
Immunology for the Rheumatologist: The Devil Is in the Details
ACR Journals On Air
Nucleases and Autoimmunity Unraveled
This chapter explores the impact of specific nucleases, particularly DNases, on autoimmune diseases like lupus, highlighting their genetic implications and deficiencies. It examines the relationship between preclinical autoimmunity, immune tolerance mechanisms, and factors influencing the progression to clinical manifestations.
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