The Joe Rogan Experience #1551 - Paul Saladino
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Oct 16, 2020 
Dr. Paul Saladino, a physician and board-certified nutrition specialist, discusses the science behind the carnivore diet and its benefits. He emphasizes the nutritional value of organ meats and the philosophy of 'nose to tail' eating. Saladino critiques modern agricultural practices while advocating for the sustainability of grass-fed beef. The conversation also touches on fasting's impact on health and illuminates the intricate relationship between hunting, nutrition, and human evolution. Challenging common dietary misconceptions, he offers fresh insights into our food choices.
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Plant Defenses
- Plants, being rooted, have evolved chemical defenses (phytoalexins) to deter consumption.
- These phytoalexins, often perceived as beneficial, might negatively impact human health.
Hormesis Types
- Environmental hormesis (sauna, ketosis) and molecular hormesis (plant compounds) differ.
- While both trigger an antioxidant response, molecular hormesis has potential side effects.
Sulforaphane's Downside
- Sulforaphane, while activating the NRF2 system, also has negative effects like DNA damage.
- These side effects are often overlooked, and NRF2 activation can be achieved without plant toxins.