Docs Who Lift NAD and NMN with Dr. Charles Brenner
Feb 12, 2025
Dr. Charles Brenner, an expert on NAD metabolism and longevity supplements, joins the conversation to break down the science behind NAD and NMN. He explains how NAD coenzymes are crucial for energy metabolism and discusses their decline with age. The chat dives into the misconceptions surrounding these supplements and critiques popular longevity claims made by figures like Andrew Huberman and Peter Atiyah. Brenner emphasizes the importance of a healthy lifestyle over reliance on unproven treatments, making it clear that foundational health practices are essential.
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NAD Coenzymes' Role
- NAD coenzymes are crucial for cellular energy and biosynthesis.
- They act as electron carriers, converting fuel into ATP and supporting macromolecule creation.
NAD and Aging
- Metabolism and repair capacity decline with age.
- NAD levels decrease in many cell types as we get older.
NAD's Role in DNA Repair
- NAD is vital for DNA repair after metabolic stress like sunburns.
- The enzyme PARP1 uses NAD to repair damaged DNA.