanding of autoimmune diseases and their treatments.
  • Recent findings highlight the complex role of DNA in immune responses and kidney inflammation in lupus, revealing several potential therapeutic targets.

Deep dives

Highlights of ACR Convergence 2024

ACR Convergence 2024 will take place in Washington, D.C. from November 14th to 19th, bringing together rheumatology professionals from around the world. Attendees can expect a range of insightful sessions that delve into groundbreaking scientific advancements in the field of rheumatology. Social events like the Knowledge Ball, Thieves Market, and Image Competition offer opportunities for networking and collaboration. The event aims to enhance learning and engagement among rheumatologists, fostering a global community of practice.

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