Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution.Learn:Why she wrote the book.The top 3 things to know when starting a GLP-1 medicine.Also hear the top criticism from Drs. Karl and Spencer. You will laugh.Click here to get the bookIf you're on a GLP-1 currently and want to switch to Dr. Spencer's new clinic, Click Here

Delve into the intriguing concepts of microdosing GLP-1 receptor agonists and the latest results from a new weight loss drug. Discover the balance between ethical medication access and corporate practices in healthcare. Hear about the eccentric quest for longevity and the disparities in medication availability. Explore the implications of microdosing terzepatide on inflammation versus weight loss. Unpack the ethical concerns surrounding cosmetic weight loss medications and the importance of responsible pharmaceutical practices.

Dr. Lauren Colenso-Semple, a PhD researcher specializing in exercise and menstrual cycles, shares her expertise on how menstrual phases should influence workout plans. She discusses the impact of hormone fluctuations on resistance training and the need for customized approaches as women experience their cycles differently. Myths surrounding hormonal contraceptives are debunked, while the significance of strength training for women is emphasized. Dr. Colenso-Semple advocates for more tailored fitness regimens that consider these unique physiological changes.

The podcast dives into the results of the Surmount 5 trial, comparing Zepbound and Wegovy for weight loss. The discussion highlights the benefits of these medications, including cardiovascular effects and safety profiles. A fascinating study on GLP-1 medications revealing reduced alcohol consumption adds an intriguing angle. The risks of misusing compounded GLP-1s are also examined, drawing attention to patient safety and regulatory issues. Finally, there’s a lighthearted critique of societal attitudes towards obesity treatment and the role of big pharma.

Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, dives deep into the complexities of diabetes classifications. She discusses the intricate types of diabetes, including monogenic forms, and the challenges in diagnosing lean individuals. The conversation addresses the usefulness of Continuous Glucose Monitors (CGMs) and the potential benefits of low-carb diets for certain patients. With insights on managing diabetes beyond lifestyle factors, Dr. Misra emphasizes the need for personalized treatment strategies.

Josh Umbehr, a physician and expert in direct primary care, shares fascinating insights on revolutionizing healthcare delivery. He highlights how cutting out middlemen can significantly reduce costs for lab tests and medications. The discussion dives into the inefficiencies of traditional insurance models, advocating for a more direct doctor-patient relationship. Umbehr emphasizes the benefits of simplified pricing and the need for innovative solutions to improve chronic disease management, making healthcare both affordable and effective.

Discover the latest three-year study on tirzepatide, revealing its impact on weight loss and the challenges of maintaining it long-term. Dive into the side effects like nausea and pancreatitis, but see how they taper off over time. Uncover the potential of semaglutide in easing knee pain for those with osteoarthritis. Enjoy some humorous political musings, imagining a 'buff doctor' running for office while blending health and society's perceptions. It's a mix of science, laughter, and insights into modern weight management!

Dr. Andrea Love, an immunobiologist and social media influencer, joins the discussion on health myths and the controversial 'Make America Healthy Again' movement. They explore the complexities of America's food environment and raw milk debates, emphasizing the need for pasteurization for safety. The conversation critiques health guidelines and advocates for balanced diets over misleading wellness claims. Lastly, they delve into the factors affecting COVID-19 outcomes, challenging oversimplified narratives on metabolic health.

Dive into the fascinating world of cortisol, the hormone at the center of health discussions. Discover its essential functions, from regulating blood pressure to metabolism, and learn why it's often misunderstood. The hosts tackle common myths about cortisol, debunking fears over exercise-induced increases. They also share personal tales about cortisol testing, navigating the complexities of health decisions. With humor, they explore the extremes athletes go to manage stress and nutrition while advising against misleading health claims.

Drs. Karl and Spencer discuss their ideal healthcare delivery system.Learn:Spencer's journey building and selling Sequence and what he wants to do next.How Dr. Karl believes healthcare should be and what he's doing next.Click here to get on Dr. Spencer's waitlist