Unraveling Pellagra and NAD+ Supplements

This chapter examines the historical impact of pellagra due to dietary deficiencies in the southeastern United States and explores the evolution of understanding related to nicotinamide riboside (NR) as a dietary supplement. It critically analyzes the misconceptions surrounding popular supplements for aging, delving into the science of NAD coenzymes and their role in health and disease, while emphasizing the importance of a healthy lifestyle. The discussion also highlights ongoing research on NR's benefits in various health contexts, addressing regulatory challenges and best practices in supplementation.