Docs Who Lift
NAD and NMN with Dr. Charles Brenner
Feb 12, 2025
Dr. Charles Brenner, an expert on NAD metabolism and longevity supplements, joins the conversation to break down the science behind NAD and NMN. He explains how NAD coenzymes are crucial for energy metabolism and discusses their decline with age. The chat dives into the misconceptions surrounding these supplements and critiques popular longevity claims made by figures like Andrew Huberman and Peter Atiyah. Brenner emphasizes the importance of a healthy lifestyle over reliance on unproven treatments, making it clear that foundational health practices are essential.
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Quick takeaways
- Supporting NAD metabolism through proper nutrition and lifestyle is more beneficial for longevity than solely relying on supplements like NMN.
- Many claims about NAD-related supplements are often exaggerated, highlighting the importance of scientific evidence over marketing in the health industry.
Deep dives
Understanding NAD and Its Role in Longevity
NAD coenzymes, specifically NAD+ and its derivatives, play a crucial role in cellular energetics and metabolism. They are responsible for transferring high-energy electrons from food to the mitochondria, ultimately producing ATP, the energy currency of cells. As people age, NAD levels decline, affecting metabolism and cellular repair processes. Research indicates that supporting the NAD system can help mitigate some effects of aging and metabolic stress.
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